Zobrazeno 1 - 10
of 370
pro vyhledávání: '"Wim B. van den Berg"'
Autor:
Rebecca Rogier, Thomas H. A. Ederveen, Jos Boekhorst, Harm Wopereis, Jose U. Scher, Julia Manasson, Sanne J. C. M. Frambach, Jan Knol, Johan Garssen, Peter M. van der Kraan, Marije I. Koenders, Wim B. van den Berg, Sacha A. F. T. van Hijum, Shahla Abdollahi-Roodsaz
Publikováno v:
Microbiome, Vol 5, Iss 1, Pp 1-15 (2017)
Abstract Background Perturbation of commensal intestinal microbiota has been associated with several autoimmune diseases. Mice deficient in interleukin-1 receptor antagonist (Il1rn −/− mice) spontaneously develop autoimmune arthritis and are susc
Externí odkaz:
https://doaj.org/article/f6f0fd9d2a5841efb5e3dfcd340e757c
Autor:
Mathijs G.A. Broeren, Irene Di Ceglie, Miranda B. Bennink, Peter L.E.M. van Lent, Wim B. van den Berg, Marije I. Koenders, Esmeralda N. Blaney Davidson, Peter M. van der Kraan, Fons A.J. van de Loo
Publikováno v:
PeerJ, Vol 6, p e4771 (2018)
Objective Tumor necrosis factor-inducible gene 6 (TSG-6) has anti-inflammatory and chondroprotective effects in mouse models of inflammatory arthritis. Because cartilage damage and inflammation are also observed in osteoarthritis (OA), we determined
Externí odkaz:
https://doaj.org/article/e674760745904a79b44e5fdbcd6e3d74
Autor:
Claire E. J. Waterborg, Silke Beermann, Mathijs G. A. Broeren, Miranda B. Bennink, Marije I. Koenders, Peter L. E. M. van Lent, Wim B. van den Berg, Peter M. van der Kraan, Fons A. J. van de Loo
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
ObjectiveRheumatoid arthritis (RA) is a chronic and progressive joint disease. It appears that anti-inflammatory feedback mechanisms that could restrain joint inflammation and restore homeostasis are insufficient to perform this control. In this stud
Externí odkaz:
https://doaj.org/article/ca6733155fe54ecab960104d139acfd6
Autor:
Debbie M Roeleveld, Renoud J Marijnissen, Birgitte Walgreen, Monique M Helsen, Liduine van den Bersselaar, Fons A van de Loo, Peter L van Lent, Peter M van der Kraan, Wim B van den Berg, Marije I Koenders
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171757 (2017)
Th17 cells and their cytokines are linked to the pathogenesis of rheumatoid arthritis, a chronic autoimmune disease characterized by joint inflammation. Th17 development is initiated by combined signaling of TGF-β and IL-6 or IL-21, and can be reduc
Externí odkaz:
https://doaj.org/article/78384ac380dc442c8a8468639da74800
Autor:
Bartijn C H Pieters, Onno J Arntz, Miranda B Bennink, Mathijs G A Broeren, Arjan P M van Caam, Marije I Koenders, Peter L E M van Lent, Wim B van den Berg, Marieke de Vries, Peter M van der Kraan, Fons A J van de Loo
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121123 (2015)
ScopeExtracellular vesicles, including exosomes, have been identified in all biological fluids and rediscovered as an important part of the intercellular communication. Breast milk also contains extracellular vesicles and the proposed biological func
Externí odkaz:
https://doaj.org/article/f09e52a2843b43f2bebd39101869033a
Autor:
Eline A Vermeij, Marije I Koenders, Miranda B Bennink, Lindsey A Crowe, Lionel Maurizi, Jean-Paul Vallée, Heinrich Hofmann, Wim B van den Berg, Peter L E M van Lent, Fons A J van de Loo
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126687 (2015)
Superparamagnetic Iron Oxide Nanoparticles (SPION) are used in diagnostic imaging of a variety of different diseases. For such in-vivo application, an additional coating with a polymer, for example polyvinyl alcohol (PVA), is needed to stabilize the
Externí odkaz:
https://doaj.org/article/65221a7ed41b49c39dfa59621959c74c
Autor:
Eline A. Vermeij, Marije I. Koenders, Arjen B. Blom, Onno J. Arntz, Miranda B. Bennink, Wim B. van den Berg, Peter L.E.M. van Lent, Fons A.J. van de Loo
Publikováno v:
Molecular Imaging, Vol 13 (2014)
Rheumatoid arthritis (RA) and osteoarthritis (OA) are serologically and clinically distinctive, but at the local level, both diseases have many molecular pathways in common. In vivo molecular imaging can unravel the local pathologic processes involve
Externí odkaz:
https://doaj.org/article/28070d24be67493c9d7e39c91239ac85
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110966 (2014)
In rheumatoid arthritis (RA) macrophages play a major role in amplifying synovial inflammation. Important activating signals are those induced by Toll-like receptor (TLR) ligands and by activated T cells. The balance between activating and inhibitory
Externí odkaz:
https://doaj.org/article/97205cfaa86f48e29bd01545fc30a961
Autor:
Ben T van den Brand, Eline A Vermeij, Claire E J Waterborg, Onno J Arntz, Michael Kracht, Miranda B Bennink, Wim B van den Berg, Fons A J van de Loo
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55356 (2013)
Antigen presenting cells (APCs) play an important role in arthritis and APC specific gene therapeutic targeting will enable intracellular modulation of cell activity. Viral mediated overexpression is a potent approach to achieve adequate transgene ex
Externí odkaz:
https://doaj.org/article/f8f3c983bdd84b77975d3261d594c08e
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54016 (2013)
BACKGROUND: To determine the effects of liposomal targeting of prednisolone phosphate (Lip-PLP) to synovial lining macrophages on M1 and M2 polarization in vitro and during experimental arthritis. MATERIAL AND METHODS: Experimental arthritis (antigen
Externí odkaz:
https://doaj.org/article/4ac0fe0b07424525b2a61d62bc5dafcc