Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Wim J. Quax"'
Autor:
Yafeng Song, Huizhong Liu, Wim J. Quax, Zhiqing Zhang, Yiwen Chen, Ping Yang, Yinhua Cui, Qingshan Shi, Xiaobao Xie
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Valencene, a sesquiterpene with the odor of sweet and fresh citrus, is widely used in the food, beverage, flavor and fragrance industry. Valencene is traditionally obtained from citrus fruits, which possess low concentrations of this compound. In the
Externí odkaz:
https://doaj.org/article/bee804a4a0874851b55281701c1e6101
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype independent of estrogen receptor, progesterone receptor, or human epidermal growth factor receptor 2. It has a poor prognosis and high recurrence. Due to its limited tr
Externí odkaz:
https://doaj.org/article/200ae127c7814f298c222918336733bd
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The bioprospecting of secondary metabolites from endophytic fungi received great attention in the 1990s and 2000s, when the controversy around taxol production from Taxus spp. endophytes was at its height. Since then, hundreds of reports have describ
Externí odkaz:
https://doaj.org/article/8fdae1b29b0d44b4a270599ef0e095ff
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 395 (2022)
Artemisinin, the most famous anti-malaria drug initially extracted from Artemisia annua L., also exhibits anti-tumor properties in vivo and in vitro. To improve its solubility and bioavailability, multiple derivatives have been synthesized. However,
Externí odkaz:
https://doaj.org/article/df0908cd07aa47878960eb001c5ff4d9
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Tumor necrosis factor–related apoptosis inducing ligand (TRAIL) is considered to be a promising antitumor drug because of its selective proapoptotic properties on tumor cells. However, the clinical application of TRAIL is until now limited because
Externí odkaz:
https://doaj.org/article/97c0f6c280154b58be4462dff5229991
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The bacterial biofilm plays a key role in nosocomial infections, especially those related to medical devices in sustained contact with patients. The active dispersion of bacterial cells out of biofilms acts as a reservoir for infectious diseases. The
Externí odkaz:
https://doaj.org/article/3cb289373f5c432195d3ca33c10712d3
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 170 (2022)
The opportunistic pathogen Pseudomonas aeruginosa employs quorum sensing to govern the production of many virulence factors. Interference with quorum sensing signaling has therefore been put forward as an attractive approach to disarm this pathogen.
Externí odkaz:
https://doaj.org/article/6a66896ff72e4651817c2bc20ce6840b
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 181 (2022)
The tumor necrosis factor (TNF) ligand family has nine ligands that show promiscuity in binding multiple receptors. As different receptors transduce into diverse pathways, the study on the functional role of natural ligands is very complex. In this r
Externí odkaz:
https://doaj.org/article/ddc19af6a4844e899190a5bf2235e72b
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Terpenoids are natural products known for their medicinal and commercial applications. Metabolic engineering of microbial hosts for the production of valuable compounds, such as artemisinin and Taxol, has gained vast interest in the last few decades.
Externí odkaz:
https://doaj.org/article/94d71e8b96464264a959f363f9771697
Publikováno v:
Bioorganic Chemistry, 136:106546
Various diseases are deeply associated with aberrations in HDAC8 functions. These aberrations can be assigned to either structural functions or catalytic functions of HDAC8. Therefore, development of HDAC8 degradation inducers might be more promising