Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Wilmar Dias da Silva"'
Autor:
Carlos Alberto-Silva, Brenda Rufino da Silva, Julio Cezar Araujo da Silva, Felipe Assumpção da Cunha e Silva, Roberto Tadashi Kodama, Wilmar Dias da Silva, Maricilia Silva Costa, Fernanda Calheta Vieira Portaro
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 931 (2024)
Introduction. The proline-rich decapeptide 10c (Bj-PRO-10c; ENWPHPQIPP) from the Bothrops jararaca snake modulates argininosuccinate synthetase (AsS) activity to stimulate L-arginine metabolite production and neuroprotection in the SH-SY5Y cell line.
Externí odkaz:
https://doaj.org/article/d77ba269d255466886100020b047923b
Autor:
Lucas Yuri Saladini, Marcos Jorge Magalhães-Junior, Cristiane Castilho Fernandes da Silva, Priscila Gonçalves Coutinho Oliveira, Roberto Tadashi Kodama, Lais Gomes, Milton Yutaka Nishiyama-Jr, Patrick Jack Spencer, Wilmar Dias da Silva, Fernanda Calheta Vieira Portaro
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5181 (2024)
Snakebite accidents, neglected tropical diseases per the WHO, pose a significant public health threat due to their severity and frequency. Envenomation by Bothrops genus snakes leads to severe manifestations due to proteolytic enzymes. While the anti
Externí odkaz:
https://doaj.org/article/a025de9c610243a3b862f150a2153a38
Autor:
Felipe Raimondi Guidolin, Kemily Stephanie de Godoi, Angela Alice Amadeu Megale, Cristiane Castilho Fernandes da Silva, Roberto Tadashi Kodama, Daniela Cajado-Carvalho, Leo Kei Iwai, Patrick Jack Spencer, Fernanda Calheta Vieira Portaro, Wilmar Dias da Silva
Publikováno v:
Toxins, Vol 15, Iss 9, p 584 (2023)
Accidents with snakes are responsible for about 32,000 deaths annually in sub-Saharan Africa, caused mostly by snakes from the genus Bitis, in particular Bitis arietans. B. arietans venom is composed of a complex mixture of toxins, mainly metalloprot
Externí odkaz:
https://doaj.org/article/0e60d8ffdb78430f90d2ff59203e729d
Autor:
Kemily Stephanie de Godoi, Felipe Raimondi Guidolin, Fernanda Calheta Vieira Portaro, Patrick Jack Spencer, Wilmar Dias da Silva
Publikováno v:
Toxins, Vol 15, Iss 4, p 264 (2023)
Bitis arietans is a medically important snake found in Sub-Saharan Africa. The envenomation is characterized by local and systemic effects, and the lack of antivenoms aggravates the treatment. This study aimed to identify venom toxins and develop ant
Externí odkaz:
https://doaj.org/article/79a087c8001e4116b6ed9655e388f7ef
Autor:
Luciana Regina Pereira Oliveira, Lívia Mattos Martins, Rebeka da Conceição Souza, Yuri Scheidegger de Castro, Letícia Silva Nascimento, Juliana Azevedo da Silva, Edilbert Pellegrini Nahn Junior, Wilmar Dias da Silva, Alba Lucínia Peixoto-Rangel
Publikováno v:
Infectious Diseases of Poverty, Vol 9, Iss 1, Pp 1-10 (2020)
Abstract Background Mycobacterium leprae and Toxoplasma gondii infections are both neglected tropical diseases highly prevalent in Brazil. Infection with certain parasite species can significantly alter susceptibility to other important pathogens, an
Externí odkaz:
https://doaj.org/article/ed1f07b2823f47c5ba78d560c1502ac1
Autor:
Wilmar Dias da Silva, Sonia A. De Andrade, Ângela Alice Amadeu Megale, Daniel Alexandre De Souza, Osvaldo Augusto Sant’Anna, Fábio Carlos Magnoli, Felipe Raimondi Guidolin, Kemily Stephanie Godoi, Lucas Yuri Saladini, Patrick Jack Spencer, Fernanda Calheta Vieira Portaro
Publikováno v:
Toxins, Vol 14, Iss 9, p 606 (2022)
Snakebite envenomation is considered a neglected tropical disease, affecting tens of thousands of people each year. The recommended treatment is the use of antivenom, which is composed of immunoglobulins or immunoglobulin fragments obtained from the
Externí odkaz:
https://doaj.org/article/605280e763be432dbf575c5f3d970262
Autor:
Ângela Alice Amadeu Megale, Fábio Carlos Magnoli, Alexandre Kazuo Kuniyoshi, Leo Kei Iwai, Denise V. Tambourgi, Fernanda C. V. Portaro, Wilmar Dias da Silva
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 24, Iss 1, Pp 1-11 (2018)
Abstract Background Bitis arietans is a venomous snake found in sub-Saharan Africa and in parts of Morocco and Saudi Arabia. The envenomation is characterized by local and systemic reactions including pain, blistering, edema and tissue damage, beside
Externí odkaz:
https://doaj.org/article/7c560881156748fda6edad6cf8d79181
Autor:
Roberto Tadashi Kodama, Alexandre Kazuo Kuniyoshi, Cristiane Castilho Fernandes da Silva, Daniela Cajado-Carvalho, Bruno Duzzi, Douglas Ceolin Mariano, Daniel C. Pimenta, Rafael Borges, Wilmar Dias da Silva, Fernanda Calheta Vieira Portaro
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 26 (2020)
Abstract Background: Proteases play an important role for the proper physiological functions of the most diverse organisms. When unregulated, they are associated with several pathologies. Therefore, proteases have become potential therapeutic targets
Externí odkaz:
https://doaj.org/article/e855e045556240998a15b01bc1d05636
Autor:
David Gitirana da Rocha, Jorge Hernandez Fernandez, Claudia Maria Costa de Almeida, Claudia Letícia da Silva, Fabio Carlos Magnoli, Osmair Élder da Silva, Wilmar Dias da Silva
Publikováno v:
Data in Brief, Vol 13, Iss , Pp 717-722 (2017)
The data presented in this article are related to the research article entitled ''Development of IgY antibodies against anti-snake toxins endowed with highly lethal neutralizing activity'' (da Rocha et al., 2017) [1]. Complementarity-determining regi
Externí odkaz:
https://doaj.org/article/7cb82092a4454aeda0d1374a5db7f05a
Publikováno v:
Toxins, Vol 12, Iss 9, p 594 (2020)
Bitis arietans is a snake of medical importance, as it is responsible for more accidents in humans and domestic animals than all other African snakes put together. The accidents are characterized by local and systemic alterations, such as inflammatio
Externí odkaz:
https://doaj.org/article/e3a79336e7474dc0b37852ca90b1f9bc