Zobrazeno 1 - 10
of 78
pro vyhledávání: '"William W. Du"'
Autor:
William W. Du, Chi Zhou, Hui Yang, Shuoyang Wen, Yu Chen, Eric X. Chen, Xiuwei H. Yang, Feiya Li, Kevin Y. Du, Hui Yuan, Ting Ye, Javeria Qadir, Burton B. Yang
Publikováno v:
Research, Vol 7 (2024)
Colitis is a chronic bowel disease characterized by damage to the lining of the large intestine, with its precise underlying causes remaining incompletely understood. In this study, we provide evidence that circular RNA circNlgn plays a pivotal role
Externí odkaz:
https://doaj.org/article/0cd0199ab161448a9e670d091141a477
Autor:
Feiya Li, William W. Du, Xiangmin Li, Jindong Xu, Nan Wu, Faryal Mehwish Awan, Yang Yang, Fariborz Asghari Alashti, Sheng Wang, Burton B. Yang
Publikováno v:
Research, Vol 7 (2024)
Recent studies have highlighted the pivotal roles of circular RNAs (circRNAs) in cardiovascular diseases. Through high-throughput circRNA sequencing of both normal myocardial tissues and hypertrophic patients, we unveiled 32,034 previously undiscover
Externí odkaz:
https://doaj.org/article/2926c60ad7fe4c7a8c06edbbe747a6f3
Publikováno v:
Advanced Science, Vol 10, Iss 28, Pp n/a-n/a (2023)
Abstract Current studies on actin function primarily rely on cytoplasmic actin due to the absence of cellular models specifically expressing nuclear actin. Here, cell models capable of expressing varying levels of nuclear F/G‐actin are generated an
Externí odkaz:
https://doaj.org/article/cc9bd908e2e74f49ac6bc8c39f7a138d
Autor:
Jindong Xu, William W. Du, Nan Wu, Feiya Li, Xiangmin Li, Yizhen Xie, Sheng Wang, Burton B. Yang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 175-189 (2022)
Doxorubicin is a chemotherapeutic medication commonly used to treat many types of cancers, but it has side effects including vomiting, rash, hair loss, and bone marrow suppression. The most dangerous side effects are cardiomyopathy, cardiofibrosis, a
Externí odkaz:
https://doaj.org/article/0b4112b1038842898e34d80c6ea46305
Autor:
William W. Du, Xiangmin Li, Jian Ma, Ling Fang, Nan Wu, Feiya Li, Preet Dhaliwal, Weining Yang, Albert J. Yee, Burton B. Yang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 276-292 (2022)
We performed in vitro and in vivo experiments to investigate the role of the circular RNA circSKA3 in tumor development. We examined the effects of circSKA3 on mediating breast cancer metastasis. In vitro, we found that the circular RNA circSKA3 was
Externí odkaz:
https://doaj.org/article/9adcecc5033845dbab93a54bd5fa6f4f
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101702- (2022)
Summary: Due to the unique structure of circular RNAs, it is challenging to use traditional pulldown approaches. Here, we describe the design and use of a probe that spans the back splicing junction (BSJ), enabling interaction with circular RNAs. The
Externí odkaz:
https://doaj.org/article/e66caa3d4ba5476ea7d42e1431a3c8fa
Autor:
Chao Zhang, RongFang Ding, YiCheng Sun, Si Tong Huo, Alina He, Chang Wen, HongHao Chen, William W. Du, WeiNan Lai, Huijun Wang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 1243-1257 (2021)
Circular RNAs (circRNAs) are a type of endogenous non-coding RNA that were discovered to regulate gene expression through multiple pathways. Metastasis remains one of the biggest obstacles in cancer treatment. In this review, we focus on circRNAs inv
Externí odkaz:
https://doaj.org/article/94df62f153354a32933d01391aeac8b7
Autor:
Chao Zhang, Si Tong Huo, Zhiyong Wu, Lina Chen, Chang Wen, Honghao Chen, William W. Du, Nan Wu, Daogang Guan, Sen Lian, Burton B. Yang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 568-576 (2020)
Circular RNAs (circRNAs) are circularized, single-stranded RNAs that are covalently linked. With their abundance in tissues and developmental stage-specific expression, circRNAs participate in a variety of physiological and pathological processes. In
Externí odkaz:
https://doaj.org/article/4380ff5af49f43bca3fd858ade28925f
Autor:
Nan Wu, Albert Yee, Ling Fang, Jian Ma, Burton B. Yang, Kaixuan Zeng, William W. Du, Juanjuan Lyu
Publikováno v:
Mol Ther
Circular RNAs (circRNAs) represent a large group of non-coding RNAs that are widely detected in mammalian cells. Although most circRNAs are generated in a sense orientation, there is a group of circRNAs that are synthesized in an antisense orientatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d02a5d14304cc6c596bbf833c6aeae3
https://doi.org/10.1016/j.ymthe.2021.08.002
https://doi.org/10.1016/j.ymthe.2021.08.002
Autor:
Nan Wu, Feiya Li, Weining Yang, William W. Du, Faryal Mehwish Awan, Chao Zhang, Juanjuan Lyu, Sema Misir, Kaixuan Zeng, Esra Eshaghi, Burton B. Yang
Publikováno v:
Molecular Therapy.
Circular RNAs (circRNAs) are a group of non-coding RNAs with a unique circular structure generated by back-splicing. It is acknowledged that circRNAs play critical roles in cardiovascular diseases. However, functional studies of circRNAs were impeded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2170e40b4cadd70dd098138667a6acc1
https://doi.org/10.1016/j.ymthe.2022.10.005
https://doi.org/10.1016/j.ymthe.2022.10.005