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pro vyhledávání: '"Williamn R. Grove"'
Autor:
Sylvia Thomas, Williamn R. Grove, Laura Benson, Chetan D. Lathia, Nancy T. Sklarin, Avi I. Einzig, Javier Roca, Peter H. Wiernik
Publikováno v:
Investigational New Drugs. 15:235-246
CI-980 is a synthetic mitotic inhibitor that binds to the colchicine binding site of tubulin. It demonstrates broad activity against human and murine tumor models and shows no cross resistance with tumor models whose mechanism of resistance is mediat