Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Willine J. van de Wetering"'
Autor:
Tim C van Smaalen, Danielle M H Beurskens, Jasper J H F M Kox, Rasheendra Polonia, Rein Vos, Hans Duimel, Willine J van de Wetering, Carmen López-Iglesias, Chris P Reutelingsperger, L W Ernest van Heurn, Carine J Peutz-Kootstra, Gerry A F Nicolaes
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0279944 (2023)
Extracellular histones are cytotoxic molecules involved in experimental acute kidney injury. In patients receiving a renal transplant from donors after circulatory death, who suffer from additional warm ischemia, worse graft outcome is associated wit
Externí odkaz:
https://doaj.org/article/7fcf7b59f41e4937a8360811da496825
Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation
Autor:
Gui-Wei He, Lin Lin, Jeff DeMartino, Xuan Zheng, Nadzeya Staliarova, Talya Dayton, Harry Begthel, Willine J. van de Wetering, Eduard Bodewes, Jeroen van Zon, Sander Tans, Carmen Lopez-Iglesias, Peter J. Peters, Wei Wu, Daniel Kotlarz, Christoph Klein, Thanasis Margaritis, Frank Holstege, Hans Clevers
Publikováno v:
Cell stem cell, 29(9), 1333-1345.e6. Cell Press
Cell Stem Cell, 29(12), 1718-1720. Cell Press
Cell Stem Cell, 29(12), 1718-1720. Cell Press
Opposing roles have been proposed for IL-22 in intestinal pathophysiology. We have optimized human small intestinal organoid (hSIO) culturing, constitutively generating all differentiated cell types while maintaining an active stem cell compartment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6b3a4a7a07934d4cb43c7ee02e1304
https://doi.org/10.1016/j.stem.2022.11.001
https://doi.org/10.1016/j.stem.2022.11.001
Autor:
Jelte van der Vaart, Lynn Bosmans, Stijn F. Sijbesma, Kèvin Knoops, Willine J. van de Wetering, Henny G. Otten, Harry Begthel, Inne H. M. Borel Rinkes, Jeroen Korving, Eef G. W. M. Lentjes, Carmen Lopez-Iglesias, Peter J. Peters, Hanneke M. van Santen, Menno R. Vriens, Hans Clevers
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 118(51). National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 118(51):2117017118. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 118(51):2117017118. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Significance The thyroid is essential for maintaining systemic homeostasis by regulating thyroid hormone concentrations in the bloodstream. This study describes an organoid-based model system to study mouse and human thyroid biology. Moreover, the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29f9a142bae2301e2d713e6dacdc5eb
https://doi.org/10.1073/pnas.2117017118
https://doi.org/10.1073/pnas.2117017118
Autor:
Jeroen Korving, Lena Böttinger, Norman Sachs, Peter J. Peters, Willine J. van de Wetering, Jelte van der Vaart, Kèvin Knoops, Kerem Eitan, Harry Begthel, Carmen López-Iglesias, Alex Gileles-Hillel, Hans Clevers, Maarten H. Geurts
Publikováno v:
EMBO Reports
Embo Reports, 22(12):e52058. Wiley
EMBO Reports, 22(12). Nature Publishing Group
Embo Reports, 22(12):e52058. Wiley
EMBO Reports, 22(12). Nature Publishing Group
Patient‐derived human organoids can be used to model a variety of diseases. Recently, we described conditions for long‐term expansion of human airway organoids (AOs) directly from healthy individuals and patients. Here, we first optimize differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd7a3bb097fb776aa98279eded1a78f
https://cris.maastrichtuniversity.nl/en/publications/b9053ec6-b63a-412d-a892-5bb118aba269
https://cris.maastrichtuniversity.nl/en/publications/b9053ec6-b63a-412d-a892-5bb118aba269
Autor:
Sarah A. Teichmann, Peter J. Peters, Aurelia Saftien, Franka H van der Linden, Reinier van der Linden, Maarten H. Geurts, Alexander Ross, Cayetano Pleguezuelos-Manzano, Julia Bauzá-Martinez, Albert J. R. Heck, Hans Clevers, Hugo J. Snippert, Delilah F. G. Hendriks, Carmen López-Iglesias, Benedetta Artegiani, Georg A. Busslinger, Wei Wu, Rasa Elmentaite, Yotam E. Bar-Ephraim, Willine J. van de Wetering, Charelle Boot, Amanda Andersson-Rolf, Harry Begthel, Adriana Martinez-Silgado, Kai Kretzschmar, Bas Ponsioen, Kylie R. James, Joep Beumer, Joachim Goedhart, Jens Puschhof, Yorick Post, Matthias Zilbauer
Publikováno v:
Cell, 181(6), 1291-1306.e19. Elsevier B.V.
Cell, 181(6), 1291-+. Cell Press
Cell
Cell, 181(6), 1291-+. Cell Press
Cell
Enteroendocrine cells (EECs) sense intestinal content and release hormones to regulate gastrointestinal activity, systemic metabolism, and food intake. Little is known about the molecular make-up of human EEC subtypes and the regulated secretion of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb3dc1f58bdcd8d9787afa61b297e1c
https://pure.knaw.nl/portal/en/publications/73363b0c-8425-47f7-bb59-62156970642e
https://pure.knaw.nl/portal/en/publications/73363b0c-8425-47f7-bb59-62156970642e
Autor:
Miranda de Graaf, Hans Duimel, Joep Beumer, Peter J. Peters, Bart L. Haagmans, Willine J. van de Wetering, Tim I Breugem, Jelte van der Vaart, Elly van Donselaar, J. Paul van Schayck, Samra Riesebosch, Debby Schipper, Hans Clevers, Kèvin Knoops, Anna Z Mykytyn, Edwin Cuppen, Mart M. Lamers, Helma J.H. Kuijpers, Raimond B. G. Ravelli, Marion Koopmans, Jens Puschhof
Publikováno v:
Science
Science (New York, N.y.)
Science, 369(6499), 50-54. American Association for the Advancement of Science
Science, 369(6499), 50-54. American Association for the Advancement of Science (AAAS)
Science (New York, N.y.)
Science, 369(6499), 50-54. American Association for the Advancement of Science
Science, 369(6499), 50-54. American Association for the Advancement of Science (AAAS)
Intestinal organoids as an infection model Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes an influenza-like disease with a respiratory transmission route; however, patients often present with gastrointestinal symptoms such as dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8acdfeea3d0eafa02ce7a4ed2afe1ea5