Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Wim, Vranken"'
Autor:
Liselot Dewachter, Aaron N. Brooks, Katherine Noon, Charlotte Cialek, Alia Clark-ElSayed, Thomas Schalck, Nandini Krishnamurthy, Wim Versées, Wim Vranken, Jan Michiels
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Deep mutational scanning can be used to investigate protein function and stability. Here, Dewachter et al. use deep mutational scanning on three essential bacterial proteins to study the mutations’ effects in their original genomic context, providi
Externí odkaz:
https://doaj.org/article/32c3951dd8e34dadbbb42bed12452929
Autor:
R. Anahí Higuera-Rodriguez, Jose Gavaldá-García, Joel Roca Martínez, Anna Kravchenko, Anna Pérez-Ràfols, Niki Messini, Luca Sperotto, Guillermo Pérez Ropero, Wim Vranken, Isaure Chauvot de Beauchêne, Malika Smaïl-Tabbone, Marie-Dominique Devignes, Roswitha Dolcemascolo, Hrishikesh Dhondge
Publikováno v:
Open Research Europe, Vol 3 (2023)
Background: Data management is fast becoming an essential part of scientific practice, driven by open science and FAIR (findable, accessible, interoperable, and reusable) data sharing requirements. Whilst data management plans (DMPs) are clear to dat
Externí odkaz:
https://doaj.org/article/73eea1d6b306467e96567818d77c5b5c
Autor:
Morgane Boone, Pathmanaban Ramasamy, Jasper Zuallaert, Robbin Bouwmeester, Berre Van Moer, Davy Maddelein, Demet Turan, Niels Hulstaert, Hannah Eeckhaut, Elien Vandermarliere, Lennart Martens, Sven Degroeve, Wesley De Neve, Wim Vranken, Nico Callewaert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The exact protein features that control passage through the eukaryotic secretory system remain largely unknown. Here the authors report SECRiFY which they use to evaluate the secretory potential of polypeptides on a proteome-wide scale in yeast, reve
Externí odkaz:
https://doaj.org/article/043a1799d9594a9ab4b4cd01c3c5aabe
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4919-4930 (2021)
Protein folding and function are closely connected, but the exact mechanisms by which proteins fold remain elusive. Early folding residues (EFRs) are amino acids within a particular protein that induce the very first stages of the folding process. Hi
Externí odkaz:
https://doaj.org/article/bc4b65949a274a9c9eef1b17ca08bf1a
Autor:
Morgane Boone, Pathmanaban Ramasamy, Jasper Zuallaert, Robbin Bouwmeester, Berre Van Moer, Davy Maddelein, Demet Turan, Niels Hulstaert, Hannah Eeckhaut, Elien Vandermarliere, Lennart Martens, Sven Degroeve, Wesley De Neve, Wim Vranken, Nico Callewaert
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/59e221e1945e465da5a2c8878e6d8f64
Autor:
Liselot Dewachter, Aaron N. Brooks, Katherine Noon, Charlotte Cialek, Alia Clark-ElSayed, Thomas Schalck, Nandini Krishnamurthy, Wim Versées, Wim Vranken, Jan Michiels
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/ff608562e056407fa9c719bd2a329b2c
Autor:
Maria S. Loos, Reshmi Ramakrishnan, Wim Vranken, Alexandra Tsirigotaki, Evrydiki-Pandora Tsare, Valentina Zorzini, Jozefien De Geyter, Biao Yuan, Ioannis Tsamardinos, Maria Klappa, Joost Schymkowitz, Frederic Rousseau, Spyridoula Karamanou, Anastassios Economou
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Cellular proteomes are distributed in multiple compartments: on DNA, ribosomes, on and inside membranes, or they become secreted. Structural properties that allow polypeptides to occupy subcellular niches, particularly to after crossing membranes, re
Externí odkaz:
https://doaj.org/article/f964f2cc62aa4fb49f3c6eb9921c6033
Autor:
Borja Alonso-Lerma, Ylenia Jabalera, Sara Samperio, Matias Morin, Almudena Fernandez, Logan T. Hille, Rachel A. Silverstein, Ane Quesada-Ganuza, Antonio Reifs, Sergio Fernández-Peñalver, Yolanda Benitez, Lucia Soletto, Jose A. Gavira, Adrian Diaz, Wim Vranken, Avencia Sanchez-Mejias, Marc Güell, Francisco J. M. Mojica, Benjamin P. Kleinstiver, Miguel A. Moreno-Pelayo, Lluis Montoliu, Raul Perez-Jimenez
Publikováno v:
Nat Microbiol
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9 is an effector protein that targets invading DNA and plays a major role in the prokaryotic adaptive immune system. Although Streptococcus pyogenes CRISPR–Cas9 has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53d8df2c46392fb5741544f0f76fd3d
https://doi.org/10.1038/s41564-022-01265-y
https://doi.org/10.1038/s41564-022-01265-y
Autor:
Dries Smets, Alexandra Tsirigotaki, Jochem H Smit, Srinath Krishnamurthy, Athina G Portaliou, Anastassia Vorobieva, Wim Vranken, Spyridoula Karamanou, Anastassios Economou
Secretory preproteins of the Sec pathway are targeted post-translationally and cross cellular membranes through translocases. During cytoplasmic transit, mature domains remain non-folded for translocase recognition/translocation. After translocation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5864da46789a9a80208e8e6ffd39962
https://doi.org/10.15252/embj.2022111344
https://doi.org/10.15252/embj.2022111344
Autor:
Bálint Mészáros, András Hatos, Nicolas Palopoli, Federica Quaglia, Edoardo Salladini, Kim Van Roey, Haribabu Arthanari, Zsuzsanna Dosztányi, Isabella C. Felli, Patrick D Fischer, Jeffrey C. Hoch, Cy M Jeffries, Sonia Longhi, Emiliano Maiani, Sandra Orchard, Rita Pancsa, Elena Papaleo, Roberta Pierattelli, Damiano Piovesan, Iva Pritisanac, Thibault Viennet, Peter Tompa, Wim Vranken, Silvio CE Tosatto, Norman E Davey
An unambiguous description of an experimental setup and analysis, and the subsequent biological observation is vital for accurate data interpretation and reproducible results. Consequently, experimental analyses should be described in a concise, uneq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21f49f4a10a13805abedf2e351f974a8
https://doi.org/10.1101/2022.07.12.495092
https://doi.org/10.1101/2022.07.12.495092