Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Wing Hang Ip"'
Autor:
Margarita Valdés Alemán, Luca D. Bertzbach, Thomas Speiseder, Wing Hang Ip, Ramón A. González, Thomas Dobner
Publikováno v:
Viruses, Vol 14, Iss 11, p 2428 (2022)
It is well established that human adenoviruses such as species C, types 2 and 5 (HAdV-C2 and HAdV-C5), induce a nearly complete shutoff of host-cell protein synthesis in the infected cell, simultaneously directing very efficient production of viral p
Externí odkaz:
https://doaj.org/article/ae532ec80eba48a080de84895af529d4
Autor:
Wing-Hang Ip, Marie Fiedler, Britta Gornott, Malte Morische, Luca D. Bertzbach, Thomas Dobner
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Various viral proteins are post-translationally modified by SUMO-conjugation during the human adenovirus (HAdV) replication cycle. This modification leads to diverse consequences for target proteins as it influences their intracellular localization o
Externí odkaz:
https://doaj.org/article/f3b7ef2bed9b4247a8f1514a7f3eb566
Publikováno v:
Tumour Virus Research, Vol 15, Iss , Pp 200254- (2023)
The human adenovirus species C type 5 (HAdV-C5) early region 4 (E4) encodes several distinct polypeptides, defined as E4orf1 to E4orf6/7 according to the order and arrangement of the corresponding open reading frames (ORFs). All E4 gene products oper
Externí odkaz:
https://doaj.org/article/c738b6b116184c248a6a6ba4f52977af
Autor:
Nafiseh Chalabi Hagkarim, Wing-Hang Ip, Luca D. Bertzbach, Tareq Abualfaraj, Thomas Dobner, David P. Molloy, Grant S. Stewart, Roger J. Grand
Publikováno v:
Viruses, Vol 15, Iss 12, p 2356 (2023)
The adenovirus C5 E1B-55K protein is crucial for viral replication and is expressed early during infection. It can interact with E4orf6 to form a complex that functions as a ubiquitin E3 ligase. This complex targets specific cellular proteins and mar
Externí odkaz:
https://doaj.org/article/70c0ec2ab3a84553b93bda7fdf4c4449
Autor:
Marie Fiedler, Wing-Hang Ip, Helga Hofmann-Sieber, Britta Wilkens, Francis K. Nkrumah, Wenli Zhang, Anja Ehrhardt, Luca D. Bertzbach, Thomas Dobner
Publikováno v:
Viruses, Vol 14, Iss 3, p 463 (2022)
The human adenovirus type C5 (HAdV-C5) E1B-55K protein is a multifunctional regulator of HAdV-C5 replication, participating in many processes required for maximal virus production. Its multifunctional properties are primarily regulated by post-transl
Externí odkaz:
https://doaj.org/article/0a49b2740d8945caa0ea7070fff80060
Autor:
von Stromberg, Konstantin, Seddar, Laura, Wing-Hang Ip, Günther, Thomas, Gornott, Britta, Weinert, Sophie-Celine, Hüppner, Max, Bertzbach, Luca D., Dobner, Thomas
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/31/2023, Vol. 120 Issue 44, p1-12, 30p
Autor:
Jana Boddin, Wing-Hang Ip, Britta Wilkens, Konstantin von Stromberg, Wilhelm Ching, Emre Koyuncu, Luca D. Bertzbach, Thomas Dobner
Publikováno v:
mBio. 13
Adenoviruses are very efficient high-capacity vaccine vectors and are common gene delivery systems. Despite their extensive use in preclinical models and clinical trials over the past decades, adenoviral vectors still require optimization. To achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596f115e0a1b714274e97febbc210121
https://doi.org/10.1128/mbio.00144-22
https://doi.org/10.1128/mbio.00144-22
Publikováno v:
FEBS Letters. 593:3504-3517
The adenovirus E1B 55K (E1B) protein plays major roles in productive adenoviral infection and cellular transformation. Interest in E1B increased because of the potential of adenoviruses as therapeutic vectors, and the E1B gene is commonly deleted fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffb2c583d763e5aba8af985572e91b8
https://doi.org/10.1002/1873-3468.13694
https://doi.org/10.1002/1873-3468.13694
Publikováno v:
Biology
Biology, Vol 10, Iss 1253, p 1253 (2021)
Biology, Vol 10, Iss 1253, p 1253 (2021)
Simple Summary Animal models are widely used to study various aspects of human diseases and disorders. Likewise, they are indispensable for preclinical testing of medicals and vaccines. Human adenovirus infections are usually self-limiting, and can c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080f7fb5049981dfd13341c309517227
http://europepmc.org/articles/PMC8698265
http://europepmc.org/articles/PMC8698265
Autor:
Wencong Cui, Marios Xydous, Alexander Haschke, Katharina Korf, Michael Spohn, Daniel Pohlmann, Steve Sweet, Wing Hang Ip, Antonina Wrzeszcz, Daniela Indenbirken, Hui Ma, Jürgen Müller, Anne Kruchen, Thomas Sternsdorf
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a49c235b795a65378c3b1220a4e0065b
https://doi.org/10.2139/ssrn.3961044
https://doi.org/10.2139/ssrn.3961044