Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Wim Van Molle"'
Autor:
Marcel H.N. Hoefnagel, Paul Stickings, Dean Smith, Carmen Jungbäck, Wim Van Molle, Lorenzo Tesolin
Publikováno v:
Expert Review of Vaccines, Vol 22, Iss 1, Pp 369-377 (2023)
Introduction There are rational arguments to replace existing in vivo potency and safety assays for batch release testing of vaccines with more advanced non-animal techniques to measure critical quality attributes. However, the introduction of in vit
Externí odkaz:
https://doaj.org/article/4509f536acc5435da3513fc7a0fa1c3f
Autor:
Joris Vandeputte, Wim Van Molle, Marlies Halder, Jean-Francois Dierick, Julie Lorenz, Carmen Jungbaeck, Patrice Riou, Jean-Marie Préaud, Sylvie Uhlrich, Lorenzo Tesolin
Publikováno v:
Open Research Europe, Vol 2 (2022)
The aim of this letter is to share the discussions and proposals made by the VAC2VAC consortium on how to support the deployment of the “Consistency Approach” for quality control of established vaccines and thus facilitate the substitution of in
Externí odkaz:
https://doaj.org/article/eb11d678489c43e68403b518d0c1d37f
Autor:
Jean-Francois Dierick, Marlies Halder, Carmen Jungbaeck, Julie Lorenz, Jean-Marie Préaud, Patrice Riou, Lorenzo Tesolin, Sylvie Uhlrich, Wim Van Molle, Joris Vandeputte
Publikováno v:
Open Research Europe
The aim of this letter is to share the discussions and proposals made by the VAC2VAC consortium on how to support the deployment of the “Consistency Approach” for quality control of established vaccines and thus facilitate the substitution of in
Autor:
Maxime Vermeulen, Isabelle Feck, Antoine Francotte, Laura Hassall, Lorenzo Tesolin, Wim Van Molle, Romain Pizzato, Thierry Laurent, Charline Hoebreck, Paul Stickings, Alexandre Dobly
Publikováno v:
Journal of Immunological Methods. 517:113483
Autor:
Robert A Johnson, Nele Berthels, Marc Baay, Adrian Wildfire, Volker Oeppling, Sarah M. Fortune, Isabelle Bekeredjian-Ding, Angela van Diepen, Christoph Conrad, Kawsar R. Talaat, Scott Stibitz, Peter G. Kremsner, Wolfram G. Metzger, Karen Brigitta Goetz, Wim Van Molle, Pieter Neels, Stephen J. Thomas, Yves Levy, Daniel F. Hoft, Beno Nyam Yakubu, Andrew Gorringe, Oleg Krut
Publikováno v:
Biologicals. 66:53-61
Controlled human infection models can be helpful to study pathogenesis and immune responses as a basis for the development of vaccines. In controlled human infection models, human challenge agents are used to infect healthy volunteers, therefore, eth
Autor:
Marc Baay, Pieter Neels, Paula Salmikangas, Carine La, Jeffrey M. Bethony, Isabelle Bekeredjian-Ding, Eric Karikari-Boateng, Alan W. Bell, Pauline Meij, Alex Mann, Winfred Badanga Nazziwa, Akamol E. Suvarnapunya, Linda Schellhaas, Jean-Hugues Trouvin, Hilde Depraetere, Wim Van Molle, Dean Smith, Peter Stjärnkvist, Jetsumon Prachumsri
Publikováno v:
Biologicals, 74:16-23
Biologicals, 74, 16-23. ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD
Biologicals, 74, 16-23. ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD
There is an increasing need to establish quality principles for designing, developing and manufacturing challenge agents as currently these agents are classified differently by various jurisdictions. Indeed, considerations for challenge agent manufac
Autor:
Claude Libert, Wim Van Molle
Publikováno v:
European Journal of Immunology. 35:3396-3399
The very powerful anti-inflammatory properties of glucocorticoids (GC) have enabled researchers to use them to treat a variety of inflammatory and autoimmune diseases. The potential of GC lies in their ability to inhibit the production of pro-inflamm
Autor:
Anje Cauwels, Bart Everaerdt, Wim Van Molle, Paul L. Huang, Ben J. A. Janssen, Peter Brouckaert, Walter Fiers
Publikováno v:
Immunity. 13(2):223-231
Hypotension and shock observed in sepsis, SIRS, and tumor necrosis factor (TNF) or cytokine-based cancer treatment are the consequence of excessive nitric oxide (NO) production and subsequent soluble guanylate cyclase (sGC)-mediated vascular smooth m
Autor:
Claude Libert, Bernardo Grijalba, Wim Van Molle, Elisabeth Kremmer, Peter Brouckaert, Harvey R Colten, Ben Wielockx, Walter Fiers
Publikováno v:
Cytokine. 11:617-625
Injection of tumour necrosis factor (TNF) in animals causes severe liver cell toxicity, especially when D-(+)-galactosamine (GalN) is co-administered. After challenge with TNF/GalN, serum complement activity (CH50 and APCH50) decreased dramatically,
Publikováno v:
FEBS Letters. 445:115-118
Experimental hepatitis induced by tumor necrosis factor in d -(+)-galactosamine-sensitized mice or by an agonistic anti-Fas antibody in normal mice is accompanied by dramatic apoptosis of hepatocytes. Apoptosis is the final result of activation of a