Výsledky vyhledávání - "Willian Robert Gomes"

Association between Polymorphisms of Hemochromatosis (HFE), Blood Lead (Pb) Levels, and DNA Oxidative Damage in Battery Workers

Autor: Willian Robert Gomes, Paula Pícoli Devóz, Bruno Alves Rocha, Denise Grotto, Juliana Mara Serpeloni, Bruno Lemos Batista, Alexandros G. Asimakopoulos, Kurunthachalam Kannan, Fernando Barbosa Jr., Gustavo Rafael Mazzaron Barcelos

Publikováno v: International Journal of Environmental Research and Public Health
Volume 20
Issue 4
Pages: 3513

Occupational exposure to lead (Pb) continues to be a serious public health concern and may pose an elevated risk of genetic oxidative damage. In Brazil, car battery manufacturing and recycling factories represent a great source of Pb contamination, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8629ba07d56066c2ad14e9c9a98d82
https://doi.org/10.3390/ijerph20043513

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Adaptive epigenetic response of glutathione (GSH)-related genes against lead (Pb)-induced toxicity, in individuals chronically exposed to the metal

Autor: Paula Pícoli Devóz, Flora Troina Maraslis, Lusânia Maria Greggi Antunes, Fernando Barbosa, Rui Manuel Reis, Gustavo Rafael Mazzaron Barcelos, Willian Robert Gomes, Mariana Bisarro dos Reis, Denise Grotto, Bruno Lemos Batista, Diego Luis Ribeiro

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

It is well known that one of the most outstanding adverse effects related to lead (Pb) exposure is oxidative stress; moreover, recent findings suggest that disturbances of the redox status of cells are associated with epigenetic responses, and metabo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e627472dcf25761929441cfe5c06fc89
https://pubmed.ncbi.nlm.nih.gov/33143897

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Polymorphisms of genes related to metabolism of lead (Pb) are associated with the metal body burden and with biomarkers of oxidative stress

Autor: Fernando Barbosa, Willian Robert Gomes, Bruno Limonti Cano Luiz, Paula Pícoli Devóz, Gustavo Rafael Mazzaron Barcelos, Bruno Lemos Batista, Denise Grotto

Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 836:42-46

Individual susceptibility to the toxic effects induced by exposure to lead (Pb) may be affected by several variables, such as environmental factors, as well as intrinsic variations among the individuals, which are hypothetically associated to genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84616307c4209eca7d1642eeb241bba
https://doi.org/10.1016/j.mrgentox.2018.05.016

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Milk and Dairy Products Intake Is Associated with Low Levels of Lead (Pb) in Workers highly Exposed to the Metal

Autor: Willian Robert Gomes, Paula Pícoli Devóz, Marilia Ladeira de Araújo, Gustavo Rafael Mazzaron Barcelos, Bruno Lemos Batista, Fernando Barbosa

Publikováno v: Biological Trace Element Research. 178:29-35

Lead (Pb) is a toxic metal, frequently associated with occupational exposure, due to its widespread use in industry and several studies have shown high Pb levels in workers occupationally exposed to the metal. The aim of this study was to evaluate th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f893b3d07063a5cb7cf0d2656a2f8ce2
https://doi.org/10.1007/s12011-016-0913-y

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Frequências de mutações CD39, IVS1-1, IVS1-6 e IVS1-110 em portadores de betatalassemia e suas influências nos valores hematimétricos

Autor: Juçara Gastaldi Cominal, Cristiane Fernandes de Freitas Tavares, Willian Robert Gomes, Raquel A. Santos

Publikováno v: Jornal Brasileiro de Patologia e Medicina Laboratorial, Volume: 53, Issue: 6, Pages: 362-367, Published: NOV 2017
Jornal Brasileiro de Patologia e Medicina Laboratorial v.53 n.6 2017
Jornal Brasileiro de Patologia e Medicina Laboratorial
Sociedade Brasileira de Patologia (SBP)
instacron:SBP
Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 53, Iss 6, Pp 362-367 (2017)

Introduction: Beta-thalassemia is caused by a deficient synthesis of the ß-chain of hemoglobin, which leads to a chronic, microcytic and hypochromic anemia. More than 200 mutations have already been associated with this type of thalassemia, and thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a365283b1e03d1b03f1a8bb9d9a0f73
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442017000600362&lng=en&tlng=en

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Lead (Pb) exposure induces disturbances in epigenetic status in workers exposed to this metal

Autor: Fernando Barbosa, Willian Robert Gomes, Tatiana Pedron, Paula Pícoli Devóz, Lusânia Maria Greggi Antunes, Bruno Lemos Batista, Marilia Ladeira de Araújo, Diego Luis Ribeiro, Gustavo Rafael Mazzaron Barcelos

Publikováno v: Journal of toxicology and environmental health. Part A. 80(19-21)

Previous studies showed that lead (Pb) exposure may modulate gene expression by changes in the epigenetic status. However, little is known about the impact of Pb exposure and alterations on DNA methylation patterns in humans exposed to this metal. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebddf8814d625e8b048768e65c391e18
https://pubmed.ncbi.nlm.nih.gov/28862539

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