Zobrazeno 1 - 10 of 137 pro vyhledávání: '"Wing Ming Keung"'
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Review
Pueraria. The Genus Pueraria Wing Ming Keung
Publikováno v: Economic Botany, 2004 Oct 01. 58(3), 489-490.
Externí odkaz: https://www.jstor.org/stable/4256845
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4
Herbal Remedies for Alcoholism: Promises and Possible Pitfalls
Autor: David Y.W. Lee, Maurizio Massi, Amir H. Rezvani, Wing-Ming Keung, David H. Overstreet
Publikováno v: Alcoholism: Clinical & Experimental Research. 27:177-185
This review summarizes the findings of the effects on alcohol intake in alcohol-preferring rats of extracts or purified compounds from two of the most promising herbs: kudzu (Pueraria lobata) and St. John's Wort (Hypericum perforatum). It is a summar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57b661fbfb862215ba70b95ce3740b55
https://doi.org/10.1097/01.alc.0000051022.26489.cf
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5
Suppression of Heavy Drinking and Alcohol Seeking by a Selective ALDH-2 Inhibitor
Autor: Ivan Diamond, Maria Pia Arolfo, Tao Guoxin, Bert L. Vallee, Louis G. Lange, Justin T. Gass, Wing Ming Keung, Emanuel Rubin, Helen Anni, Brent Blackburn, Clyde W. Hodge, Peidong Fan, David H. Overstreet, Andrew J Lawrence, Lina Yao, Joyce Besheer, Jeff Zablocki, Kwan Leung, M. Foster Olive
Publikováno v: Alcohol Clin Exp Res
Background: Inherited human aldehyde dehydrogenase 2 (ALDH-2) deficiency reduces the risk for alcoholism. Kudzu plants and extracts have been used for 1,000 years in traditional Chinese medicine to treat alcoholism. Kudzu contains daidzin, which inhi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2eb9ee64b86983d2dd76c876c82771
https://doi.org/10.1111/j.1530-0277.2009.01031.x
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6
Mitochondrial nitrite reduction coupled to soluble guanylate cyclase activation: Lack of evidence for a role in the bioactivation of nitroglycerin
Autor: Bernd Mayer, Matteo Beretta, Michael Russwurm, Kurt Schmidt, Wing Ming Keung, Alexander Kollau, Doris Koesling
Publikováno v: Nitric Oxide. 20:53-60
Reduction of nitrite to nitric oxide (NO) by components of the mitochondrial respiratory chain may link nitroglycerin biotransformation by mitochondrial aldehyde dehydrogenase (ALDH2) to activation of soluble guanylate cyclase (sGC). We used purified
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ddfbe30e7da5cd517334a47a7cc97c
https://doi.org/10.1016/j.niox.2008.09.003
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7
Structure of Daidzin, a Naturally Occurring Anti-Alcohol-Addiction Agent, in Complex with Human Mitochondrial Aldehyde Dehydrogenase
Autor: Guang-Yao Gao, Edward D Lowe, Louise N Johnson, Wing Ming Keung
Publikováno v: Journal of Medicinal Chemistry. 51:4482-4487
The ALDH2*2 gene encoding the inactive variant form of mitochondrial aldehyde dehydrogenase (ALDH2) protects nearly all carriers of this gene from alcoholism. Inhibition of ALDH2 has hence become a possible strategy to treat alcoholism. The natural p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049c23ca8ae5b0d70fcc88d7d42ed12c
https://doi.org/10.1021/jm800488j
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8
Bioactivation of Nitroglycerin by Purified Mitochondrial and Cytosolic Aldehyde Dehydrogenases
Autor: Wing Ming Keung, Matteo Beretta, Alexander Kollau, Walter Goessler, Michael Russwurm, Kurt Schmidt, Bernd Mayer, Karl Gruber, Doris Koesling
Publikováno v: The Journal of Biological Chemistry
Metabolism of nitroglycerin (GTN) to 1,2-glycerol dinitrate (GDN) and nitrite by mitochondrial aldehyde dehydrogenase (ALDH2) is essentially involved in GTN bioactivation resulting in cyclic GMP-mediated vascular relaxation. The link between nitrite
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07dbe3ed40cd93b0d6a1ea4f38a96776
https://doi.org/10.1074/jbc.m801182200
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9
Clozapine reduces alcohol drinking in Syrian golden hamsters
Autor: Joseph J. Schildkraut, David T. Chau, Wing Ming Keung, Alan I. Green, Raquelle I. Mesholam, Ree Dawson
Publikováno v: Psychiatry Research. 128:9-20
Alcohol abuse contributes substantially to the overall morbidity of schizophrenia. While typical antipsychotic medications do not limit alcohol use in patients with schizophrenia, emerging data suggest that the atypical antipsychotic clozapine does.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe624e96ceb4c082552d841ffd7754f0
https://doi.org/10.1016/j.psychres.2004.05.005
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10
Eugenol exhibits antidepressant-like activity in mice and induces expression of metallothionein-III in the hippocampus
Autor: Atsushi Ishige, Kenji Watanabe, Yoshifumi Irie, Naoko Anjiki, Nanae Itokazu, Wing Ming Keung
Publikováno v: Brain Research. 1011:243-246
Here we show that eugenol has an antidepressant-like activity comparable to that of imipramine using a forced swim test and a tail suspension test in mice. Furthermore, we show that both eugenol and imipramine induce brain-derived neurotrophic factor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ed6503f2d024d0d55342a28e009ca9
https://doi.org/10.1016/j.brainres.2004.03.040
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