Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Wim J. M. van de Ven"'
Autor:
Almas R. Juma, Sylvia V. H. Grommen, Moira K. O’Bryan, Anne E. O’Connor, D. Jo Merriner, Nathan E. Hall, Stephen R. Doyle, Pauliina E. Damdimopoulou, Daniel Barriga, Adam H. Hart, Wim J. M. Van de Ven, Bert De Groef
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Deficiency in pleomorphic adenoma gene 1 (PLAG1) leads to reduced fertility in male mice, but the mechanism by which PLAG1 contributes to reproduction is unknown. To investigate the involvement of PLAG1 in testicular function, we determined
Externí odkaz:
https://doaj.org/article/f9a9c5dca672498dbf31f37666823195
Autor:
Jeroen Declercq, Anujith Kumar, Conny Gysemans, Caterina Di Pietro, Anica Schraenen, Marie Chintinne, Katleen Lemaire, Leentje Van Lommel, Marc Van De Casteele, Harry Heimberg, Daniel Pipeleers, Frans C. Schuit, Chantal Mathieu, Nadine Ectors, Wim J. M. Van De Ven, Catherine M. Verfaillie
Publikováno v:
Cell Transplantation, Vol 20 (2011)
Pleomorphic adenoma gene-like 1 (PLAGL1) has been linked to transient neonatal diabetes mellitus. Here, we investigated the role of the related pleomorphic adenoma gene 1 (PLAG1) in glucose homeostasis. PLAG1 transgenic mice in which expression of th
Externí odkaz:
https://doaj.org/article/17addc0241c84f30bbbcabd07b44cc64
Autor:
Xu Chao, Zhuoli Zhang, Lili Guo, Jingjing Zhu, Mingli Peng, Alphonsus J M Vermorken, Wim J M Van de Ven, Chao Chen, Yali Cui
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e40388 (2012)
BACKGROUND: Magnetic nanoparticles (NPs) loaded with antitumor drugs in combination with an external magnetic field (EMF)-guided delivery can improve the efficacy of treatment and may decrease serious side effects. The purpose of this study was 1) to
Externí odkaz:
https://doaj.org/article/f13d8a67a9f54b208afb4802598d3d54
Autor:
Frederik, Van Dyck, Ilse, Scroyen, Jeroen, Declercq, Raf, Sciot, Barbara, Kahn, Roger, Lijnen, Wim J M, Van de Ven
Publikováno v:
International journal of oncology. 32(1)
The developmentally regulated PLAG1 proto-oncogene has been implicated in the development of various human tumor types, such as pleomorphic salivary gland adenomas, lipoblastomas, hepatoblastomas and AML. In previous studies, we generated two indepen
Publikováno v:
International journal of oncology. 30(4)
Recent studies of human tumours as well as genetically engineered mouse tumour models have established the importance and versatility of the PLAG1 oncogene in tumourigenesis. The PLAG1 proto-oncogene was discovered by studying the t(3;8)(p21;q12) chr
Autor:
Marleen M R, Petit, Sandra M P, Meulemans, Philippe, Alen, Torik A Y, Ayoubi, Erik, Jansen, Wim J M, Van de Ven
Publikováno v:
BMC Cell Biology
Background At sites of cell adhesion, proteins exist that not only perform structural tasks but also have a signaling function. Previously, we found that the Lipoma Preferred Partner (LPP) protein is localized at sites of cell adhesion such as focal
Autor:
Karen, Hensen, Isabelle C C, Van Valckenborgh, Koen, Kas, Wim J M, Van de Ven, Marianne L, Voz
Publikováno v:
Cancer research. 62(5)
Pleomorphic adenoma gene (PLAG) 1, the main translocation target in pleomorphic adenomas of the salivary glands, is a member of a new subfamily of zinc finger proteins comprising the tumor suppressor candidate PLAG-like1 (also called ZAC1 or lost on
Abelson murine leukaemia virus transformation involves loss of epidermal growth factor-binding sites
Publikováno v:
Nature. 286:504-507
Malignant transformation by mammalian RNA sarcoma viruses has previously been shown to involve a reduction in receptor sites for a well characterized 6,000-molecular weight (MW) growth-promoting substance, designated epidermal growth factor (EGF). Al
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Autor:
Everardus J. J. van Zoelen, Wim J. M. van de Ven, Henk J. Franssen, Theodora M. J. van Oostwaard, Paul T. van der Saag, Carl-Henrik Heldin, Siegfried W. de Laat
Publikováno v:
Molecular and cellular biology. 5(9)
Mouse neuroblastoma Neuro-2A cells produce transforming growth factors during exponential growth in a defined hormone-free medium, which, on Bio-Gel columns in 1 M HAc, elute at a molecular size of 15 to 20 kilodaltons (kDa). These neuroblastoma-deri