Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Winfried Kammer"'
Autor:
Thomas Rückrich, Winfried Kammer, D Burg, Michael Reich, Jeannette Gogel, Huib Ovaa, Celia R. Berkers, Alexander Beck, Herman S. Overkleeft, Marianne Kraus, Christoph Driessen
Publikováno v:
Leukemia. 21:84-92
Proteasomal proteolysis relies on the activity of six catalytically active proteasomal subunits (beta1, beta2, beta5, beta1i, beta2i and beta5i). Applying a functional proteomics approach, we used a recently developed activity-based, cell-permeable p
Autor:
Winfried Kammer, M. Pascu, Michael Gregor, Martin Priemer, Reinhild Klein, Sebastian Wesselborg, Peter A. Berg, Thomas Berg, Gerburg M. Stein, Alfred Nordheim, Klaus Schulze-Osthoff, Christoph P. Berg
Publikováno v:
Liver International. 26:846-855
Background: Primary biliary cirrhosis (PBC) is characterized by the presence of antimitochondrial antibodies (AMA). Autoantibodies specific for the mitochondrial M4 antigen can be detected by a complement fixation test (CFT) but not by immunoblotting
Autor:
Volkmar Braun, Gerold Schwarz, Heidi Neugebauer, Alfred Nordheim, Christina Herrmann, Winfried Kammer
Publikováno v:
Journal of Bacteriology. 187:8300-8311
Analysis of the genome sequence of Caulobacter crescentus predicts 67 TonB-dependent outer membrane proteins. To demonstrate that among them are proteins that transport nutrients other than chelated Fe 3+ and vitamin B 12 —the substrates hitherto k
Autor:
Gerold Schwarz, Reinhard Walther, Lary C. Walker, Aurel Popa-Wagner, Winfried Kammer, Yalikun Suofu, Alfred Nordheim, Christof Kessler, Heike Junker, Kira Späte, Uwe Runge
Publikováno v:
Epilepsia. 46:339-343
Summary: Purpose: Kindled seizures are widely used to model epileptogenesis, but the molecular mechanisms underlying the attainment of kindling status are largely unknown. Recently we showed that achievement of kindling status in the Sprague‐ Dawle
Autor:
Timo Burster, Hubert Kalbacher, Michael Reich, Winfried Kammer, Alfred Nordheim, Marianne Kraus, Christoph Driessen, Jens Brandenburg, Ekkehard Weber, Herman S. Overkleeft, Alfred Lautwein, Gerold Schwarz
Publikováno v:
Journal of Leukocyte Biology. 75:844-855
Endocytic proteolysis represents a major functional component of the major histocompatibility complex class II antigen-presentation machinery. Although transport and assembly of class II molecules in the endocytic compartment are well characterized,
Autor:
Martin Priemer, Martin Vingron, Alfred Nordheim, Winfried Kammer, Michael A. Cahill, Giang Lam Vuong, Stefanie M. Weiss
Publikováno v:
Electrophoresis. 21:2594-2605
We describe approaches to improve the detection of proteins by postharvest alkylation and subsequent radioactive labeling with either [3H]iodoacetamide or 125I. Database protein sequence analysis suggested that cysteine is not suitable for detection
Autor:
Winfried Kammer, Stephanie Brändlein, Ingrid Erhardt, Karlheinz Friedrich, Stefan Arnold, Walter Sebald
Publikováno v:
European Journal of Biochemistry. 265:457-465
Interleukin-4 (IL-4) triggers cellular responses by interaction with the bipartite interleukin-4 receptor (IL-4R). IL-4-responsive cells specifically endocytose IL-4. We studied the ligand internalization properties of the human IL-4R and analyzed th
Autor:
Ingrid Erhardt, Antje Lischke, Karlheinz Friedrich, B. Schnarr, Bernd Groner, Susanne Berchtold, Richard Moriggl, Winfried Kammer
Publikováno v:
European Journal of Biochemistry. 251:25-35
Stimulation of susceptible cells by interleukin-4 leads to activation of signal transducer and activator of transcription (STAT6) through tyrosine phosphorylation and dimerisation, thus directing it to the cell nucleus and rendering it a sequence-spe
Publikováno v:
Analytical Biochemistry. 236:322-326
Enhanced chemiluminescence was applied to detect the binding of monoclonal antibodies to surface antigens on intact cells. The fast and simple assay is performed in the microtiter scale and thus allows for the simultaneous processing of a large numbe
Publikováno v:
European Journal of Biochemistry. 234:100-107
Interleukin-4 (IL-4) shows species-specific activity due to species-restricted interaction with the IL-4 receptor alpha (IL-4R alpha) chain. The second subunit of a functional IL-4 receptor, the common gamma chain (gamma c), is more promiscuous, sinc