Výsledky vyhledávání - "Willy Berlier"

Akademický článek

A Recombinant Raccoon Poxvirus Vaccine Expressing both Yersinia pestis F1 and Truncated V Antigens Protects Animals against Lethal Plague

Autor: Tonie E. Rocke, Brock Kingstad-Bakke, Willy Berlier, Jorge E. Osorio

Publikováno v: Vaccines, Vol 2, Iss 4, Pp 772-784 (2014)

In previous studies, we demonstrated in mice and prairie dogs that simultaneous administration of two recombinant raccoon poxviruses (rRCN) expressing Yersinia pestis antigens (F1 and V307—a truncated version of the V protein) provided superior pro

Externí odkaz: https://doaj.org/article/73c5864892a04859ac9da03db1846f31

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Innovative approach in Pompe disease therapy: Induction of immune tolerance by antigen-encapsulated red blood cells

Autor: Willy Berlier, Quitterie Barthe, Gaelle Campello, Yann Godfrin, Nathalie Guerin, Françoise Horand, Magali Cremel

Publikováno v: International Journal of Pharmaceutics. 491:69-77

Pompe disease is a glycogen storage disease caused by acid α-glucosidase enzyme deficiency. Currently, the unique treatment is lifelong enzyme replacement therapy ERT with frequent intravenous administration of the recombinant analog alglucosidase-�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc25f8459b43ddbce5924691a0123d38
https://doi.org/10.1016/j.ijpharm.2015.05.062

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Methionine tumor starvation by erythrocyte-encapsulated methionine gamma-lyase activity controlled with per os vitamin B6

Autor: Yann Godfrin, Vanessa Bourgeaux, Angie Tainturier, Delphine Maucort-Boulch, Françoise Horand, Karine Senechal, Karine Aguera, Jérôme Honnorat, Willy Berlier

Publikováno v: Cancer Medicine
Cancer Medicine, 2017, 6, pp.1437-1452. ⟨10.1002/cam4.1086⟩
Cancer Medicine, Wiley, 2017, 6, pp.1437-1452. ⟨10.1002/cam4.1086⟩

Erymet is a new therapy resulting from the encapsulation of a methionine gamma‐lyase (MGL; EC number 4.4.1.11) in red blood cells (RBC). The aim of this study was to evaluate erymet potential efficacy in methionine (Met)‐dependent cancers. We pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d3993505de2654f68d5ea924e1a7e9
https://hal.science/hal-02049678

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A Recombinant Raccoon Poxvirus Vaccine Expressing both Yersinia pestis F1 and Truncated V Antigens Protects Animals against Lethal Plague

Autor: Willy Berlier, Tonie E. Rocke, Jorge E. Osorio, Brock Kingstad-Bakke

Publikováno v: Vaccines, Vol 2, Iss 4, Pp 772-784 (2014)
Vaccines
Volume 2
Issue 4
Pages 772-784

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b925607d820edf841a3fbfbb345de473
http://www.mdpi.com/2076-393X/2/4/772

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Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma

Autor: Jean-Baptiste Bachet, Fabien Gay, Raphaël Maréchal, Marie-Pierre Galais, Antoine Adenis, David Salako, MsC, Jerome Cros, Pieter Demetter, Magali Svrcek, Armelle Bardier-Dupas, Jean-François Emile, Pascal Hammel, Christelle Ebenezer, Willy Berlier, Yann Godfrin, Thierry André

Publikováno v: Pancreas. 44(7)

Asparaginase encapsulated in erythrocytes (ERY-ASP) is a potentially effective drug in patients with pancreatic adenocarcinoma (PAC) with null/low asparagine synthetase (ASNS) expression. Our aims were to assess ASNS expression in PAC from a large co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2daac6f62916e124cc469fddf892534
https://pubmed.ncbi.nlm.nih.gov/26355551

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Abstract 2356: Erythrocytes used as tumor antigen delivery system to target antigen-presenting cells embody an innovative approach for in situ cancer immunotherapy

Autor: Willy Berlier, Yann Godfrin, Françoise Horand, Nathalie Guerin, Magali Cremel, Vanessa Bourgeaux, Quitterie Barthe

Publikováno v: Cancer Research. 76:2356-2356

Introduction: In current vaccine therapy, efficient delivery of tumor antigens (TA) to antigen-presenting cells (APC) represents a major step toward the development of strong TA-specific immune response including cytotoxic T lymphocyte (CTL) inductio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e5a18a94bd2c9efd23c2713db9dae72
https://doi.org/10.1158/1538-7445.am2016-2356

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Abstract 4812: Arginine deiminase loaded in erythrocytes: a promising formulation for L-arginine deprivation therapy in cancers

Autor: Fabien Gay, Karine Aguera, Karine Senechal, Julie Bes, Anne-Marie Chevrier, Fanny Gallix, Christine Guicher, Philip Lorenzi, Vanessa Bourgeaux, Willy Berlier, Françoise Horand, Yann Godfrin

Publikováno v: Cancer Research. 76:4812-4812

Based on the asparaginase paradigm, several arginine-catabolizing enzymes have been developed for the treatment of arginine-dependent cancers (Wheatley, 2004). The arginine deiminase (ADI) enzyme catalyzes the hydrolysis of arginine (Arg) (Sugimura,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6cda06b3599f52d124070e3a29c7b89
https://doi.org/10.1158/1538-7445.am2016-4812

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Detection of enterovirus in human skeletal muscle from patients with chronic inflammatory muscle disease or fibromyalgia and healthy subjects

Autor: Shabir Omar, Rafik Harrath, Léonard Féasson, Thomas Bourlet, Florence Grattard, Fatima Douche-Aourik, Willy Berlier, Christian Denis, Bruno Pozzetto

Publikováno v: Journal of Medical Virology. 71:540-547

Enterovirus RNA has been found previously in specimens of muscle biopsy from patients with idiopathic dilated cardiomyopathy, chronic inflammatory muscle diseases, and fibromyalgia or chronic fatigue syndrome (fibromyalgia/chronic fatigue syndrome).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70e99757e3d101e3b8d432f22beecac9
https://doi.org/10.1002/jmv.10531

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Abstract 5369: Low asparagine synthetase expression and in vitro sensitivity highlights L-asparaginase potential for the treatment of aggressive lymphomas

Autor: Karine Aguera, Anne-Marie Chevrier, Alexandra Traverse-Glehen, Yann Godfrin, Willy Berlier, Fanny Gallix

Publikováno v: Cancer Research. 75:5369-5369

L-asparaginase (L-ASPA) is included in current chemotherapy regimen for the treatment of acute lymphoblastic leukemia (ALL). The sensitivity of ALL to L-ASPA has been linked to the incapacity of leukemic cells to produce their own asparagine, since t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8eb7c6c474b7b0c1da62c6715e5b4137
https://doi.org/10.1158/1538-7445.am2015-5369

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