Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Willy Hofstetter"'
Autor:
Franziska Strunz, Saskia Gentil-Perret, Mark Siegrist, Marc Bohner, Nikola Saulacic, Willy Hofstetter
Publikováno v:
Bone Reports, Vol 20, Iss , Pp 101739- (2024)
Bisphosphonates (BP) are anti-resorptive drugs that are widely used to prevent bone loss in osteoporosis. Since inhibition of bone resorption will cause a decrease in bone formation through a process called coupling, it is hypothesized that extended
Externí odkaz:
https://doaj.org/article/c66ff10a93414038a7bd4b997a449417
Autor:
Sophia N. Verouti, Jonai Pujol-Giménez, Paola Bermudez-Lekerika, Laeticia Scherler, Rajesh Bhardwaj, Aurélien Thomas, Sébastien Lenglet, Mark Siegrist, Willy Hofstetter, Daniel G. Fuster, Matthias A. Hediger, Geneviève Escher, Bruno Vogt
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The metal ion transporter ZIP8 (SLC39A8) mediates cellular uptake of vital divalent metal ions. Genome-wide association studies (GWAS) showed that the single-nucleotide polymorphism (SNP) variant A391T (rs13107325) is associated with numerous human t
Externí odkaz:
https://doaj.org/article/4dd0962652ae49ec91bde16de4444a7d
Autor:
Rahel D. May, Daniela A. Frauchiger, Christoph E. Albers, Willy Hofstetter, Benjamin Gantenbein
Publikováno v:
Neurospine, Vol 17, Iss 1, Pp 77-87 (2020)
Objective Spinal fusion surgery is a common treatment modality for various pathologic conditions of the spine. The bone morphogenetic protein 2 (BMP2) analogue L51P acts as a general inhibitor of BMP antagonists, whereas it shows a weak affinity for
Externí odkaz:
https://doaj.org/article/4b73368d5f5244b0a4803376394d5265
Autor:
Weitian Zhao, David Michalik, Stephen Ferguson, Willy Hofstetter, Jacques Lemaître, Brigitte von Rechenberg, Paul Bowen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
In vitro testing of implant materials bioactivity is important and the current methods take time. Here, the authors report on the development of a faster titration based method for assessing the mineralization activity of materials and validate the m
Externí odkaz:
https://doaj.org/article/9a5e4180420c4a059f2518eb677453be
Autor:
Fatemeh Safari, Jeremy Yeoh, Margaux Bringardner, Mark Siegrist, Silvia Dolder, Franziska Strunz, Willy Hofstetter, Philippe Krebs
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 100795- (2021)
Externí odkaz:
https://doaj.org/article/9bafac05097747059ed044e4e021e62d
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 100834- (2021)
Externí odkaz:
https://doaj.org/article/6dc37c23084547129b6ad2252c864b1b
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100460- (2020)
Externí odkaz:
https://doaj.org/article/d8d2b3d244664996aad495eca7d423ec
Autor:
Michel Hauser, Mark Siegrist, Alain Denzer, Nikola Saulacic, Joël Grosjean, Marc Bohner, Willy Hofstetter
Publikováno v:
Journal of Orthopaedic Surgery, Vol 26 (2018)
Treatment of osteoporotic patients with bisphosphonates (BPs) preserves bone mass and microarchitecture. The high prescription rate of the drugs brings about increases in the numbers of fractures and bone defects requiring surgical interventions in t
Externí odkaz:
https://doaj.org/article/2074dc375d1142bfb170314ae76e3c37
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120857 (2015)
Cartilage is a tissue with limited self-healing potential. Hence, cartilage defects require surgical attention to prevent or postpone the development of osteoarthritis. For cell-based cartilage repair strategies, in particular autologous chondrocyte
Externí odkaz:
https://doaj.org/article/7ba9fa91dc4249219430d530fd80ce87
Autor:
Giuseppe Albano, Matthias Moor, Silvia Dolder, Mark Siegrist, Carsten A Wagner, Jürg Biber, Nati Hernando, Willy Hofstetter, Olivier Bonny, Daniel G Fuster
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125104 (2015)
Osteoclasts are multinucleated bone degrading cells. Phosphate is an important constituent of mineralized bone and released in significant quantities during bone resorption. Molecular contributors to phosphate transport during the resorptive activity
Externí odkaz:
https://doaj.org/article/959f2d6820b740aea094799b94fa01a1