Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Wing K. Fung"'
Publikováno v:
Biometrics.
Mendelian randomization (MR) utilizes genetic variants as instrumental variables (IVs) to estimate the causal effect of an exposure variable on an outcome of interest even in the presence of unmeasured confounders. However, many MR methods including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34eae837e1729db8324c3283b7d1c37
https://pubmed.ncbi.nlm.nih.gov/35942938
https://pubmed.ncbi.nlm.nih.gov/35942938
Publikováno v:
Computational Statistics & Data Analysis. 129:79-92
The case-control and case-only designs are commonly used to detect the gene–environment (G–E) interaction. In principle, the tests based on these two designs require a pre-specified genetic model to achieve an expected power of detecting the G–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0c10dcebb874587c5b58baa7120e668
https://doi.org/10.1016/j.csda.2018.08.014
https://doi.org/10.1016/j.csda.2018.08.014
Publikováno v:
Briefings in Bioinformatics. 22
Mendelian randomization (MR) is a powerful instrumental variable (IV) method for estimating the causal effect of an exposure on an outcome of interest even in the presence of unmeasured confounding by using genetic variants as IVs. However, the corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc02828e1ed1dc6b1cbb9579dbc3353
https://doi.org/10.1093/bib/bbab019
https://doi.org/10.1093/bib/bbab019
Autor:
Peng Wang, Guimin Gao, Siqi Xu, Nianjun Liu, Baolin Wu, Wing K. Fung, Zhijiang Liang, Yi-Xin Wang
Publikováno v:
Biometrics
Constructing a confidence interval for the ratio of bivariate normal means is a classical problem in statistics. Several methods have been proposed in the literature. The Fieller method is known as an exact method, but can produce an unbounded confid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bf413cec27d1fe73884006139e74b9
https://europepmc.org/articles/PMC7914261/
https://europepmc.org/articles/PMC7914261/
Autor:
Wing K. Fung, Pui Yin Lau
Publikováno v:
Legal medicine (Tokyo, Japan). 47
In forensic investigation, retrieving biological information from DNA evidence is a promising field of interest. One of the applications is on the estimation of the age of the donor based on DNA methylation. A large number of studies focused on age p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e62c78f6f6def5c885689d03f168f2
https://pubmed.ncbi.nlm.nih.gov/32659707
https://pubmed.ncbi.nlm.nih.gov/32659707
Publikováno v:
Genetics Research
The X chromosome is known to play an important role in many sex-specific diseases. However, only a few single-nucleotide polymorphisms on the X chromosome have been found to be associated with diseases. Compared to the autosomes, conducting associati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c6f1e81c9e0c4a9328e1b498be70c8
https://doi.org/10.1017/s0016672320000026
https://doi.org/10.1017/s0016672320000026
Publikováno v:
Statistics in Medicine. 37:1389-1401
This article considers sample size determination for jointly testing a cause-specific hazard and the all-cause hazard for competing risks data. The cause-specific hazard and the all-cause hazard jointly characterize important study end points such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65dd2d80a591ff77de9b3eb9e7d03d01
https://doi.org/10.1002/sim.7590
https://doi.org/10.1002/sim.7590
Publikováno v:
Statistics. 52:84-98
In longitudinal studies, missing responses and mismeasured covariates are commonly seen due to the data collection process. Without cautiousness in data analysis, inferences from the standard statistical approaches may lead to wrong conclusions. In o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8f292f1c8f2c310dac0bd2d414795c2
https://doi.org/10.1080/02331888.2017.1361957
https://doi.org/10.1080/02331888.2017.1361957
Autor:
Haibing Zhao, Wing K. Fung
Publikováno v:
TEST. 27:316-337
Time-course microarray experiments harvested samples at several time points. To reveal the dynamic gene expression changes over time, we need to identify the significant genes and detect the patterns of gene expressions, which may bring directional e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39f31f3a7fe9e6af47d302a75658c914
https://doi.org/10.1007/s11749-017-0547-1
https://doi.org/10.1007/s11749-017-0547-1
Publikováno v:
Annals of Human Genetics. 81:147-160
Genomic imprinting is an epigenetic phenomenon in which the expression of an allele copy depends on its parental origin. This mechanism has been found to play an important role in many complex diseases. Statistical tests for imprinting effects have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e05c9711577a80f347e13596e265d0ca
https://doi.org/10.1111/ahg.12195
https://doi.org/10.1111/ahg.12195