Zobrazeno 1 - 10
of 30
pro vyhledávání: '"William W. Idler"'
The chemistry and structure of the epidermal α-keratin extracted from the skin of patients with a variety of disorders of keratinization have been investigated using biochemical, biophysical, and electron microscopic techniques developed for the cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b7831f54054b7667975a87226bf5930
https://doi.org/10.1159/000396303
https://doi.org/10.1159/000396303
Autor:
Shyh-Ing Jang, Karen M. Boeshans, Lindsay W. Black, Guihong Peng, Bijan Ahvazi, Lyuben N. Marekov, Fang Liu, William W. Idler
Publikováno v:
Protein Expression and Purification. 49:235-243
The study of bacteriophage T4 assembly has revealed regulatory mechanisms pertinent not only to viruses but also to macromolecular complexes. The capsid of bacteriophage T4 is composed of the major capsid protein gp23, and a minor capsid protein gp24
Autor:
Andrey E. Kalinin, Peter M. Steinert, Lyuben N. Marekov, William W. Idler, Peter McPhie, Blair Bowers, Alasdair C. Steven
Publikováno v:
Journal of Biological Chemistry. 279:22773-22780
Plakin family members envoplakin and periplakin have been shown to be part of the cornified cell envelope in terminally differentiating stratified squamous epithelia. In the present study, purified recombinant human envoplakin and periplakin were use
Autor:
William W. Idler, Ulrich Baxa, Bijan Ahvazi, Peter M. Steinert, Karen M. Boeshans, Fraydoon Rastinejad
Publikováno v:
Journal of Biological Chemistry. 279:7180-7192
Transglutaminase 3 (TGase 3) is a member of a family of Ca2+-dependent enzymes that catalyze covalent cross-linking reactions between proteins or peptides. TGase 3 isoform is widely expressed and is important for effective epithelial barrier formatio
Publikováno v:
Journal of Biological Chemistry. 278:23834-23841
The transglutaminase 3 enzyme is widely expressed in many tissues including epithelia. We have shown previously that it can bind three Ca2+ ions, which in site one is constitutively bound, while those in sites two and three are acquired during activa
Autor:
He Wang, Lyuben N. Marekov, David A.D. Parry, Peter M. Steinert, William W. Idler, Leslie N. Jones
Publikováno v:
The Journal of Cell Biology
Intermediate filaments (IF) have been recognized as ubiquitous components of the cytoskeletons of eukaryotic cells for 25 yr. Historically, the first IF proteins to be characterized were those from wool in the 1960s, when they were defined as low sul
Autor:
Lyuben N. Marekov, William W. Idler, Peter M. Steinert, Tonja Kartasova, Edit Tarcsa, Eleonora Candi
Publikováno v:
Journal of Biological Chemistry. 274:7226-7237
Small proline-rich 1 (SPR1) proteins are important for barrier function in stratified squamous epithelia. To explore their properties, we expressed in bacteria a recombinant human SPR1 protein and isolated native SPR1 proteins from cultured mouse ker
Autor:
Soo-Il Chung, William W. Idler, Lyuben N. Marekov, Edit Tarcsa, Peter M. Steinert, Eleonora Candi, Jeanne M. Andreoli
Publikováno v:
Journal of Biological Chemistry. 272:27893-27901
Trichohyalin (THH) is a major structural protein of the inner root sheath cells and medulla layer of the hair follicle and, to a lesser extent, of other specialized epithelia. THH is a high molecular weight insoluble α-helix-rich protein that forms
Autor:
Kozo Yoneda, Ming Hai Wang, K U Cehrs, William W. Idler, Peter M. Steinert, O W McBride, Daniel Hohl
Publikováno v:
Journal of Biological Chemistry. 267:18060-18066
Loricrin is the major protein component of the cornified cell envelope of terminally differentiated mammalian epidermal (stratum corneum) cells. Using a specific human cDNA clone, we have isolated and characterized the human loricrin gene. We show th
Publikováno v:
Journal of Biological Chemistry. 267:7710-7717
Membrane-associated transglutaminases (TGase1) have recently been found to be common in mammalian cells, but it is not clear whether these derive from the same or different genes. In order to determine the complexity of this system, we have isolated