Zobrazeno 1 - 10
of 173
pro vyhledávání: '"William Wisden"'
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S30- (2023)
Externí odkaz:
https://doaj.org/article/73d0cd55f47b42168005a7719e5198d0
Autor:
Edward C. Harding, Wei Ba, Reesha Zahir, Xiao Yu, Raquel Yustos, Bryan Hsieh, Leda Lignos, Alexei L. Vyssotski, Florian T. Merkle, Timothy G. Constandinou, Nicholas P. Franks, William Wisden
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
When mice are exposed to external warmth, nitric oxide synthase (NOS1) neurons in the median and medial preoptic (MnPO/MPO) hypothalamus induce sleep and concomitant body cooling. However, how these neurons regulate baseline sleep and body temperatur
Externí odkaz:
https://doaj.org/article/d4fc4cfb68234854865556a8642d363b
Autor:
Polona Jager, Zhiwen Ye, Xiao Yu, Laskaro Zagoraiou, Hong-Ting Prekop, Juha Partanen, Thomas M. Jessell, William Wisden, Stephen G. Brickley, Alessio Delogu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The development and function of thalamic interneurons is only partially understood. Here the authors describe the unexpected mesencephalic origin of the GABAergic interneurons of the visual thalamus that provide both phasic and tonic modulation of th
Externí odkaz:
https://doaj.org/article/432c89f91322400da5e5343d56f414fe
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Mammals have evolved a range of behavioural and neurological mechanisms that coordinate cycles of thermoregulation and sleep. Whether diurnal or nocturnal, sleep onset and a reduction in core temperature occur together. Non-rapid eye movement (NREM)
Externí odkaz:
https://doaj.org/article/56c4cdb0ea294151bd89b224a89117a3
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
Sedatives target just a handful of receptors and ion channels. But we have no satisfying explanation for how activating these receptors produces sedation. In particular, do sedatives act at restricted brain locations and circuitries or more widely? T
Externí odkaz:
https://doaj.org/article/12cda8b3f77a4eae9c2ff5ee5d01a9a1
Autor:
Zhiwen Ye, Xiao Yu, Catriona M. Houston, Zahra Aboukhalil, Nicholas P. Franks, William Wisden, Stephen G. Brickley
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Cell-type specific differences in the kinetics of inhibitory postsynaptic conductance changes (IPSCs) are believed to impact upon network dynamics throughout the brain. Much attention has focused on how GABAA receptor (GABAAR) α and β subunit diver
Externí odkaz:
https://doaj.org/article/8edeeb08631d457ea0d55d54364e506a
Autor:
William Wisden
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 9 (2016)
On 22nd August 2016, the fields of molecular neurobiology and endocrinology lost one of their pioneers and true giants, Peter Seeburg, who died aged 72, a day after his birthday. His funeral ceremony took place in Heidelberg where he had worked since
Externí odkaz:
https://doaj.org/article/0e963ccaa9ee4b4d8c3269991b21ea76
Autor:
Elli Leppä, Anni-Maija Tuulikki Linden, M. Isabel Aller, Peer Wulff, Olga Vekovischeva, Bernhard Lüscher, Hartmut Lüddens, William Wisden, Esa R Korpi
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Endogenous neurosteroids and neuroactive steroids have potent and widespread actions on the brain via inhibitory GABAA receptors. In recombinant receptors and genetic mouse models their actions depend on the alpha, beta and delta subunits of the rece
Externí odkaz:
https://doaj.org/article/99d976fd8ef64a769f0f9c05c1069500
Autor:
Elena Frola, Annarita Patrizi, Thomas Goetz, Lucian Medrihan, Enrica Maria Petrini, Andrea Barberis, Peer Wulff, William Wisden, Marco Sassoè-Pognetto
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56311 (2013)
The neurotransmitter GABA regulates many aspects of inhibitory synapse development. We tested the hypothesis that GABAA receptors (GABAARs) work together with the synaptic adhesion molecule neuroligin 2 (NL2) to regulate synapse formation in differen
Externí odkaz:
https://doaj.org/article/863f60dbe04849b7a10bb3bb81ff1382
Autor:
Elli Leppä, Anni-Maija Linden, Olga Y Vekovischeva, Jerome D Swinny, Ville Rantanen, Esko Toppila, Harald Höger, Werner Sieghart, Peer Wulff, William Wisden, Esa R Korpi
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24159 (2011)
We investigated the behavioral significance of fast synaptic inhibition by αβγ2-type GABA(A) receptors on parvalbumin (Pv) cells. The GABA(A) receptor γ2 subunit gene was selectively inactivated in Pv-positive neurons by Cre/loxP recombination. T
Externí odkaz:
https://doaj.org/article/8f70cbd9fc3c41b1a21aa27753246945