Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Wing‐Hon Lai"'
Autor:
Si-Jia Sun, Fei Li, Ming Dong, Wei-Hao Liang, Wing-Hon Lai, Wai-In Ho, Rui Wei, Yan Huang, Song-Yan Liao, Hung-Fat Tse
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
A combination of repeated systemic infusion and local transplantation of hiPSC-MSCs could enhance regenerative therapies for cardiovascular disease.
Externí odkaz:
https://doaj.org/article/70a8f68d141848cbbf08d23051147158
Autor:
Ka-Chun Un, Chun-Ka Wong, Yuk-Ming Lau, Jeffrey Chun-Yin Lee, Frankie Chor-Cheung Tam, Wing-Hon Lai, Yee-Man Lau, Hao Chen, Sandi Wibowo, Xiaozhu Zhang, Minghao Yan, Esther Wu, Soon-Chee Chan, Sze-Ming Lee, Augustine Chow, Raymond Cheuk-Fung Tong, Maulik D. Majmudar, Kuldeep Singh Rajput, Ivan Fan-Ngai Hung, Chung-Wah Siu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Patients infected with SARS-CoV-2 may deteriorate rapidly and therefore continuous monitoring is necessary. We conducted an observational study involving patients with mild COVID-19 to explore the potentials of wearable biosensors and machin
Externí odkaz:
https://doaj.org/article/35f4fd065cc24417bdbfa6fb5c1c8392
Autor:
Rui Wei, Jiayin Yang, Chi-Wa Cheng, Wai-In Ho, Na Li, Yang Hu, Xueyu Hong, Jian Fu, Bo Yang, Yuqing Liu, Lixiang Jiang, Wing-Hon Lai, Ka-Wing Au, Wai-Ling Tsang, Yiu-Lam Tse, Kwong-Man Ng, Miguel A. Esteban, Hung-Fat Tse
Publikováno v:
JHEP Reports, Vol 4, Iss 1, Pp 100389- (2022)
Background & Aims: Wilson’s disease (WD) is an autosomal recessive disorder of copper metabolism caused by loss-of-function mutations in ATP7B, which encodes a copper-transporting protein. It is characterized by excessive copper deposition in tissu
Externí odkaz:
https://doaj.org/article/7251fd1424cb470896b40e7153068479
Autor:
Songyan Liao, Yuelin Zhang, Sherwin Ting, Zhe Zhen, Fan Luo, Ziyi Zhu, Yu Jiang, Sijia Sun, Wing-Hon Lai, Qizhou Lian, Hung-Fat Tse
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2019)
Abstract Background Optimal cell type as cell-based therapies for heart failure (HF) remains unclear. We sought to compare the safety and efficacy of direct intramyocardial transplantation of human embryonic stem cell-derived cardiomyocytes (hESC-CMs
Externí odkaz:
https://doaj.org/article/dadbd1f8337844ed8e3a64e22e3c10d7
Autor:
Min Zhou, Rui Wei, Yu Jiang, Jian Fu, Yuqing Liu, Bo Yang, Baorong Yu, Yun Lin, Xinru Ran, Wing-Hon Lai, Meng Chu, Yang Hu, Jiayin Yang, Hung-Fat Tse
Publikováno v:
Stem Cell Research, Vol 50, Iss , Pp 102120- (2021)
The human transcription factor NKX2-5 plays an important role in cardiac formation and development, and thus it can be used for isolation of cardiomyocytes (CMs) differentiated from human pluripotent stem cells (hPSCs). Here, we knocked-in enhanced G
Externí odkaz:
https://doaj.org/article/a3138ff90dcd4ce3a70c893b607fe0e8
Autor:
Mi Zhou, Chun-Ka Wong, Ka-Chun Un, Yuk-Ming Lau, Jeffrey Chun-Yin Lee, Frankie Chor-Cheung Tam, Yee-Man Lau, Wing-Hon Lai, Anthony Raymond Tam, Yat-Yin Lam, Polly Pang, Teresa Tong, Milky Tang, Hung-Fat Tse, Deborah Ho, Ming-Yen Ng, Esther W Chan, Ian C K Wong, Chu-Pak Lau, Ivan Fan-Ngai Hung, Chung-Wah Siu
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246732 (2021)
BackgroundA high proportion of COVID-19 patients were reported to have cardiac involvements. Data pertaining to cardiac sequalae is of urgent importance to define subsequent cardiac surveillance.MethodsWe performed a systematic cardiac screening for
Externí odkaz:
https://doaj.org/article/2b78e2dd58d142a58cf44c9353d03c16
Autor:
Kwong-Man Ng, Yee-Man Lau, Vidhu Dhandhania, Zhu-Jun Cai, Yee-Ki Lee, Wing-Hon Lai, Hung-Fat Tse, Chung-Wah Siu
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Empagliflozin, a sodium-glucose co-transporter (SGLT) inhibitor, reduces heart failure and sudden cardiac death but the underlying mechanisms remain elusive. In cardiomyocytes, SGLT1 and SGLT2 expression is upregulated in diabetes mellitus,
Externí odkaz:
https://doaj.org/article/645fea2d98e649728a8b8a8d073e5a30
Autor:
Song-Yan Liao, MD, Zhe Zhen, MD, Yuan Liu, MD, PhD, Kai-Wing Au, PhD, Wing-Hon Lai, PhD, Anita Tsang, BSc, Hung-Fat Tse, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 3, Pp 270-281 (2017)
Summary: Renal denervation (RD) is a potential novel nonpharmacological therapy for heart failure (HF). We performed bilateral catheter-based RD in 10 adult pigs and compared them with 10 control subjects after induction of HF to investigate the long
Externí odkaz:
https://doaj.org/article/31c1963549a5499c8e5cc079a174cab6
Autor:
Jiayin Yang, Yu Wang, Ting Zhou, Lai-Yung Wong, Xiao-Yu Tian, Xueyu Hong, Wing-Hon Lai, Ka-Wing Au, Rui Wei, Yuqing Liu, Lai-Hung Cheng, Guichan Liang, Zhijian Huang, Wenxia Fan, Ping Zhao, Xiwei Wang, David P. Ibañez, Zhiwei Luo, Yingying Li, Xiaofen Zhong, Shuhan Chen, Dongye Wang, Li Li, Liangxue Lai, Baoming Qin, Xichen Bao, Andrew P. Hutchins, Chung-Wah Siu, Yu Huang, Miguel A. Esteban, Hung-Fat Tse
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 605-618 (2017)
Familial hypercholesterolemia (FH) causes elevation of low-density lipoprotein cholesterol (LDL-C) in blood and carries an increased risk of early-onset cardiovascular disease. A caveat for exploration of new therapies for FH is the lack of adequate
Externí odkaz:
https://doaj.org/article/c8b746bcc4d14c1ea35c0ee1de8c99b8
Autor:
Cheuk-Yiu Law, Chung-Wah Siu, Katherine Fan, Wing-Hon Lai, Ka-Wing Au, Yee-Man Lau, Lai-Yung Wong, Jenny C.Y. Ho, Yee-ki Lee, Hung-Fat Tse, Kwong-Man Ng
Publikováno v:
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 335-345 (2016)
Patients with Danon disease may suffer from severe cardiomyopathy, skeletal muscle dysfunction as well as varying degrees of mental retardation, in which the primary deficiency of lysosomal membrane-associated protein-2 (LAMP2) is considerably associ
Externí odkaz:
https://doaj.org/article/4cbe27ca77554746ac132bf11ac8ccbb