Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Willy J Peumans"'
Autor:
Guillaume Poiroux, Marguerite Pitié, Raphaël Culerrier, Elodie Lafont, Bruno Ségui, Els J M Van Damme, Willy J Peumans, Jean Bernadou, Thierry Levade, Pierre Rougé, Annick Barre, Hervé Benoist
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23315 (2011)
Photochemotherapy is used both for solid tumors and in extracorporeal treatment of various hematologic disorders. Nevertheless, its development in oncology remains limited, because of the low selectivity of photosensitizers (PS) towards human tumor c
Externí odkaz:
https://doaj.org/article/a8620ab1c7fd4b5fb175c50679e15cb8
Autor:
Colin D. Reynolds, Lisa M. Wright, Pierre J. Rizkallah, Anthony K. Allen, Willy J. Peumans, Els Van Damme, Michael J. Donovan
Publikováno v:
Protein & Peptide Letters. 6:253-258
Abstract: In the last decade a number of single-domain mannose-binding lectins (11-14 kDa) have l:ieen characterised from different monocot plants and shown to belong to a superfamily of evolutionary related proteins. We have isolated and crystallize
Autor:
Jan M.C. Geuns, Johan Vanneste, Bart Van der Bruggen, Willy J. Peumans, Els J.M. Van Damme, Siavash Darvishmanesh, Kristel Bernaerts
Publikováno v:
Journal of Chemical Technology & Biotechnology. 89:354-371
The integration of natural or biomimetic ligands in membrane processes was explored, focusing on simplicity and originality, with an eye to increasing the often moderate selectivity. Due to their simple structure, selection and manufacturing procedur
Publikováno v:
Plant Physiology and Biochemistry. 49:46-54
The structural domain corresponding to the Galanthus nivalis agglutinin (GNA) is a mannose-binding motif that was originally discovered in plants but according to recent data also occurs in other eukaryotes and prokaryotes. Transcriptome analyses rev
Autor:
Thierry Levade, Hervé Benoist, Bruno Ségui, Raphaël Culerrier, Marguerite Pitié, Pierre Rougé, Guillaume Poiroux, Willy J. Peumans, Els J.M. Van Damme, Jean Bernadou, Annick Barre
Publikováno v:
Photochemistry and Photobiology. 87:370-377
Porphyrins are used as photosensitizer (PS) in photodynamic therapy in cancer treatment. Nevertheless, the development of photochemotherapy in oncology remains limited, because of the low selectivity of PSs. In order to allow PS targeting toward tumo
Autor:
Josef Makovitzky, Ufuk Gündüz, Meltem Demirel Kars, Willy J. Peumans, Joseph Molnár, Helga Engi, Nóra Gyémánt, Els J.M. Van Damme, Udo Schumacher, Péter Molnár
Publikováno v:
Scopus-Elsevier
Phospho-glycoprotein (P-gp) is a polytopic plasma membrane protein whose overexpression causes multidrug resistance (MDR) responsible for the failure of cancer chemotherapy. P-gp 170 is a member of the ATP-binding cassette (ABC) transporter superfami
Publikováno v:
Biochemical Society Transactions. 36:843-847
Protein turnover is a key post-translational event that regulates numerous cellular processes. It enables cells to respond rapidly to intracellular signals and changing environmental conditions by adjusting the levels of pivotal proteins. A major pro
Autor:
Rex A. Palmer, Laurent Maveyraud, Valérie Guillet, Colin D. Reynolds, Peter V. Konarev, Els J.M. Van Damme, Lionel Mourey, Dmitri I. Svergun, Willy J. Peumans, Pierre Rougé, Hideaki Niwa
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 75:89-103
Bark of elderberry (Sambucus nigra) contains a galactose (Gal)/N-acetylgalactosamine (GalNAc)-specific lectin (SNA-II) corresponding to slightly truncated B-chains of a genuine Type-II ribosome-inactivating protein (Type-II RIPs, SNA-V), found in the
Autor:
Paul Proost, Els Van Damme, David F. Smith, Savvas N. Savvides, Willy J. Peumans, Elke Fouquaert
Publikováno v:
Plant Physiology. 147:1316-1324
Molecular cloning of the “old” but still unclassified Euonymus europaeus agglutinin (EEA) demonstrated that the lectin is a homodimeric protein composed of 152 residue subunits. Analysis of the deduced sequence indicated that EEA is synthesized w
Autor:
Noboru Uchiyama, Sachiko Nakamura-Tsuruta, Kiichiro Totani, Els J.M. Van Damme, Willy J. Peumans, Jun Hirabayashi, Yukishige Ito
Publikováno v:
FEBS Journal. 275:1227-1239
The Jacalin-related lectin (JRL) family comprises galactose-binding-type (gJRLs) and mannose-binding-type (mJRLs) lectins. Although the documented occurrence of gJRLs is confined to the family Moraceae, mJRLs are widespread in the plant kingdom. A de