Rational antibody design for undruggable targets using kinetically controlled biomolecular probes.

Autor: Trkulja CL; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden., Jungholm O; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Davidson M; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden., Jardemark K; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Marcus MM; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Hägglund J; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden.; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Karlsson A; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden.; Nanoxis Consulting AB, SE-40016 Gothenburg, Sweden., Karlsson R; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden.; Nanoxis Consulting AB, SE-40016 Gothenburg, Sweden., Bruton J; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Ivarsson N; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Srinivasa SP; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden., Cavallin A; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Svensson P; Integrative Research Laboratories, SE-41346, Gothenburg, Sweden., Jeffries GDM; Fluicell AB, SE-431 37 Mölndal, Sweden., Christakopoulou MN; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Reymer A; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden.; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-405 30 Gothenburg, Sweden., Ashok A; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden., Willman G; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden., Papadia D; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden., Johnsson E; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden., Orwar O; Oblique Therapeutics AB, SE-41346 Gothenburg, Sweden. owe.orwar@ki.se.; Department of Physiology and Pharmacology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

Publikováno v: Science advances [Sci Adv] 2021 Apr 16; Vol. 7 (16). Date of Electronic Publication: 2021 Apr 16 (Print Publication: 2021).

441P - OT-1096: A first-in-class immunoactivating small molecule that targets the thioredoxin reductase/thioredoxin axis causes strong tumor growth inhibition by downregulating intratumoral tregs in a humanized TNBC-PDX model

Autor: Orwar, O., Lowstedt, I., Andersson, K., Gannedahl, G., Willman, G., Davidsson, M., Stafford, W., Trkulja, C.

Publikováno v: In Annals of Oncology October 2018 29 Supplement 8

The global contribution of crystal boundaries and bio-physical characteristics in the understanding of cellular interaction of fibroblasts with the nanoscale surface.

Autor: Misra, R.D.K., Enchinton, A.

Publikováno v: Materials Technology; Dec2024, Vol. 39 Issue 1, p1-5, 5p

PILOT: measuring the FIR astrophysical dust emission

Autor: Bernard, Jean-Philippe, Ade, P., Andre, Y., Debernardis, P., Boulade, O., Bouzit, M., Brais, N., Caillat, A., Camus, T., Daddato, R., Dubois, J. P., Douchin, F., Doumayrou, E., Engel, C., Evrard, J., Gomes, A., Hargrave, P., Laureijs, R., Lepennec, Y., Leriche, B., Longval, Y., Maestre, S., Martignac, J., Marty, C., Marty, W., Masi, S., Mirc, F., Narbonne, J., Otrio, G., Pajot, F., Pimentao, J., Ponthieu, N., Rambaud, D., Ristorcelli, I., Rodriguez, L., Roudil, G., Salatino, M., Savini, G., Tauber, J., Torre, J. P., Carole Tucker, Versepuech, G., Willman, G.

Publikováno v: NASA Astrophysics Data System

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1e5ce44f19d50e2e205464427e6fc9bc
https://ui.adsabs.harvard.edu/#abs/2010cosp...38.4075B

Hypobaric hypoxia triggers pyroptosis in the retina via NLRP3 inflammasome activation.

Autor: Xin, Xiaorong, Yang, Kun, Liu, Haiping, Li, Yanrong

Publikováno v: Apoptosis; Apr2022, Vol. 27 Issue 3/4, p222-232, 11p