Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Wim Th. Kok"'
Autor:
Maria Marioli, Wim Th. Kok
Publikováno v:
Analytical and Bioanalytical Chemistry, 411(11), 2327-2338. Springer Verlag
In asymmetrical flow field-flow fractionation (AF4), similar to other separation techniques, mass recovery and overloading require special attention in order to obtain quantitative results. We conducted a systematic study with five globular proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df47ff52fc0fd2cc59737b2a272154a
https://doi.org/10.1007/s00216-019-01673-w
https://doi.org/10.1007/s00216-019-01673-w
Publikováno v:
Journal of Chromatography A, 1570, 75-81. Elsevier
The current study comprises a systematic investigation to assess retention properties and selectivity of a mixed-mode reversed-phase/weak-anion-exchange (RP/WAX) stationary phase to aid method development. Retention was investigated for different com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8273a35e6016e178aa2205f9d66d839f
https://doi.org/10.1016/j.chroma.2018.07.067
https://doi.org/10.1016/j.chroma.2018.07.067
Publikováno v:
Journal of chromatography A, 1605:360347. Elsevier
In the present proof-of-concept study, we demonstrate that retention time, selectivity and resolution can be increased in asymmetrical flow field-flow fractionation (AF4) by introducing microstructured ultrafiltration membranes. Evenly spaced micron-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff207ba4528f2d8cb909a49320eaf20
https://doi.org/10.1016/j.chroma.2019.07.001
https://doi.org/10.1016/j.chroma.2019.07.001
Autor:
Maria Marioli, Wim Th. Kok
Publikováno v:
Separation and Purification Technology. 242:116744
We present a novel continuous two-dimensional asymmetrical flow field-flow fractionation (2D-AF4) system that is able to fractionate a feed solution of nano-sized solutes (e.g., proteins, nanoparticles) according to their size in aqueous solvents. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::251f670c74f9a3227f103819efebddbc
https://doi.org/10.1016/j.seppur.2020.116744
https://doi.org/10.1016/j.seppur.2020.116744
Autor:
Ben Greijdanus, Marieke G G Sturkenboom, Erwin M Jongedijk, Wim Th. Kok, Henk van der Lijke, Jan-Willem C. Alffenaar, Donald R. A. Uges
Publikováno v:
Journal of Applied Bioanalysis, Vol 1, Iss 3, Pp 89-98 (2015)
Journal of Applied Bioanalysis, 1(3), 89-98
Journal of Applied Bioanalysis, 1(3), 89-98
Clinical studies on tuberculosis have shown a correlation between low drug exposure and treatment failure and acquired drug resistance. Objective was to develop a LC-MS/MS method for the quantification of isoniazid, pyrazinamide and ethambutol. Stabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127a9926135b2edb4025f4f8ebc3ca3a
https://research.rug.nl/en/publications/9c80cdbe-16d0-4ebc-a636-89f435648a95
https://research.rug.nl/en/publications/9c80cdbe-16d0-4ebc-a636-89f435648a95
Autor:
Wim Th. Kok, Bart Devreese, Peter J. Schoenmakers, Catherine Stassen, Dominique J.D. Vanhoutte, Sebastiaan Eeltink, Bert Wouters, Petra Aarnoutse, Adriaan Visser
Publikováno v:
Journal of Chromatography A, 1286, 222-228. Elsevier
The present study concerns the application of visualization methods, i.e. coomassie-brilliant-blue-R staining (CBB-R), silver-nitrate staining, and fluorescamine labeling, and subsequent MALDI-MS analysis of intact proteins and peptides on the surfac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb8e634e7474ba571513df286f08051
https://doi.org/10.1016/j.chroma.2013.02.064
https://doi.org/10.1016/j.chroma.2013.02.064
Publikováno v:
Chromatographia, 75(21-22), 1225-1234. Springer Vieweg
An overview of the literature regarding the most recent and innovative developments in microfluidic devices for pressure-driven chromatographic separations is given, with a focus on proteomics and metabolomics applications. The applications can be co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbf7fe16874bae169d9a7058e9bd68b
https://doi.org/10.1007/s10337-012-2328-z
https://doi.org/10.1007/s10337-012-2328-z
Publikováno v:
Journal of Chromatography A, 1226, 77-86. Elsevier
A new chip-based liquid-liquid extraction technique for sample preparation of aqueous samples for GC was developed. Extraction is performed in a segmented flow system with additional mixing provided by an etched channel structure. The dimensions of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ac742534d241397192176f8d1b826f
https://doi.org/10.1016/j.chroma.2011.08.001
https://doi.org/10.1016/j.chroma.2011.08.001
Publikováno v:
Talanta, 88, 385-390. ELSEVIER SCIENCE BV
Talanta (Oxford), 88, 385-390. Elsevier
Talanta (Oxford), 88, 385-390. Elsevier
A method has been developed for the determination of ribavirin in human serum for therapeutic drug monitoring purposes, using liquid chromatography electrospray ionization mass spectrometry. Separation was obtained with a mobile phase gradient starti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d015500b79828043c64cd37b1c06f5e
https://hdl.handle.net/11370/68a015a6-ba99-4f02-bb7c-d1bdf0f436b8
https://hdl.handle.net/11370/68a015a6-ba99-4f02-bb7c-d1bdf0f436b8
Publikováno v:
Journal of Chromatography A, 1218(31), 5292-5297. Elsevier
Methacrylate monolithic stationary phases were produced in fused-silica chips by UV initiation. Poly(butyl methacrylate-co-ethylene dimethacrylate) (BMA) and poly(lauryl methacrylate-co-ethylene dimethacrylate) (LMA) monoliths containing 30, 35 and 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bca1f60dba8f56a2e004e86758c88c
https://doi.org/10.1016/j.chroma.2011.06.046
https://doi.org/10.1016/j.chroma.2011.06.046