Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Willy Morelle"'
Autor:
Zoé Durin, Marine Houdou, Willy Morelle, Lydia Barré, Aurore Layotte, Dominique Legrand, Mohamed Ouzzine, François Foulquier
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Glycosylation is a ubiquitous and universal cellular process in all domains of life. In eukaryotes, many glycosylation pathways occur simultaneously onto proteins and lipids for generating a complex diversity of glycan structures. In humans, severe g
Externí odkaz:
https://doaj.org/article/eac89051963b4e6c9bec41f0bc6d1671
Autor:
Tomasz M. Witkos, Wing Lee Chan, Merja Joensuu, Manuel Rhiel, Ed Pallister, Jane Thomas-Oates, A. Paul Mould, Alex A. Mironov, Christophe Biot, Yann Guerardel, Willy Morelle, Daniel Ungar, Felix T. Wieland, Eija Jokitalo, May Tassabehji, Uwe Kornak, Martin Lowe
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
COPI is recruited to the membrane by binding to Arf GTPases. Here the authors find that GORAB, a trans-Golgi protein, promotes COPI recruitment by forming membrane domains that also contain the COPI-interacting protein Scyl1, which is required for ef
Externí odkaz:
https://doaj.org/article/dc9f0e13809c4552a229477915667865
Autor:
Philippe A. Grange, Joël Raingeaud, Willy Morelle, Anne-Geneviève Marcelin, Vincent Calvez, Nicolas Dupin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Propionibacterium acnes (P. acnes) is a major skin-associated bacterium that was long considered commensal, until several studies revealed it to be an opportunistic pathogen. We investigated the ability of P. acnes surface proteins to recogn
Externí odkaz:
https://doaj.org/article/2189ef298cce4d45be1d65b8f3f15520
Autor:
Cyprien Jaillet, Willy Morelle, Marie-Christine Slomianny, Vincent Paget, Georges Tarlet, Valérie Buard, Sonia Selbonne, Fanny Caffin, Emilie Rannou, Pierre Martinez, Agnès François, François Foulquier, Fabrice Allain, Fabien Milliat, Olivier Guipaud
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract As it is altered by ionizing radiation, the vascular network is considered as a prime target in limiting normal tissue damage and improving tumor control in radiation therapy. Irradiation activates endothelial cells which then participate in
Externí odkaz:
https://doaj.org/article/f9690215a646472da6218ce07771cc2c
Autor:
Norbert Bakalara, Hugues Duffau, Jean-Luc Pirat, David Virieux, Jean-Noël Volle, Marc Lecouvey, Ludovic Clarion, Séverine Loiseau, Marcel Delaforge, Philippe Legrand, Emmanuelle Uro-Coste, Jean-Philippe Hugnot, Jacques Vignon, Willy Morelle, Salim Khiati, Soumaya Turpault, Ali Saleh, Zahra Hassani
Time lapse showing cell aggregation during neurosphere formation in control condition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8986be0313738a0c16855caa41a41ae
https://doi.org/10.1158/1541-7786.22512019
https://doi.org/10.1158/1541-7786.22512019
Autor:
Norbert Bakalara, Hugues Duffau, Jean-Luc Pirat, David Virieux, Jean-Noël Volle, Marc Lecouvey, Ludovic Clarion, Séverine Loiseau, Marcel Delaforge, Philippe Legrand, Emmanuelle Uro-Coste, Jean-Philippe Hugnot, Jacques Vignon, Willy Morelle, Salim Khiati, Soumaya Turpault, Ali Saleh, Zahra Hassani
Supplementary figures providing additionnal information concerning: - The cells glycome before and after PST3.1a treatment as measured by mass spectrometry (Supp. Figure 1) or Glycoprofile (Supp. Figure 2) - The absence of effect of PST3.1a on O-Glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57635f478bd6ab47186f5615d1ef3380
https://doi.org/10.1158/1541-7786.22512016
https://doi.org/10.1158/1541-7786.22512016
Autor:
Norbert Bakalara, Hugues Duffau, Jean-Luc Pirat, David Virieux, Jean-Noël Volle, Marc Lecouvey, Ludovic Clarion, Séverine Loiseau, Marcel Delaforge, Philippe Legrand, Emmanuelle Uro-Coste, Jean-Philippe Hugnot, Jacques Vignon, Willy Morelle, Salim Khiati, Soumaya Turpault, Ali Saleh, Zahra Hassani
Time lapse showing cell aggregation during neurosphere formation in PST3.1a-treated condition. In this condition, less cell aggregation is visible as compared to the control condition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43366e1b39e9e00e47b3ca99399d1624
https://doi.org/10.1158/1541-7786.22512022
https://doi.org/10.1158/1541-7786.22512022
Autor:
Norbert Bakalara, Hugues Duffau, Jean-Luc Pirat, David Virieux, Jean-Noël Volle, Marc Lecouvey, Ludovic Clarion, Séverine Loiseau, Marcel Delaforge, Philippe Legrand, Emmanuelle Uro-Coste, Jean-Philippe Hugnot, Jacques Vignon, Willy Morelle, Salim Khiati, Soumaya Turpault, Ali Saleh, Zahra Hassani
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor and accounts for a significant proportion of all primary brain tumors. Median survival after treatment is around 15 months. Remodeling of N-glycans by the N-acetylglucosam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::153d0c72de8a7328d1fbadd4b4997667
https://doi.org/10.1158/1541-7786.c.6540103.v1
https://doi.org/10.1158/1541-7786.c.6540103.v1
Autor:
Charlot De Wachter, Katelijne Geysens, Paul Ameloot, Nico Callewaert, Bart Samyn, Roland Contreras, José Martins, Pieter P. Jacobs, Jurgen Haustraete, Jean-Christophe Renauld, Simon Devos, Bram Laukens, Willy Morelle
Publikováno v:
Biotechnology and bioengineering
Biotechnology and bioengineering, 2020, Biotechnology and bioengineering, 117 (8), pp.2479-2488. ⟨10.1002/bit.27375⟩
Biotechnology and bioengineering, 2020, Biotechnology and bioengineering, 117 (8), pp.2479-2488. ⟨10.1002/bit.27375⟩
BackgroundThe glycosylation pathways of several eukaryotic protein expression hosts are being engineered to enable the production of therapeutic glycoproteins with humanized application-customized glycan structures. In several expression hosts, this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b98af807cd471ca24cf4ebc4de82e33
https://doi.org/10.1101/2020.01.28.923631
https://doi.org/10.1101/2020.01.28.923631
Autor:
Eudoxie Dulary, Thorsten Marquardt, Willy Morelle, Marie-Ange Krzewinski-Recchi, Marine Houdou, Romain Péanne, Corentin Spriet, Dorothée Vicogne, André Klein, François Foulquier, Geoffroy de Bettignies, Vladimir Lupashin, Sven Potelle, Sandrine Duvet, Leslie K. Climer, Gert Matthijs, Pierre Morsomme, Elodie Lebredonchel
Publikováno v:
Biochemical Journal
Biochemical Journal, 2017, 474 (9), pp.1481-1493. ⟨10.1042/BCJ20160910⟩
Biochemical Journal, 2017, 474 (9), pp.1481-1493. ⟨10.1042/BCJ20160910⟩
International audience; TMEM165 deficiencies lead to one of the congenital disorders of glycosylation (CDG), a group of inherited diseases where the glycosylation process is altered. We recently demonstrated that the Golgi glycosylation defect due to