Germline TET2 loss of function causes childhood immunodeficiency and lymphoma.

Autor: Stremenova Spegarova J; Primary Immunodeficiency Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom., Lawless D; Leeds Institute of Medical Research, St. James's University Hospital, University of Leeds, Leeds, United Kingdom., Mohamad SMB; Regenerative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, Penang, Malaysia., Engelhardt KR; Primary Immunodeficiency Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom., Doody G; Leeds Institute of Medical Research, St. James's University Hospital, University of Leeds, Leeds, United Kingdom., Shrimpton J; Leeds Institute of Medical Research, St. James's University Hospital, University of Leeds, Leeds, United Kingdom., Rensing-Ehl A; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Freiburg, Germany., Ehl S; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Freiburg, Germany., Rieux-Laucat F; Université de Paris, Institut Imagine, Paris, France., Cargo C; Haematological Malignancy Diagnostic Service, St James's University Hospital, Leeds, United Kingdom., Griffin H; Primary Immunodeficiency Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom., Mikulasova A; Newcastle University Biosciences Institute, Newcastle upon Tyne, United Kingdom., Acres M; Primary Immunodeficiency Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom., Morgan NV; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Poulter JA; Leeds Institute of Medical Research, St. James's University Hospital, University of Leeds, Leeds, United Kingdom., Sheridan EG; Leeds Institute of Medical Research, St. James's University Hospital, University of Leeds, Leeds, United Kingdom., Chetcuti P; Department of Paediatrics, Leeds General Infirmary, Leeds, United Kingdom., O'Riordan S; Department of Paediatrics, Leeds General Infirmary, Leeds, United Kingdom., Anwar R; Leeds Institute of Medical Research, St. James's University Hospital, University of Leeds, Leeds, United Kingdom., Carter CR; Department of Clinical Immunology and Allergy, St James's University Hospital, Leeds, United Kingdom., Przyborski S; Department of Biosciences, Durham University, Durham, United Kingdom., Windebank K; Wolfson Childhood Cancer Research Centre, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom., Cant AJ; Primary Immunodeficiency Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom.; Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., Lako M; Newcastle University Biosciences Institute, Newcastle upon Tyne, United Kingdom., Bacon CM; Wolfson Childhood Cancer Research Centre, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom.; Department of Cellular Pathology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; and., Savic S; Department of Clinical Immunology and Allergy, St James's University Hospital, Leeds, United Kingdom.; NIHR, Leeds Biomedical Research Centre and Leeds Institute of Rheumatic and Musculoskeletal Medicine, Wellcome Trust Brenner Building, St James's University Hospital, Leeds, United Kingdom., Hambleton S; Primary Immunodeficiency Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom.; Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.

Publikováno v: Blood [Blood] 2020 Aug 27; Vol. 136 (9), pp. 1055-1066.

The United Kingdom Childhood Cancer Study: objectives, materials and methods. UK Childhood Cancer Study Investigators

Autor: Boulton, A, Boyd, P, Cheng, KK, Cook, J, Gilman, EA, Lunt, D, Mahler, H, Walker, C, Wardroper, M, Darbyshire, PJ, Hill, FGH, Mann, JR, Morland, B, Raafat, F, Stevens, MCG, Ahmed, A, Amos, P, Bone, V, Bonney, S, Bray, M, Cambouropoulos, P, Cook, S, Day, N, Elkins, S, Hensel, F, Lucas, P, Pettinger, J, Pugsley, M, Ruja, E, Skinner, J, Williams, D, Braodbent, V, Williams, M, Alcock, M, Bell, K, Buchan, M, Cartwright, R, Cusack, H, Fear, N, Griffiths, S, Jarvis, J, Johnson, P, Kane, E, Law, G, Moorman, A, Prajapati, J, Roberts, P, Roman, E, Simpson, J, Sinclair, V, Staines, A, Thackrah, C, Thistlethwaite, S, Waller, B, Bailey, C, Kinsey, S, Lewis, I, Picton, S, Squire, R, Taylor, R, Beck, JM, Doran, RML, Livingston, JH, Van Hille, P, Beddis, I, Cameron, MM, Craft, A, Hale, J, Kernahan, J, Reid, M, Windebank, K, Pearson, A, Skinner, R, Marks, S, Achilles, J, Alam, S, Birch, JM, Blair, V, Buckley, B, Clarkson, M, Eden, OB, Howell, S, Kellaway, C, Lashford, L, Leeke, S, Leggett, P, Murphy, AV, O'Rorke, C, Panton, S, Paxon, J, Pots, H, Roberts, C, Rothwell, J, Stephenson, W, Whelpton, B, Caswell, M, McDowell, H, Pizer, BL, Gattamaneri, R, Brock, J, Kelsey, AM, Stevens, R, Will, A, Brennan, B, Brydon, J, Dodds, C, Findlay, E, Finucane, J, Fraser, J, Harkness, E, Heary, A, Hunter, N, Juszczak, E, Lang, M, Lapsley, E, McArthur, A, MacCalman, A, McKinney, PA, Proudfoot, K, Smith, C, Smith, K, Stockton, D, Thomson, CS, Vickers, R, Wilkie, R, King, D, Mackinlay, G, Shaw, P, Thomas, A, Wallace, H, Carachi, R, Gibson, BS, Simpson, E, Cruickshank, G, Hide, TAH, Gregor, A, Steers, AJW, Barrett, A, Hamblen, DL, Kaye, SB, Mackie, R, Allen, A, Jones, AA, Beeby, S, Bignall, V, Breeze, L, Deacon, J, MacDonald, M, Matthews, F, Meggitt, C, Peto, J, Sharpe, E, Spencer, C, Swales, J, Thorne, M, Trowbridge, P, Webster-King, J, Williams, E, Bell, BA, Johnston, FG, Marsh, HT, Uttley, D, Bartlett, J, Evans, A, Gullan, RW, Glaser, MG, Peterson, D, Southcott, BM, Cavanagh, N, Pearl, K, Scott, D, Darby, CW, Chessels, J, Evans, J, Gaze, M, Hann, IM, Harkness, W, Hayward, R, Michalski, A, Passmore, J, Phillips, M, Pritchard, J, Clark, KGA, MacDonald, EA, Neville, BGR, Robb, SA, Robinson, RO, Hardwidge, C, Padgham, N, Lobo, VJ, Keen, C, Hindmarsh, PC, Kilby, AM, Souhami, RL, Tuft, S, Thomas, RM, Ward, P, Scott, M, Hoffbrand, AV, Prentice, HG, Gutteridge, CG, Newland, AC, Brada, M, Henk, JM, Meller, S, Pinkerton, R, Jones, KP, Cannon, S, Murrell, DS, Hungerford, JL, Kingston, JE, Plowman, PN, Young, B, Ball, SE, Capps, SNJ, Davies, EG, Holmes, SJK, Carr, R, Mercer, DM, Smith, MA, Andrews, VE, Hughes, RG, Ansell, P, Baker, K, Beral, V, Black, J, Boon, S, Burge, C, Burge, F, Cliff, A, Deciaccio, D, Dorman, P, Heydon, F, Langley, N, Pelerin, M, Roemmele, J, Sayers, K, Townshend, P, Harman, S, Loftus, J, Roth, S, Lee, B, Buchdahl, R, Dunger, DB, Mitchell, C, Moncrieff, MKM, Tam, PKH, Wheeler, K, Reiser, J, Joss, V, Moir, DJ, Darmady, J, Daish, P, Liberman, MM, Al-Izzi, MS, Adams, CBT, Kerr, RSC, Teddy, PJ, Barton, CJ, Newman, CL, Gabriel, CM, O'Hea, M, Sherrin, S, Watson, A, Douek, E, Connell, JA, Kelly, S, Beswick, A, Eldridge, B, Elwood, P, Hughes, J, Webb, D, Alexander, FE, Bennett-Lloyd, B, Davis, A, Dunn, R, Little, J, Longdon, S, Mitchell, M, Muir, S, Sturitis, J, Kennedy, C, Kohler, J, Lang, D, Radford, M, Foreman, N, Foot, A, Mott, M, Noblett, H, Oakhill, A, Sandeman, D, Baumer, J, McNinch, A, Gilbertson, N, Bosley, A, Richardson, S, Challacombe, D, French, T, Bate, L, Chilvers, CED, Faulkner, G, Hawtin, P, Jenkinson, C, Kelham, P, Mackie, I, Mackie, M, Muir, KR, O'Dwyer, J, Williams, A, Nelson, C, Howarth, C, Madi, M, Shannon, R, Forman, K, Hewitt, M, Punt, J, Walker, D, Gerrard, M, Lilleyman, JS, Vora, A, Draper, G, Harrison, C, Doll, R, Richards, S, Ayres, M, Carter, R, Dearden, SP, Hussain, A, Kennedy, J, Ravetto, P, Ruprai, A, Taylor, GM, Taylor, J, Watson, PD, Colman, SM, Greaves, MF, Price, CM, Goodhead, DT, Allen, S, Bartlett, D, Blackwell, RP, Fry, F, Maslanyj, M, Mee, T, Miles, J, Adams, G, Investigat, UKCCS

Publikováno v: British journal of cancer. 82(5)

An investigation into the possible causes of childhood cancer has been carried out throughout England, Scotland and Wales over the period 1991-1998. All children known to be suffering from one or other type of the disease over periods of 4-5 years ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::db0ec36ea837ea67c7c9c4efd0a8edc2
http://ora.ox.ac.uk/objects/uuid:53d2fa2f-a325-4c28-b597-672368107ed3

Childhood lymphoma.

Autor: Windebank, Kevin, Windebank, K

Publikováno v: Indian Journal of Pediatrics; Sep1998, Vol. 65 Issue 5, p669-680, 12p

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