Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Wills, Ken N."'
Autor:
Wendy Hancock, Wills Ken N, Doug Cornell, Suganto Sutjipto, Jenny Avanzini, Murali Ramachandra, Chris Wilson, Peter Pelka, John A. Howe, Robert Ralston, Doug Antelman, Mark T. Horn
Publikováno v:
Virology. 345(1):220-230
Production of E1-deleted adenovirus (rAd) vectors requires complementation by E1A and E1B functions provided by the production cell line. The two cell lines most commonly used for production of rAd vectors, 293 and Per.C6, were derived from human pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb58651a23d5b362e58d2f4e55dbcf4
Autor:
Barry J. Sugarman, John A. Howe, Machemer T, Nodelman M, Daniel C. Maneval, Demers Gw, Shu Fen Wen, Nagabhushan Tl, Wills Ken N, Duane E. Johnson, Heidrun Engler, Shinoda J, Beltran J, Iqbal Ahmed Cm
Publikováno v:
Cancer Gene Therapy. 8:788-795
A recombinant adenovirus expressing human interferon alpha2b driven by the cytomegalovirus promoter, IACB, was shown to produce and secrete biologically active protein in vitro and in vivo. Intravenous administration of IACB in Buffalo rats resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9357dd595e3e4ab81a6503c0e23ab84
https://doi.org/10.1038/sj.cgt.7700364
https://doi.org/10.1038/sj.cgt.7700364
Autor:
Jenny Avanzini, Shu Fen Wen, Mei Vaillancourt, Isabella A. Atencio, Duane E. Johnson, Robert O. Ralston, Wills Ken N, Saskia Neuteboom, Jennifer Philopena, Suganto Sutjipto, Anne Phelan
Publikováno v:
Journal of Virology. 75:8733-8741
In vitro experiments have demonstrated intercellular trafficking of the VP22 tegument protein of herpes simplex virus type 1 from infected cells to neighboring cells, which internalize VP22 and transport it to the nucleus. VP22 also can mediate inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14267232dbda919cb2ba3ebacf7e462d
https://doi.org/10.1128/jvi.75.18.8733-8741.2001
https://doi.org/10.1128/jvi.75.18.8733-8741.2001
Autor:
T.L. Nagabhushan, Duane E. Johnson, Barry J. Sugarman, Wills Ken N, Robert Bookstein, Chulbul M. I. Ahmed, Diganta Saha
Publikováno v:
Human Gene Therapy. 10:77-84
A replication-deficient adenovirus encoding human interferon alpha2b, driven by the human cytomegalovirus (CMV) promoter, was constructed and characterized. This construct was used to infect human cells derived from different types of cancer. The pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5251c0ba3fa83e84288bae3cd411dea8
https://doi.org/10.1089/10430349950019200
https://doi.org/10.1089/10430349950019200
Autor:
Scott C. Anderson, H Köck, Daniel C. Maneval, H M Shepard, Machemer T, W Hancock, M Westphal, Suganto Sutjipto, Richard J. Gregory, Matthew P. Harris, Wills Ken N
Publikováno v:
International Journal of Cancer. 67:808-815
Alterations in the p53 tumor-suppressor gene occur in 35-60% of human glioblastomas, and re-introduction of p53 can suppress neoplastic growth. To evaluate the potential for p53 gene therapy of glioblastoma, we have analyzed the response of human gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b0c3be03abc42d35bae34cbde59c983
https://doi.org/10.1002/(sici)1097-0215(19960917)67:6<808::aid-ijc9>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19960917)67:6<808::aid-ijc9>3.0.co
Autor:
Jenny Avanzini, Wills Ken N, Gaby Terracina, Xiaomei Jin, Drake LaFace, Loretta L. Nielsen, Rob Bookstein, Van Tsai, Bin Shi
Publikováno v:
Cancer gene therapy. 8(12)
Progressive growth and metastasis of solid tumors require angiogenesis, or the formation of new blood vessels. Endostatin is a 20-kDa carboxy-terminal fragment of collagen XVIII that has been shown to inhibit endothelial cell proliferation and tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258b3c62dc27bea18d898feaac3c43fd
https://pubmed.ncbi.nlm.nih.gov/11781661
https://pubmed.ncbi.nlm.nih.gov/11781661
Autor:
Duane E. Johnson, T.L. Nagabhushan, Murali Ramachandra, Barry J. Sugarman, John A. Howe, C.M. Iqbal Ahmed, Wills Ken N
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 21(6)
Replication-deficient adenoviruses expressing human interferon-alpha2b (HuIFN-alpha2b) or the hybrid IFN-alpha2alpha1 or those with the secretory signal deleted, whose express is driven by the alpha-fetoprotein (AFP) promoter, were constructed and ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a79bc9c81e6c4c4381b83bd82e936a4
https://pubmed.ncbi.nlm.nih.gov/11440637
https://pubmed.ncbi.nlm.nih.gov/11440637
Autor:
Patricia Menzel, Mei-Ting Vaillancourt, Duane E. Johnson, Whei-Mei Huang, Shu Fen Wen, Scott C. Anderson, Robert Bookstein, H. Michael Shepard, Daniel C. Maneval, Richard J. Gregory, Matthew P. Harris, Suganto Sutjipto, Wills Ken N
Publikováno v:
Human gene therapy. 5(9)
We have constructed recombinant human adenoviruses that express wild-type human p53 under the control of either the Ad 2 major late promoter (MLP) or the human cytomegalovirus (CMV) immediate early gene promoter. Each construct replaces the Ad 5 E1a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e05f8a83e8cbc2ef0f23c72df33fbcf
https://pubmed.ncbi.nlm.nih.gov/7833367
https://pubmed.ncbi.nlm.nih.gov/7833367
Autor:
Iqbal Ahmed, C M, Johnson, Duane E, Demers, G William, Engler, Heidren, Howe, John A, Wills, Ken N, Wen, Shu-Fen, Shinoda, Jeremy, Beltran, Josie, Nodelman, Margarita, Machemer, Todd, Maneval, Dan C, Nagabhushan, Tatanahalli L, Sugarman, Barry J
Publikováno v:
Cancer Gene Therapy; Oct2001, Vol. 8 Issue 10, p788, 8p
Autor:
Köck, Helge, Harris, Matthew P., Anderson, Scott C., Machemer, Todd, Hancock, Wendy, Sutjipto, Suganto, Wills, Ken N., Gregory, Richard J., Shepard, H. Michael, Westphal, Manfred, Maneval, Daniel C.
Publikováno v:
International Journal of Cancer; Sep1996, Vol. 67 Issue 6, p808-815, 8p