Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Wilson C J Chung"'
Autor:
Megan L Linscott, Wilson C J Chung
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220530 (2019)
Fibroblast growth factor 8 (FGF8) is a potent morphogen that regulates the ontogenesis of gonadotropin-releasing hormone (GnRH) neurons, which control the hypothalamus-pituitary-gonadal (HPG) axis, and therefore reproductive success. Indeed, FGF8 and
Externí odkaz:
https://doaj.org/article/4f8bc970e09e41b3b9d3639fe44af7cb
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10143 (2010)
Fibroblast growth factors (FGFs) mediate a vast range of CNS developmental processes including neural induction, proliferation, migration, and cell survival. Despite the critical role of FGF signaling for normal CNS development, few reports describe
Externí odkaz:
https://doaj.org/article/c7261d22bc0a45f988a4cc2f5c3ff080
Publikováno v:
Endocrinology
The rapid decline of circulating 17β-estradiol (E2) at menopause leads to negative neurological consequences, although hormone therapy paradoxically has both harmful and positive effects depending on the age at which it is delivered. The inconsisten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ac02dc1d6266893369d902fc40e79e
https://pubmed.ncbi.nlm.nih.gov/34147032
https://pubmed.ncbi.nlm.nih.gov/34147032
Autor:
Wilson C. J. Chung, Megan L. Linscott
Publikováno v:
Journal of Neuroendocrinology. 32
Mammalian reproductive success depends on gonadotrophin-releasing hormone (GnRH) neurones to stimulate gonadotrophin secretion from the anterior pituitary and activate gonadal steroidogenesis and gametogenesis. Genetic screening studies in patients d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973b26c5cabc35f6f1785977accee1e1
https://doi.org/10.1111/jne.12860
https://doi.org/10.1111/jne.12860
Publikováno v:
Neuroscience letters. 714
Down syndrome is the most common genetic cause of intellectual disability and occurs due to the trisomy of human chromosome 21. Adolescent and adult brains from humans with Down syndrome exhibit various neurological phenotypes including a reduction i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e0db4fd859cb2be1a907ea18b9c52f
https://pubmed.ncbi.nlm.nih.gov/31644920
https://pubmed.ncbi.nlm.nih.gov/31644920
Autor:
Wilson C. J. Chung, Robert J. Handa
An increasing number of sex differences in neuroendocrine, autonomic, or behavioral responses to stress have been reported in the research literature over the past several decades. Many studies used animal models to demonstrate hormonal and behaviora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817b6b8ab7ae7375995acbcf8192dcce
https://doi.org/10.1016/b978-0-12-813146-6.00014-x
https://doi.org/10.1016/b978-0-12-813146-6.00014-x
Publikováno v:
Journal of neuroendocrinology. 30(2)
Estrogen receptor beta (ERβ) is a multifunctional nuclear receptor that mediates the actions of estrogenic compounds. Despite its well defined role in mediating the actions of estrogens, a substantial body of evidence demonstrates that ERβ has broa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c4d407a998bc26091154e697ab04b0
https://pubmed.ncbi.nlm.nih.gov/28514502
https://pubmed.ncbi.nlm.nih.gov/28514502
Autor:
Wilson C. J. Chung, Anthony P. Auger
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 465:573-584
The concept that the brain differs in make-up between males and females is not new. For example, it is well-established that anatomists in the nineteenth century found sex differences in human brain weight. The importance of sex differences in the or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c272605b54336989935ffa539fd2c4f
https://doi.org/10.1007/s00424-013-1258-4
https://doi.org/10.1007/s00424-013-1258-4
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 7 (2016)
Frontiers in Endocrinology, Vol 7 (2016)
Over the last few years, numerous studies solidified the hypothesis that fibroblast growth factor (FGF) signaling regulates neuroendocrine progenitor cell proliferation, fate-specification, and cell survival, and therefore is critical for the regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8225999f2558382d03c7846c306d1de7
https://pubmed.ncbi.nlm.nih.gov/27656162
https://pubmed.ncbi.nlm.nih.gov/27656162
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 303:E1428-E1439
The continued presence of gonadotropin-releasing hormone (GnRH) neurons is required for a healthy reproductive lifespan, but factors that maintain postnatal GnRH neurons have not been identified. To begin to understand these factors, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09307435d78ea44b800a2b9573335b50
https://doi.org/10.1152/ajpendo.00289.2012
https://doi.org/10.1152/ajpendo.00289.2012