Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Wim J. Klaver"'
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 105:299-306
Alkylation of the lithium enolate, derived from 5-ethoxy-2-pyrrolidone 1 (Scheme 1), using alkyl halides containing either the vinylsilane or 2-propynylsilane moiety, provides substrates 3 for cyclization studies passing through N-acyliminium interme
Publikováno v:
Tetrahedron Letters. 28:1581-1584
The alkylation of the dianion of the title compound ( 2 ) readily prepared from (S)-malic acid, with ω-iodo-1-trimethylsilyl-2-alkynes ( 8a - c ) occurs with high trans-selectivity with respect to the hydroxyl function. The products ( 11a - c ) cycl
Publikováno v:
Tetrahedron Letters. 25:5453-5456
The combination of a silicon directed N-acyliminium ion cyclization reaction and a subsequent S N 2′ substitution of an imide nitrogen with lithium dimethyl cuprate constitutes a novel approach to functionalized transfused carbobicycles.
Publikováno v:
Tetrahedron. 44:3805-3818
Intramolecular acid-assisted reactions of 2-propynylsilanes with cyclic N -acyliminium ion precursors lead to bridged azabicyclic systems 34 – 45 (Table I), containing the uncommon α-allenic amide functionality. After introduction of a tert -butox
Autor:
Wim J. Klaver, M.Robert P. Van Vliet, Caspar H. Stam, Gerard van Koten, Kees Goubitz, J.F. Modder, Johannus A. M. van Beek
Publikováno v:
Journal of Organometallic Chemistry. 319:285-301
Reactions of ZnCl 2 and AlCl 3 with 3-substituted 1-aza-4-oxo-1,3-butadienes (α-iminoesters and amides) have given the corresponding 1:1 complexes MCl n [(t-Bu)NCHC(R 3 )O] (R 3 = OMe, OEt or NEt 2 ). The α-iminoester and amide ligands in the
Publikováno v:
Tetrahedron. 44:6729-6738
Intramolecular acid-mediated reactions of 2-propynyl- and allylsilanes with five- and six-membered cyclic N-acyliminium ion precursors lead to bridged azabicyclic compounds (Table I). Neat formic acid is the reaction medium of choice in most cases. T
Publikováno v:
Journal of the American Chemical Society. 111:2588-2595
Autor:
Gerard van Koten, Wim J. Klaver, Kees Goubitz, M.Robert P. Van Vliet, Johann T. B. H. Jastrzebski
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 106:132-134
Reaction of iminoesters, RNC(H)COOR′, (R tBu, i-Pr; R′ Me, Et) with diethylzinc affords in a selective quantitative reaction trans-β-lactams. An X-ray crystal structure determination of the obtained trans-1-(N-t-butyl-3-(N-t-butyl-N-ethylamino)-
Publikováno v:
The Journal of Organic Chemistry. 49:1149-1151
L'alkylation des enolates de lithium derives d'alcoxy-5 pyrrolidones-2 ou ethoxy-6 piperidones-2 par des iodures insatures conduit aux produits alkyles en 3. Les produits alkyles contenant une partie allyl ou propargyl silane se cyclisent en presence
Publikováno v:
ChemInform. 18