Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Wilson PH"'
Autor:
Gantet, C, Wilson, PH
Publikováno v:
Dix-septième siècle. :225-251
La guerre de Trente Ans (1618-1648) fut plus souvent ponctuée de batailles que les historiens ne l’ont longtemps présumé. On dénombre en effet 48 batailles moyennes et grandes par les effectifs engagés, de 7 000 à 89 000 soldats. Or, loin de
Autor:
Luis F. Schachner, Christopher Mullen, Wilson Phung, Joshua D. Hinkle, Michelle Irwin Beardsley, Tracy Bentley, Peter Day, Christina Tsai, Siddharth Sukumaran, Tomasz Baginski, Danielle DiCara, Nicholas J. Agard, Matthieu Masureel, Joshua Gober, Adel M. ElSohly, Rafael Melani, John E. P. Syka, Romain Huguet, Michael T. Marty, Wendy Sandoval
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The heterogeneity inherent in today’s biotherapeutics, especially as a result of heavy glycosylation, can affect a molecule’s safety and efficacy. Characterizing this heterogeneity is crucial for drug development and quality assessment,
Externí odkaz:
https://doaj.org/article/1f51a60ae7254824a781e70ff1592428
Autor:
Wilson, PH
Our understanding of the Holy roman empire has been transformed in the last fifty years. the older, ‘Borussian interpretation’ dismissed the empire in its last two centuries as moribund and doomed to be supplanted by dynamic, centralizing ‘powe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::27d4022fb919ecc2f4a8e981bc19bfa3
https://ora.ox.ac.uk/objects/uuid:afd2cab0-de36-4292-86eb-5298ade47695
https://ora.ox.ac.uk/objects/uuid:afd2cab0-de36-4292-86eb-5298ade47695
Autor:
Elizabeth Sara Hecht, Shrenik Mehta, Aaron T. Wecksler, Ben Aguilar, Nathaniel Swanson, Wilson Phung, Ananya Dubey Kelsoe, W. Henry Benner, Devin Tesar, Robert F. Kelley, Wendy Sandoval, Alavattam Sreedhara
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Detection of host cell protein (HCP) impurities is critical to ensuring that recombinant drug products, including monoclonal antibodies (mAbs), are safe. Mechanistic characterization as to how HCPs persist in drug products is important to refining do
Externí odkaz:
https://doaj.org/article/d0847215cccc4d5da45d73cb8db4ce8f
Autor:
Elena Ferri, Adrien Le Thomas, Heidi Ackerly Wallweber, Eric S. Day, Benjamin T. Walters, Susan E. Kaufman, Marie-Gabrielle Braun, Kevin R. Clark, Maureen H. Beresini, Kyle Mortara, Yung-Chia A. Chen, Breanna Canter, Wilson Phung, Peter S. Liu, Alfred Lammens, Avi Ashkenazi, Joachim Rudolph, Weiru Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The RNase activity of Inositol-Requiring Enzyme 1 (IRE1) can be allosterically regulated by ATP-competitive inhibitors of the IRE1 kinase domain. Here, the authors identify ATP-competitive IRE1 RNase activators with improved selectivity and cellular
Externí odkaz:
https://doaj.org/article/b949b998bea04b119070c87d6eced201
Autor:
Kamal Kishore Joshi, Wilson Phung, Guanghui Han, Yiyuan Yin, Ingrid Kim, Wendy Sandoval, Paul J. Carter
Publikováno v:
mAbs, Vol 11, Iss 7, Pp 1254-1265 (2019)
Multiple strategies have been developed to facilitate the efficient production of bispecific IgG (BsIgG) in single host cells. For example, we previously demonstrated near quantitative (≥90%) formation of BsIgG of different species and isotypes by
Externí odkaz:
https://doaj.org/article/0b0701cfc3784dc08be1e7b2752abc7e
Autor:
Bingchuan Wei, Xuan Gao, Lance Cadang, Saeed Izadi, Peilu Liu, Hui-Min Zhang, Elizabeth Hecht, Jeongsup Shim, Gordon Magill, Juan Rincon Pabon, Lu Dai, Wilson Phung, Elaine Lin, Christopher Wang, Kevin Whang, Sean Sanchez, Jose Oropeza Jr, Julien Camperi, Jennifer Zhang, Wendy Sandoval, Yonghua Taylor Zhang, Guoying Jiang
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Fc galactosylation is a critical quality attribute for anti-tumor recombinant immunoglobulin G (IgG)-based monoclonal antibody (mAb) therapeutics with complement-dependent cytotoxicity (CDC) as the mechanism of action. Although the correlation betwee
Externí odkaz:
https://doaj.org/article/bdd3b615610e438ebfe86ec19cb0df05
Publikováno v:
International Journal of Language & Communication Disorders. Jul-Sep2005, Vol. 40 Issue 3, p319-332. 14p.
Autor:
Wilson Phung, Guanghui Han, Stéphanie G.I. Polderdijk, Michael Dillon, Whitney Shatz, Peter Liu, Bingchuan Wei, Pawankumar Suresh, David Fischer, Christoph Spiess, Aaron Bailey, Paul J. Carter, Jennie R. Lill, Wendy Sandoval
Publikováno v:
Data in Brief, Vol 30, Iss , Pp 105435- (2020)
The data supplied in this work are related to the research article entitled “Characterization of Bispecific and Mispaired IgGs by Native Charge-Variant Mass Spectrometry” (Phung et al., 2019). This data article describes a powerful analytical pla
Externí odkaz:
https://doaj.org/article/3d70c2e23d894d29be80278d6eb3b339
Autor:
Yvonne Chen, Maciej Paluch, Julie A. Zorn, Sharmila Rajan, Brandon Leonard, Alberto Estevez, John Brady, Henry Chiu, Wilson Phung, Amin Famili, Minhong Yan, Claudio Ciferri, Marissa L. Matsumoto, Greg A. Lazar, Susan Crowell, Phil Hass, Nicholas J. Agard
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Treatment of ocular disease is hindered by the presence of the blood-retinal barrier, which restricts access of systemic drugs to the eye. Intravitreal injections bypass this barrier, delivering high concentrations of drug to the targeted tissue. How
Externí odkaz:
https://doaj.org/article/28ad3cfcdaf4459abab263005b66f32a