Zobrazeno 1 - 10
of 62
pro vyhledávání: '"William Y. Wang"'
Autor:
Christopher D. Davidson, Firaol S. Midekssa, Samuel J. DePalma, Jordan L. Kamen, William Y. Wang, Danica Kristen P. Jayco, Megan E. Wieger, Brendon M. Baker
Publikováno v:
Advanced Science, Vol 11, Iss 3, Pp n/a-n/a (2024)
Abstract Intercellular communication is critical to the formation and homeostatic function of all tissues. Previous work has shown that cells can communicate mechanically via the transmission of cell‐generated forces through their surrounding extra
Externí odkaz:
https://doaj.org/article/566432448c1a431f9122f98512f580f9
Autor:
Xiaotian Tan, Kathleen C. Day, Xuzhou Li, Luke J. Broses, Wen Xue, Weishu Wu, William Y. Wang, Ting-Wen Lo, Emma Purcell, Sicong Wang, Yun-Lu Sun, Maung Kyaw Khaing Oo, Brendon M. Baker, Sunitha Nagrath, Mark L. Day, Xudong Fan
Publikováno v:
Biosensors and Bioelectronics: X, Vol 8, Iss , Pp 100066- (2021)
The functional membrane proteins on tumor-cell-derived EVs contain a large amount of biomolecular information, and can serve as a comprehensive marker to delineate the molecular nature of cancer. However, due to low secretion rates, it is difficult t
Externí odkaz:
https://doaj.org/article/f0e5c940854b43aa825d015c3ef79244
Autor:
Harrison L. Hiraki, Daniel L. Matera, William Y. Wang, Eashan S. Prabhu, Zane Zhang, Firaol Midekssa, Anna E. Argento, Johanna M. Buschhaus, Brock A. Humphries, Gary D. Luker, Abdon Pena-Francesch, Brendon M. Baker
Publikováno v:
Acta Biomater
The peritumoral stroma is a complex 3D tissue that provides cells with myriad biophysical and biochemical cues. Histologic observations suggest that during metastatic spread of carcinomas, these cues influence transformed epithelial cells, prompting
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
How cells migrate in fibrous tissues is still poorly understood. Here, with synthetic 3D fibre matrices of controlled alignment and stiffness, the authors report that cells in stiff matrices move slowly and continuously, but in softer, deformable mat
Externí odkaz:
https://doaj.org/article/b6d65b2bec4e4f619c3788aad89acbbf
Autor:
Mitra Aliabouzar, Oliver D. Kripfgans, William Y. Wang, Brendon M. Baker, J. Brian Fowlkes, Mario L. Fabiilli
Publikováno v:
Ultrasonics Sonochemistry, Vol 72, Iss , Pp 105430- (2021)
Acoustically-responsive scaffolds (ARSs), which are fibrin hydrogels containing monodispersed perfluorocarbon (PFC) emulsions, respond to ultrasound in an on-demand, spatiotemporally-controlled manner via a mechanism termed acoustic droplet vaporizat
Externí odkaz:
https://doaj.org/article/08029374d5ea4d98be29c2fe3779cded
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Angiogenesis is a complex, multicellular process that involves bidirectional interactions between extracellular matrix (ECM) and collectively invading endothelial cell (EC) sprouts that extend the microvasculature during development, wound healing, a
Externí odkaz:
https://doaj.org/article/bc0bf09351a14bddbdd2cbca979b1725
Autor:
William Y. Wang, Alexander T. Pearson, Matthew L. Kutys, Colin K. Choi, Michele A. Wozniak, Brendon M. Baker, Christopher S. Chen
Publikováno v:
APL Bioengineering, Vol 2, Iss 4, Pp 046107-046107-16 (2018)
Physical features of the extracellular matrix (ECM) heavily influence cell migration strategies and efficiency. Migration in and on fibrous ECMs is of significant physiologic importance, but limitations in the ability to experimentally define the dia
Externí odkaz:
https://doaj.org/article/56f268348fae474eb9f5b8221a8f8814
Publikováno v:
Nature Reviews Materials. 6:192-195
During fibrotic diseases, functional tissue parenchyma progressively transforms into stiff, disorganized and non-functional tissue causing organ failure. The underlying multitude of interconnected changes in the cellular microenvironment can be inves
Autor:
Brendon M. Baker, Andrew J. Putnam, David S. Cleveland, Yen Peng Kong, William Y. Wang, Emily A. Margolis, Jeffrey A. Beamish
Publikováno v:
Lab Chip
Supportive stromal cells of mesenchymal origins regulate vascular morphogenesis in developmental, pathological, and regenerative contexts, contributing to vessel formation, maturation, and long-term stability, in part via the secretion of bioactive m
Autor:
Brendon M. Baker, Danica Kristen P. Jayco, William Y. Wang, Harrison L Hiraki, Christopher D. Davidson, Daniel L. Matera, Samuel J. DePalma
Publikováno v:
Acta Biomater
Mechanical interactions between fibroblasts and their surrounding extracellular matrix (ECM) guide fundamental behaviors such as spreading, migration, and proliferation that underlie disease pathogenesis. The challenges of studying ECM mechanics in v