Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Williams Parsons"'
Autor:
Owen R. Hirschi, Stephanie A. Felker, Surya P. Rednam, Kelly L. Vallance, D. Williams Parsons, Angshumoy Roy, Gregory M. Cooper, Sharon E. Plon
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101850- (2024)
Purpose: Clinical variant analysis pipelines likely have poor sensitivity to the effects on splicing from variants beyond 10 to 20 bases of exon-intron boundaries. Here, we demonstrate the value of SpliceAI to inform curation of rare variants previou
Externí odkaz:
https://doaj.org/article/b1e1261f7f7d4684992f0aa6000961d8
Autor:
Owen Hirschi, Stephanie Felker, Surya Rednam, Kelly Vallance, D. Williams Parsons, Angshumoy Roy, Gregory Cooper, Sharon Plon
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100078- (2023)
Externí odkaz:
https://doaj.org/article/8c6f9f142fa34273b5c8029eeb07b95c
Autor:
Mari Kogiso, Lin Qi, Yuchen Du, Frank K. Braun, Huiyuan Zhang, L. Frank Huang, Lei Guo, Yulun Huang, Wan-Yee Teo, Holly Lindsay, Sibo Zhao, Sarah G. Injac, Zhen Liu, Vidya Mehta, Diep Tran, Feng Li, Patricia A. Baxter, Jack M. Su, Laszlo Perlaky, D. Williams Parsons, Murali Chintagumpala, Adekunle Adesina, Yongcheng Song, Xiao-Nan Li
Publikováno v:
Translational Oncology, Vol 18, Iss , Pp 101368- (2022)
Clinical outcomes in patients with WHO grade II/III astrocytoma, oligodendroglioma or secondary glioblastoma remain poor. Isocitrate dehydrogenase 1 (IDH1) is mutated in > 70% of these tumors, making it an attractive therapeutic target. To determine
Externí odkaz:
https://doaj.org/article/caa882369eb742c39053f6d150c8b83b
Autor:
D Williams, Parsons, Katherine A, Janeway, David R, Patton, Cynthia L, Winter, Brent, Coffey, P Mickey, Williams, Sinchita, Roy-Chowdhuri, Gregory J, Tsongalis, Mark, Routbort, Nilsa C, Ramirez, Lauren, Saguilig, Jin, Piao, Todd A, Alonzo, Stacey L, Berg, Elizabeth, Fox, Douglas S, Hawkins, Jeffrey S, Abrams, Margaret, Mooney, Naoko, Takebe, James V, Tricoli, Nita L, Seibel
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(20)
PURPOSE The National Cancer Institute–Children's Oncology Group Pediatric MATCH trial aimed to facilitate evaluation of molecular-targeted therapies in biomarker-selected cohorts of childhood and young adult patients with cancer by screening tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3189532393c9b3c1d67a9f7fb23d5c9e
https://pubmed.ncbi.nlm.nih.gov/35353553
https://pubmed.ncbi.nlm.nih.gov/35353553
Autor:
Olive S. Eckstein, Carl E. Allen, P. Mickey Williams, Sinchita Roy-Chowdhuri, David R. Patton, Brent Coffey, Joel M. Reid, Jin Piao, Lauren Saguilig, Todd A. Alonzo, Stacey L. Berg, Nilsa C. Ramirez, Alok Jaju, Joyce Mhlanga, Elizabeth Fox, Douglas S. Hawkins, Margaret M. Mooney, Naoko Takebe, James V. Tricoli, Katherine A. Janeway, Nita L. Seibel, D. Williams Parsons
Publikováno v:
Journal of Clinical Oncology. 40:2235-2245
PURPOSE The NCI-COG Pediatric MATCH trial assigns patients age 1-21 years with relapsed or refractory solid tumors, lymphomas, and histiocytic disorders to phase II studies of molecularly targeted therapies on the basis of detection of predefined gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fefec09e4b88fe8840a88cf929d3fb0
https://doi.org/10.1200/jco.21.02840
https://doi.org/10.1200/jco.21.02840
Autor:
Raghu Chandramohan, Jacquelyn Reuther, Ilavarasi Gandhi, Horatiu Voicu, Karla R. Alvarez, Sharon E. Plon, Dolores H. Lopez-Terrada, Kevin E. Fisher, D. Williams Parsons, Angshumoy Roy
Publikováno v:
J Mol Diagn
Somatic copy number alterations (SCNAs) in tumors are clinically significant diagnostic, prognostic, and predictive biomarkers. SCNA detection from targeted next-generation sequencing panels is increasingly common in clinical practice; however, detai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3f35d2541b8e9306f8e47973c26406
https://doi.org/10.1016/j.jmoldx.2022.03.011
https://doi.org/10.1016/j.jmoldx.2022.03.011
Autor:
Susan N Chi, Joanna S Yi, P Mickey Williams, Sinchita Roy-Chowdhuri, David R Patton, Brent D Coffey, Joel M Reid, Jin Piao, Lauren Saguilig, Todd A Alonzo, Stacey L Berg, Nilsa C Ramirez, Alok Jaju, Joyce C Mhlanga, Elizabeth Fox, Douglas S Hawkins, Margaret M Mooney, Naoko Takebe, James V Tricoli, Katherine A Janeway, Nita L Seibel, D Williams Parsons
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Background NCI-COG Pediatric MATCH assigns patients aged 1-21 years with refractory solid tumors, brain tumors, lymphomas, and histiocytic disorders to phase II trials of molecularly targeted therapies based on detection of pre-defined genetic altera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287b50580ea01adeaefb52fc91ae7354
https://doi.org/10.1093/jnci/djad085
https://doi.org/10.1093/jnci/djad085
Autor:
Stephen X. Skapek, D. Williams Parsons, Julia A. Bridge, Douglas S. Hawkins, Sheri L. Spunt, Jing Tian, Yueh-Yun Chi, Cheryl M. Coffin, Jennifer O. Black, Lin Xu, Angshumoy Roy, Theodore W. Laetsch
Supplementary Figures 1 and 2 Supplementary Figure 1: Representative photomicrographs of the spindle cell (A), round cell (B), and epithelioid (C) variants of undifferentiated sarcoma Supplementary Figure 2: GISTIC analysis of recurrent focal copy nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0fc4ceaa8df8f32013ea9cad44d055
https://doi.org/10.1158/1078-0432.22475025
https://doi.org/10.1158/1078-0432.22475025
Autor:
Stephen X. Skapek, D. Williams Parsons, Julia A. Bridge, Douglas S. Hawkins, Sheri L. Spunt, Jing Tian, Yueh-Yun Chi, Cheryl M. Coffin, Jennifer O. Black, Lin Xu, Angshumoy Roy, Theodore W. Laetsch
Purpose: A comprehensive analysis of the genomics of undifferentiated sarcomas (UDS) is lacking. We analyzed copy-number alterations and fusion status in patients with UDS prospectively treated on Children's Oncology Group protocol ARST0332.Experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d028482e7061524c6ae596007a2d863
https://doi.org/10.1158/1078-0432.c.6528975.v1
https://doi.org/10.1158/1078-0432.c.6528975.v1
Autor:
Annie Garcia, Lauren Desrosiers, Sarah Scollon, Stephanie Gruner, Jacquelyn Reuther, Ilavarasi Gandhi, Ninad Patil, Maren Y. Fuller, Hongzheng Dai, Donna Muzny, Richard A. Gibbs, Jennifer L. Bercaw-Pratt, Seema L. Rao, Nino Rainusso, Kevin E. Fisher, Frank Y. Lin, Sharon E. Plon, D. Williams Parsons, Angshumoy Roy
Publikováno v:
Cancer Genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edb4f233e3ae322aa54462bb2c2e3cc
https://doi.org/10.1016/j.cancergen.2022.01.001
https://doi.org/10.1016/j.cancergen.2022.01.001