Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Willianne I. M. Vonk"'
Autor:
Willianne I M Vonk, Vaishali Kakkar, Paulina Bartuzi, Dick Jaarsma, Ruud Berger, Marten H Hofker, Leo W J Klomp, Cisca Wijmenga, Harm H Kampinga, Bart van de Sluis
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e92408 (2014)
The Copper Metabolism MURR1 domain protein 1 (COMMD1) is a protein involved in multiple cellular pathways, including copper homeostasis, NF-κB and hypoxia signalling. Acting as a scaffold protein, COMMD1 mediates the levels, stability and proteolysi
Externí odkaz:
https://doaj.org/article/4cda9e3091094d0296a52e3bdaa2dc0b
Autor:
T. Kelly Rainbolt, Willianne I. M. Vonk, Ashley E. Webb, Judith Frydman, Anne Brunet, Patrick T. Dolan
Publikováno v:
Mol Cell
SummaryNeural stem and progenitor cells (NSPCs) are critical for continued cellular replacement in the adult brain. Life-long maintenance of a functional NSPC pool necessitates stringent mechanisms to preserve a pristine proteome. We find that the NS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f277a9043640e22a9bcbf1bbf06ec71
Autor:
Willianne I M Vonk, Paulina Bartuzi, Prim de Bie, Niels Kloosterhuis, Catharina G K Wichers, Ruud Berger, Susan Haywood, Leo W J Klomp, Cisca Wijmenga, Bart van de Sluis
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29183 (2011)
Canine copper toxicosis is an autosomal recessive disorder characterized by hepatic copper accumulation resulting in liver fibrosis and eventually cirrhosis. We have identified COMMD1 as the gene underlying copper toxicosis in Bedlington terriers. Al
Externí odkaz:
https://doaj.org/article/e50a1f85e64e48528a1bbc3cc33347cf
Autor:
Steffen J, Sahl, Willianne I M, Vonk
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1873
Fluorescence-based nanoscopy methods (also known as "superresolution" microscopy) have substantially expanded our options to examine the distributions of molecules inside cells with nanometer-scale resolution and molecular specificity. In the biophys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::952dc079bb5ef711a2b82090e0cbf597
https://pubmed.ncbi.nlm.nih.gov/30341614
https://pubmed.ncbi.nlm.nih.gov/30341614
Autor:
Willianne I. M. Vonk, Steffen J. Sahl
Publikováno v:
Methods in Molecular Biology ISBN: 9781493988198
Fluorescence-based nanoscopy methods (also known as "superresolution" microscopy) have substantially expanded our options to examine the distributions of molecules inside cells with nanometer-scale resolution and molecular specificity. In the biophys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91f4d98ab6abc2e0eeb560ac2b54a079
https://doi.org/10.1007/978-1-4939-8820-4_15
https://doi.org/10.1007/978-1-4939-8820-4_15
Autor:
Prim de Bie, Willianne I. M. Vonk, Cisca Wijmenga, Ruud Berger, Leo W. J. Klomp, Rozemarijn van der Plaats, Bart van de Sluis, Catharina G.K. Wichers, Peter V. E. van den Berghe
Publikováno v:
Cellular and molecular life sciences, 69(1), 149-163. SPRINGER BASEL AG
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences
Menkes disease (MD) is an X-linked recessive disorder characterized by copper deficiency resulting in a diminished function of copper-dependent enzymes. Most MD patients die in early childhood, although mild forms of MD have also been described. A di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f048c954ecb2c311198257ee7ea45d7
https://doi.org/10.1007/s00018-011-0743-1
https://doi.org/10.1007/s00018-011-0743-1
Publikováno v:
The Journal of Biological Chemistry, 285(37), 28991-29000. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
The maturation and activation of the anti-oxidant Cu, Zn superoxide dismutase (SOD1) are highly regulated processes that require several post-translational modifications. The maturation of SOD1 is initiated by incorporation of zinc and copper ions fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc7587370e397f58670b53bc0cc38cf
https://doi.org/10.1074/jbc.M110.101477
https://doi.org/10.1074/jbc.M110.101477
Autor:
Willianne I. M. Vonk, Leo W. J. Klomp
Publikováno v:
Biochemical Society Transactions. 36:1322-1328
ALS (amyotrophic lateral sclerosis) is a devastating progressive neurodegenerative disorder resulting in selective degeneration of motor neurons in brain and spinal cord and muscle atrophy. In approx. 2% of all cases, the disease is caused by a mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0fa0f4f3d091b41f79254c61cd9ecb
https://doi.org/10.1042/bst0361322
https://doi.org/10.1042/bst0361322
Autor:
Lana Lau, W. E. Moerner, Judith Frydman, Steffen J. Sahl, Lucien E. Weiss, Willianne I. M. Vonk
Publikováno v:
Quarterly reviews of biophysics
Aberrant aggregation of improperly folded proteins is the hallmark of several human neurodegenerative disorders, including Huntington's Disease (HD) with autosomal-dominant inheritance. In HD, expansion of the CAG-repeat-encoded polyglutamine (polyQ)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed40649fb08c8a3f774cd95032bdc22
https://pubmed.ncbi.nlm.nih.gov/26350150
https://pubmed.ncbi.nlm.nih.gov/26350150
Autor:
Lana Lau, W. E. Moerner, Judith Frydman, Steffen J. Sahl, Lucien E. Weiss, Willianne I. M. Vonk
Publikováno v:
Biophysical Journal. 106(2)
The identities of toxic aggregate species in Huntington's disease (HD) pathogenesis remain ambiguous. While polyQ-expanded mutant huntingtin (Htt) is known to accumulate in compact inclusion bodies inside neurons, this is widely thought to be a prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84defbe9048e4a204d867c9ffcc5e462