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Thiopurine 6TG treatment increases tumor immunogenicity and response to immune checkpoint blockade.

Autor: Nazerai L; Melanoma Research Team, Danish Cancer Society Research Center, Copenhagen, Denmark.; Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Willis SC; Melanoma Research Team, Danish Cancer Society Research Center, Copenhagen, Denmark.; Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Yankilevich P; Bioinformatics Core Facility, Instituto de Investigación En Biomedicina de Buenos Aires (Ibioba), Buenos Aires, Argentina., Di Leo L; Melanoma Research Team, Danish Cancer Society Research Center, Copenhagen, Denmark., Bosisio FM; Lab of Translational Cell and Tissue Research, University of Leuven, Leuven, Belgium., Frias A; Melanoma Research Team, Danish Cancer Society Research Center, Copenhagen, Denmark., Bertolotto C; Universite Côte d'Azur, Nice, France.; INSERM, Biology and Pathologies of melanocytes, team1, Equipe labellisée Ligue 2020, Centre Méditerranéen de Médecine Moléculaire, Nice, France., Nersting J; Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Thastrup M; Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Buus S; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Thomsen AR; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Nielsen M; Department of Health Technology, Section for Bioinformatics, Technical University of Denmark, Lyngby, Denmark., Rohrberg KS; Department of Oncology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Schmiegelow K; Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., De Zio D; Melanoma Research Team, Danish Cancer Society Research Center, Copenhagen, Denmark.; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.

Publikováno v: Oncoimmunology [Oncoimmunology] 2022 Dec 17; Vol. 12 (1), pp. 2158610. Date of Electronic Publication: 2022 Dec 17 (Print Publication: 2023).