Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Wilma Helena de Oliveira"'
Autor:
Wilma Helena de Oliveira, MariaEduarda Rocha França, Deniele Bezerra Lós, Clarissa Figueiredo Braga, Christina Alves Peixoto, Gabriel Barros Rodrigues, Eduardo Duarte-Silva, Sura Wanessa Santos Rocha, Shyrlene Meiry da Rocha Araújo
Publikováno v:
Experimental Brain Research. 239:2821-2839
Insulin deficiency or resistance can promote dementia and hallmarks of Alzheimer's disease (AD). The formation of neurofibrillary tangles of p-TAU protein, extracellular Aβ plaques, and neuronal loss is related to the switching off insulin signaling
Autor:
Gabriel Barros Rodrigues, Wilma Helena de Oliveira, Laise Aline Martins dos Santos, Francisco Jaime Bezerra Mendonça Junior, Maria Eduarda Rocha de França, Elquio Eleamen Oliveira, Deniele Bezerra Lós, Christina Alves Peixoto, Brennda Martins Gabínio
Publikováno v:
International Immunopharmacology. 64:280-288
The aim of the present study was to assess if the uninterrupted and prolonged administration of nanoparticles containing diethylcarbamazine (NANO-DEC) would cause liver, kidney and heart toxicity and then analyze for the first time its action in mode
Autor:
Ingrid Prata, Mendonça, Igor Henrique Rodrigues de, Paiva, Eduardo Pereira, Duarte-Silva, Michel Gomes de, Melo, Rodrigo Soares da, Silva, Wilma Helena de, Oliveira, Belmira Lara da Silveira Andrade da, Costa, Christina Alves, Peixoto
Publikováno v:
International Immunopharmacology. 102:108415
Thereabout 30-40% of patients with Parkinson's Disease (PD) also have depression contributing to the loss of quality of life. Among the patients who treat depression, about 50% do not show significant improvement due to the limited efficacy of the tr
Autor:
Wilma Helena de Oliveira, Fábia Cristiane Melo Leite de Lira, Elquio Eleamen Oliveira, Laise Aline Martins dos Santos, Francisco Jaime Bezerra Mendonça Junior, Maria Eduarda Rocha de França, Gabriel Barros Rodrigues, Christina Alves Peixoto, Deniele Bezerra Lós, Brennda Martins Gabínio
Publikováno v:
International Immunopharmacology. 50:330-337
Previous studies from our laboratory have demonstrated that Diethylcarbamazine (DEC) is a potent anti-inflammatory drug. The aim of the present study was to characterize the nanoencapsulation of DEC and to evaluate its effectiveness in a model of inf
Autor:
Karla Patrícia Sousa Barbosa, Christina Alves Peixoto, Wilma Helena de Oliveira, Ana Karolina Santana Nunes, Sura Wanessa Santos Rocha, Anne Gabrielle Vasconcelos de Oliveira, Laise Aline Martins dos Santos, Maria Eduarda Rocha de França, Gabriel Barros Rodrigues, Deniele Bezerra Lós
Publikováno v:
Inflammopharmacology. 26:599-609
While diethylcarbamazine citrate (DEC) displays important anti-inflammatory effects in experimental models of liver injury, the mechanisms of its action remain poorly understood. The aim of the present study was to investigate the fibrolytic potentia
Autor:
Rayana Leal Luna, Maria Eduarda Rocha de França, Wilma Helena de Oliveira, Christina Alves Peixoto, Chandrakant Tayade, Kasra Khalaj
Publikováno v:
Oncotarget
// Kasra Khalaj 1,2,* , Rayana Leal Luna 2,* , Maria Eduarda Rocha de Franca 2 , Wilma Helena de Oliveira 2 , Christina Alves Peixoto 2 and Chandrakant Tayade 1 1 Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, ON, Ca
Autor:
Wilma Helena de Oliveira, Liana Verinaud, Rodolfo Thomé, Christina Alves Peixoto, Fernanda Tovar-Moll, Ana Karolina Santana Nunes, Catarina Rapôso
Publikováno v:
Experimental Neurology. 275:143-153
While it has recently been shown that sildenafil (Viagra®) has a protective effect on myelination/remyelination, the mechanism of this protection is still unknown. In general, cytokines, chemokines and metalloproteinases have a pro-inflammatory acti
Autor:
Ana Karolina Santana Nunes, Karla Patrícia Sousa Barbosa, Rayana Leal Luna, Wilma Helena de Oliveira, Anne Gabrielle Vasconcelos, Christina Alves Peixoto
Publikováno v:
Cells Tissues Organs. 201:193-202
Lipopolysaccharide (LPS) injections during pregnancy are well established as models for pregnancy complications, including fetal growth restriction (FGR), thrombophilia, preterm labor and abortion. Indeed, inflammation, as induced by LPS injection ha
Autor:
Liana Verinaud, Crislayne Gonçalo de Santana Marinho, Gabriela Peron, Maria Eduarda Rocha de França, Wilma Helena de Oliveira, Amanda Pires Bonfanti, Livia Tomaz, Deniele Bezerra Lós, Eduardo Duarte-Silva, Shyrlene Meiry da Rocha Araújo, Christina Alves Peixoto
Publikováno v:
International Immunopharmacology. 85:106581
Multiple sclerosis (MS) is a chronic immuno-inflammatory disease of the central nervous system characterized by demyelination and axonal damage. Cognitive changes are common in individuals with MS since inflammatory molecules secreted by microglia in
Autor:
Liana Verinaud, Wilma Helena de Oliveira, Eduardo Duarte-Silva, Deniele Bezerra Lós, Gabriela Peron, Livia de Lima Thomaz, Christina Alves Peixoto, Maria Eduarda Rocha de França, Ana Karolina Santana Nunes, Shyrlene Meiry da Rocha Araújo, Amanda Pires Bonfanti
Publikováno v:
Journal of neuroimmunology. 321
Apoptosis is one form of cell death that is intimately related to health and pathological conditions. In most neuroinflammatory and/or neurodegenerative diseases, apoptosis is associated with disease development and pathology and inhibition of this p