Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Winfried Hofmann"'
Autor:
Ming Tang, Željko Antić, Pedram Fardzadeh, Stefan Pietzsch, Charlotte Schröder, Adrian Eberhardt, Alena van Bömmel, Gabriele Escherich, Winfried Hofmann, Martin A. Horstmann, Thomas Illig, J. Matt McCrary, Jana Lentes, Markus Metzler, Wolfgang Nejdl, Brigitte Schlegelberger, Martin Schrappe, Martin Zimmermann, Karolina Miarka-Walczyk, Agata Patsorczak, Gunnar Cario, Bernhard Y. Renard, Martin Stanulla, Anke Katharina Bergmann
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105171- (2024)
Summary: Background: The increasing volume and intricacy of sequencing data, along with other clinical and diagnostic data, like drug responses and measurable residual disease, creates challenges for efficient clinical comprehension and interpretatio
Externí odkaz:
https://doaj.org/article/73ab5d4f744341ce91b017ca5e0c00a9
Autor:
Natali Froese, Malgorzata Szaroszyk, Paolo Galuppo, Joseph R. Visker, Christopher Werlein, Mortimer Korf‐Klingebiel, Dominik Berliner, Marc R. Reboll, Rana Hamouche, Simona Gegel, Yong Wang, Winfried Hofmann, Ming Tang, Robert Geffers, Adam R. Wende, Mark P. Kühnel, Danny D. Jonigk, Georg Hansmann, Kai C. Wollert, E. Dale Abel, Stavros G. Drakos, Johann Bauersachs, Christian Riehle
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)
Background Alveolar hypoxia is protective in the context of cardiovascular and ischemic heart disease; however, the underlying mechanisms are incompletely understood. The present study sought to test the hypothesis that hypoxia is cardioprotective in
Externí odkaz:
https://doaj.org/article/faab23b5566643d4bb708c9cafa2f8de
Autor:
Jonathan L. Lühmann, Martin Zimmermann, Winfried Hofmann, Anke K. Bergmann, Anja Möricke, Gunnar Cario, Martin Schrappe, Brigitte Schlegelberger, Martin Stanulla, Doris Steinemann
Publikováno v:
Haematologica, Vol 109, Iss 5 (2023)
Externí odkaz:
https://doaj.org/article/7181ed27e0e34a71955daa8b4851e16e
Autor:
Jonathan Lühmann, Winfried Hofmann, Anke Katharina Bergmann, Anja Möricke, Gunnar Cario, Martin Schrappe, Brigitte Schlegelberger, Martin Zimmermann, Martin Stanulla, Doris Steinemann
Publikováno v:
HemaSphere, Vol 7, p e3002627 (2023)
Externí odkaz:
https://doaj.org/article/f78e65b1beb74f32b2a19b0517e8b389
Autor:
Yvonne Poker, Sandra von Hardenberg, Winfried Hofmann, Ming Tang, Ulrich Baumann, Nicolaus Schwerk, Martin Wetzke, Viola Lindenthal, Bernd Auber, Brigitte Schlegelberger, Hagen Ott, Philipp von Bismarck, Dorothee Viemann, Frank Dressler, Christian Klemann, Anke Katharina Bergmann
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Monogenic autoinflammatory diseases (AID) encompass a growing group of inborn errors of the innate immune system causing unprovoked or exaggerated systemic inflammation. Diagnosis of monogenic AID requires an accurate description of the patients’ p
Externí odkaz:
https://doaj.org/article/798bbf38737a4fb8bca2390d2862a34a
Autor:
Alexander Varzari, Igor V. Deyneko, Gitte Hoffmann Bruun, Maja Dembic, Winfried Hofmann, Victor M. Cebotari, Sergei S. Ginda, Brage S. Andresen, Thomas Illig
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Inborn errors of immunity are known to influence susceptibility to mycobacterial infections. The aim of this study was to characterize the genetic profile of nine patients with mycobacterial infections (eight with BCGitis and one with disseminated tu
Externí odkaz:
https://doaj.org/article/45a80c359357407798df86e0a462fdeb
Autor:
Jana Lisa vanLuttikhuizen, Janin Bublitz, Stephanie Schubert, Gunnar Schmidt, Winfried Hofmann, Susanne Morlot, Reena Buurman, Bernd Auber, Brigitte Schlegelberger, Doris Steinemann
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 9, Pp n/a-n/a (2020)
Abstract Background Germline mutations in BRCA1/2 significantly contribute to hereditary breast and/or ovarian cancer. Here, we report a novel BRCA2 duplication of exons 22–24 in a female patient with bilateral breast cancer at age 35 and 44. The d
Externí odkaz:
https://doaj.org/article/5ee4a474c73542fc8b32f388bb2f04f9
Autor:
Judith Penkert, Gunnar Schmidt, Winfried Hofmann, Stephanie Schubert, Maximilian Schieck, Bernd Auber, Tim Ripperger, Karl Hackmann, Marc Sturm, Holger Prokisch, Ursula Hille-Betz, Dorothea Mark, Thomas Illig, Brigitte Schlegelberger, Doris Steinemann
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-16 (2018)
Abstract Background Breast cancer is the most prevalent tumor entity in Li-Fraumeni syndrome. Up to 80% of individuals with a Li-Fraumeni-like phenotype do not harbor detectable causative germline TP53 variants. Yet, no systematic panel analyses for
Externí odkaz:
https://doaj.org/article/e22f263cf37d4328b380d9088edc9000
Autor:
Tim Ripperger, Winfried Hofmann, Jan C. Koch, Katayoon Shirneshan, Detlef Haase, Gerald Wulf, Peter R. Issing, Matthias Karnebogen, Gunnar Schmidt, Bernd Auber, Brigitte Schlegelberger, Thomas Illig, Birgit Zirn, Doris Steinemann
Publikováno v:
Haematologica, Vol 103, Iss 2 (2018)
Externí odkaz:
https://doaj.org/article/af110bbbb64a47e1928006932ade6439
Autor:
Simone Feurstein, Kathrin Thomay, Winfried Hofmann, Guntram Buesche, Hans Kreipe, Felicitas Thol, Michael Heuser, Arnold Ganser, Brigitte Schlegelberger, Gudrun Göhring
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3269 (2018)
Myelodysplastic syndrome (MDS) can easily transform into acute myeloid leukemia (AML), a process which is often associated with clonal evolution and development of complex karyotypes. Deletion of 5q (del(5q)) is the most frequent aberration in comple
Externí odkaz:
https://doaj.org/article/a23e7edceb684caeb9276709bc4b64c8