Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Williamson Ritchie"'
Autor:
Bird Ian N, Price Caroline, Ward Malcolm A, Byers Helen L, Leung Kit-Yi, Derkinderen Pascal, Scales Timothy ME, Perera Timothy, Kellie Stuart, Williamson Ritchie, Anderton Brian H, Reynolds C Hugh
Publikováno v:
Molecular Neurodegeneration, Vol 6, Iss 1, p 12 (2011)
Abstract Background Tau protein is the principal component of the neurofibrillary tangles found in Alzheimer's disease, where it is hyperphosphorylated on serine and threonine residues, and recently phosphotyrosine has been demonstrated. The Src-fami
Externí odkaz:
https://doaj.org/article/6838724713484278996092d3711bd125
Autor:
Lynham Steven, Usardi Alessia, Hye Abdul, Abu Mika, Thompson Andrew J, Williamson Ritchie, Anderton Brian H, Hanger Diane P
Publikováno v:
BMC Neuroscience, Vol 11, Iss 1, p 120 (2010)
Abstract Background Membrane rafts are small highly dynamic sterol- and sphingolipid-enriched membrane domains that have received considerable attention due to their role in diverse cellular functions. More recently the involvement of membrane rafts
Externí odkaz:
https://doaj.org/article/64ad7d46f43a4404adc7fa47484e7837
Autor:
Bolanle, Israel O., Riches-Suman, Kirsten, Loubani, Mahmoud, Williamson, Ritchie, Palmer, Timothy M.
Publikováno v:
In Nutrition, Metabolism and Cardiovascular Diseases 6 May 2021 31(5):1349-1356
Yes
Cardiovascular diseases (CVDs) are the leading cause of death globally. While the major focus of pharmacological and non-pharmacological interventions has been on targeting disease pathophysiology and limiting predisposing factors, our under
Cardiovascular diseases (CVDs) are the leading cause of death globally. While the major focus of pharmacological and non-pharmacological interventions has been on targeting disease pathophysiology and limiting predisposing factors, our under
Externí odkaz:
http://hdl.handle.net/10454/18480
Yes
Motor neuron disease (MND) is a progressive neurodegenerative disease with no effective treatment. One of the principal pathological hallmarks is the deposition of TAR DNA binding protein 43 (TDP-43) in cytoplasmic inclusions. TDP-43 aggrega
Motor neuron disease (MND) is a progressive neurodegenerative disease with no effective treatment. One of the principal pathological hallmarks is the deposition of TAR DNA binding protein 43 (TDP-43) in cytoplasmic inclusions. TDP-43 aggrega
Externí odkaz:
http://hdl.handle.net/10454/17203
Autor:
Muha, V., Williamson, Ritchie, Hills, R., McNeilly, A.D., McWilliams, T.G., Alonso, J., Schimpl, M., Leney, A.C., Heck, A.J.R., Sutherland, C., Read, K.D., McCrimmon, R.J., Brooks, S.P., van Aalten, D.M.F.
Yes
O-GlcNAcylation is an abundant post-translational modification in the nervous system, linked to both neurodevelopmental and neurodegenerative disease. However, the mechanistic links between these phenotypes and site-specific O-GlcNAcylation
O-GlcNAcylation is an abundant post-translational modification in the nervous system, linked to both neurodevelopmental and neurodegenerative disease. However, the mechanistic links between these phenotypes and site-specific O-GlcNAcylation
Externí odkaz:
http://hdl.handle.net/10454/17525
Autor:
Weightman Potter, P.G., Vlachaki Walker, J.M., Robb, J.L., Chilton, J.K., Williamson, Ritchie, Randall, A.D., Ellacott, K.L.J., Beall, C.
Yes
Aims/hypothesis Hypoglycaemia is a major barrier to good glucose control in type 1 diabetes. Frequent hypoglycaemic episodes impair awareness of subsequent hypoglycaemic bouts. Neural changes underpinning awareness of hypoglycaemia are poorl
Aims/hypothesis Hypoglycaemia is a major barrier to good glucose control in type 1 diabetes. Frequent hypoglycaemic episodes impair awareness of subsequent hypoglycaemic bouts. Neural changes underpinning awareness of hypoglycaemia are poorl
Externí odkaz:
http://hdl.handle.net/10454/16628
Autor:
Selvan, N., Williamson, Ritchie, Mariappa, D., Campbell, D.G., Gourlay, R., Ferenbach, A.T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M., van Aalten, D.M.F.
Yes
Protein O-GlcNAcylation is a reversible post-translational modification of serines/threonines on nucleocytoplasmic proteins. It is cycled by the enzymes O-GlcNAc transferase (OGT) and O-GlcNAc hydrolase (O-GlcNAcase or OGA). Genetic approach
Protein O-GlcNAcylation is a reversible post-translational modification of serines/threonines on nucleocytoplasmic proteins. It is cycled by the enzymes O-GlcNAc transferase (OGT) and O-GlcNAc hydrolase (O-GlcNAcase or OGA). Genetic approach
Externí odkaz:
http://hdl.handle.net/10454/12133
Autor:
Grasso, L., Suska, O., Davidson, L., Gonatopolous-Pournatzis, T., Williamson, Ritchie, Wasmus, L., Wiedlich, S., Peggie, M., Stavridis, M.P., Cowling, V.H.
Yes
The mRNA cap stabilizes transcripts and recruits processing and translation factors. Grasso et al. report that the mRNA cap methyltransferase RNMTRAM is highly expressed in embryonic stem cells and is important for pluripotency-associated ge
The mRNA cap stabilizes transcripts and recruits processing and translation factors. Grasso et al. report that the mRNA cap methyltransferase RNMTRAM is highly expressed in embryonic stem cells and is important for pluripotency-associated ge
Externí odkaz:
http://hdl.handle.net/10454/8769
Autor:
Malik, Bilal, Fernandes, Cathy, Killick, Richard, Wroe, Richard, Usardi, Alessia, Williamson, Ritchie, Kellie, Stuart, Anderton, Brian H., Reynolds, C. Hugh
Publikováno v:
In Neurochemistry International August 2012 61(3):321-333