Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Wim van Duyvenvoorde"'
Autor:
Eveline Gart, Wim van Duyvenvoorde, Jessica M. Snabel, Christa de Ruiter, Joline Attema, Martien P.M. Caspers, Serene Lek, Bertie Joan van Heuven, Arjen G.C.L. Speksnijder, Martin Giera, Aswin Menke, Kanita Salic, Kendra K. Bence, Gregory J. Tesz, Jaap Keijer, Robert Kleemann, Martine C. Morrison
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e13985- (2023)
Background: NAFLD progression, from steatosis to inflammation and fibrosis, results from an interplay of intra- and extrahepatic mechanisms. Disease drivers likely include signals from white adipose tissue (WAT) and gut. However, the temporal dynamic
Externí odkaz:
https://doaj.org/article/80936c4a408e43e2adff608faadaaab7
Autor:
Florine Seidel, Robert Kleemann, Wim van Duyvenvoorde, Nikki van Trigt, Nanda Keijzer, Sandra van der Kooij, Cees van Kooten, Lars Verschuren, Aswin Menke, Amanda J. Kiliaan, Johnathan Winter, Timothy R. Hughes, B. Paul Morgan, Frank Baas, Kees Fluiter, Martine C. Morrison
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10736 (2022)
Background: Chronic inflammation is an important driver in the progression of non-alcoholic steatohepatitis (NASH) and atherosclerosis. The complement system, one of the first lines of defense in innate immunity, has been implicated in both diseases.
Externí odkaz:
https://doaj.org/article/8ac9af891c33464eae515a193ee5e899
Autor:
Andrea M. Mueller, Robert Kleemann, Eveline Gart, Wim van Duyvenvoorde, Lars Verschuren, Martien Caspers, Aswin Menke, Natascha Krömmelbein, Kanita Salic, Yvonne Burmeister, Bernd Seilheimer, Martine C. Morrison
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundNon-alcoholic fatty liver disease (NAFLD) is a complex multifactorial disorder that is characterised by dysfunctional lipid metabolism and cholesterol homeostasis, and a related chronic inflammatory response. NAFLD has become the most commo
Externí odkaz:
https://doaj.org/article/fd0f49bca8f34e1ba51bb91bc30b7b07
Autor:
Martine C. Morrison, Eveline Gart, Wim van Duyvenvoorde, Jessica Snabel, Mette Juul Nielsen, Diana Julie Leeming, Aswin Menke, Robert Kleemann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2325 (2022)
The development of non-alcoholic steatohepatitis (NASH) has been associated with alterations in gut microbiota composition and reduced gut barrier function. Akkermansia muciniphila is a gut microbe that is thought to have health-promoting properties,
Externí odkaz:
https://doaj.org/article/e681d4a8f3684ee8a2369c50fe6284b3
Autor:
Eveline Gart, Wim van Duyvenvoorde, Karin Toet, Martien P. M. Caspers, Lars Verschuren, Mette Juul Nielsen, Diana Julie Leeming, Everton Souto Lima, Aswin Menke, Roeland Hanemaaijer, Jaap Keijer, Kanita Salic, Robert Kleemann, Martine C. Morrison
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1954 (2021)
In obesity-associated non-alcoholic steatohepatitis (NASH), persistent hepatocellular damage and inflammation are key drivers of fibrosis, which is the main determinant of NASH-associated mortality. The short-chain fatty acid butyrate can exert metab
Externí odkaz:
https://doaj.org/article/d68615dbae2a4f9ab2273c659445ae93
Autor:
Eveline Gart, Kanita Salic, Martine C. Morrison, Martien Caspers, Wim van Duyvenvoorde, Marieke Heijnk, Martin Giera, Ivana Bobeldijk-Pastorova, Jaap Keijer, Andreas B. Storsve, Petter-Arnt Hals, Robert Kleemann
Publikováno v:
Nutrients, Vol 13, Iss 8, p 2836 (2021)
The development of obesity is characterized by the metabolic overload of tissues and subsequent organ inflammation. The health effects of krill oil (KrO) on obesity-associated inflammation remain largely elusive, because long-term treatments with KrO
Externí odkaz:
https://doaj.org/article/6a32859722444d61b2f24d8a4391b46e
Autor:
Kanita Salic, Eveline Gart, Florine Seidel, Lars Verschuren, Martien Caspers, Wim van Duyvenvoorde, Kari E. Wong, Jaap Keijer, Ivana Bobeldijk-Pastorova, Peter Y. Wielinga, Robert Kleemann
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4359 (2019)
Obesity characterized by adiposity and ectopic fat accumulation is associated with the development of non-alcoholic fatty liver disease (NAFLD). Treatments that stimulate lipid utilization may prevent the development of obesity and comorbidities. Thi
Externí odkaz:
https://doaj.org/article/75aae11a33d54f7dbdc55f833729a250
Autor:
Martine C Morrison, Petra Mulder, P Mark Stavro, Manuel Suárez, Anna Arola-Arnal, Wim van Duyvenvoorde, Teake Kooistra, Peter Y Wielinga, Robert Kleemann
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139196 (2015)
As dietary saturated fatty acids are associated with metabolic and cardiovascular disease, a potentially interesting strategy to reduce disease risk is modification of the quality of fat consumed. Vegetable oils represent an attractive target for int
Externí odkaz:
https://doaj.org/article/a8dec6046f004cf7be539d1097e47799
Autor:
Marijana Radonjic, Peter Y Wielinga, Suzan Wopereis, Thomas Kelder, Varshna S Goelela, Lars Verschuren, Karin Toet, Wim van Duyvenvoorde, Bianca van der Werff van der Vat, Johanna H M Stroeve, Nicole Cnubben, Teake Kooistra, Ben van Ommen, Robert Kleemann
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56122 (2013)
Excess caloric intake leads to metabolic overload and is associated with development of type 2 diabetes (T2DM). Current disease management concentrates on risk factors of the disease such as blood glucose, however with limited success. We hypothesize
Externí odkaz:
https://doaj.org/article/23563b5163e340fc81fe9f635717eba9
Autor:
Martine C, Morrison, Eveline, Gart, Wim van, Duyvenvoorde, Jessica, Snabel, Mette Juul, Nielsen, Diana Julie, Leeming, Aswin, Menke, Robert, Kleemann
Publikováno v:
International journal of molecular sciences. 23(4)
The development of non-alcoholic steatohepatitis (NASH) has been associated with alterations in gut microbiota composition and reduced gut barrier function.