Stability Indicating Method for Determination of Benznidazole and Its Degradation Products in Active Pharmaceutical Ingredient

Autor: Michel Leandro Campos, Roberto Pontarolo, Iara J. Messias Reason, Letícia Bonancio Cerqueira, Mariana Millan Fachi, Wilton H. Kawaguchi, Angela C. L. B. Trindade, Alan G. Gonçalves

Publikováno v: Journal of the Brazilian Chemical Society v.31 n.6 2020
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 31, Issue: 6, Pages: 1194-1202, Published: 08 JUN 2020

Currently, treatment of Chagas disease is restricted to the use of benznidazole and nifurtimox; however, nifurtimox was temporarily suspended in some countries. Based on the limitations in pharmacological treatments, it is essential to guarantee the

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