Zobrazeno 1 - 10
of 152
pro vyhledávání: '"William W. Cruikshank"'
Autor:
Timothy R D J Radstake, Lenny van Bon, Jasper Broen, Mark Wenink, Kim Santegoets, Yanhui Deng, Anila Hussaini, Robert Simms, William W Cruikshank, Robert Lafyatis
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5981 (2009)
BACKGROUND:Regulatory T cells (Tregs) are essential in the control of tolerance. Evidence implicates Tregs in human autoimmune conditions. Here we investigated their role in systemic sclerosis (SSc). METHODS/PRINCIPAL FINDINGS:Patients were subdivide
Externí odkaz:
https://doaj.org/article/0c5f8119f00c4c17bbcadd9eefc6c35a
Autor:
Charlotte E. Cheadle, Marina Tuzova, George T. O'Connor, Scott T. Weiss, Catherine M. Hawrylowicz, Paul E Pfeffer, Eve Hornsby, William W. Cruikshank, Augusto A. Litonjua, Nancy Laranjo, Vincent J. Carey
Publikováno v:
Bone Abstracts.
Autor:
Kovilen Sawmynaden, Mark D. Carr, Gareth Hall, Debra L. Taylor, Eilish Cullen, Richard Cowan, Richard Bayliss, Simon Fox, Catherine A. Kettleborough, Frederick W. Muskett, William W. Cruikshank, David Matthews, Andrew Merritt, Joanne Arnold
Publikováno v:
Journal of Biological Chemistry. 291:16840-16848
Interleukin-16 (IL-16) is reported to be a chemoattractant cytokine and modulator of T-cell activation, and has been proposed as a ligand for the co-receptor CD4. The secreted active form of IL-16 has been detected at sites of TH1-mediated inflammati
Autor:
Leonard B. Bacharier, George T. O'Connor, James E. Gern, Katy F. Jaffee, Wayne G. Shreffler, William W. Cruikshank, Melissa S. Burger, Frank R. Witter, Sujani Kakumanu, Cynthia M. Visness, Amy Dresen
Publikováno v:
Immunity, Inflammation and Disease
Asthma in the inner‐city population is usually atopic in nature, and is associated with significant morbidity and mortality. However, the underlying immune abnormalities that underlie asthma in urban adults have not been well defined. We investigat
Autor:
Harley Y. Tse, Paul C. Montgomery, William W. Cruikshank, Robert P. Lisak, Dusanka S Skundric
Publikováno v:
Cytokine. 75:234-248
Cytokines are pleiotropic soluble mediators of cellular functions. Cytokines are critical in immune pathogenesis of human diseases, including autoimmune CD4(+) T cell mediated chronic inflammatory, demyelinating and neurodegenerative diseases of the
Autor:
Henry Lynn, Amy Dresen, Leonard B. Bacharier, George T. O'Connor, William W. Cruikshank, Diane R. Gold, Meyer Kattan, Peter J. Gergen, Hugh A. Sampson, Megan Sandel, Howard M. Lederman, Katy F. Jaffee, Gordon R. Bloomberg, Robert A. Wood, Wayne G. Shreffler, James E. Gern, Agustin Calatroni
Background Disadvantaged urban children have high rates of allergic diseases and wheezing, which are diseases associated with type 2–biased immunity. Objective We sought to determine whether environmental exposures in early life influence cytokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79506f05a0dc75f7fe2d49ad0b1d6a5b
https://europepmc.org/articles/PMC5509531/
https://europepmc.org/articles/PMC5509531/
Autor:
Sumati Ram-Mohan, Linh Aven, Ramaswamy Krishnan, Rebecca Achey, Alan Fine, Xingbin Ai, William W. Cruikshank, Jesus Paez-Cortez
Publikováno v:
The FASEB Journal. 28:897-907
Children who are exposed to environmental respiratory insults often develop asthma that persists into adulthood. In this study, we used a neonatal mouse model of ovalbumin (OVA)-induced allergic airway inflammation to understand the long-term effects
Publikováno v:
The Journal of Immunology. 189:5886-5895
Chemokine receptor cross-desensitization provides an important mechanism to regulate immune cell recruitment at sites of inflammation. We previously reported that the mycobacterial cell wall glycophospholipid mannose-capped lipoarabinomannan (ManLAM)
Autor:
Marina Tuzova, Wai Ming Lee, Katy F. Jaffee, Alkis Togias, Cynthia M. Visness, Carin I. Lamm, William W. Cruikshank, James E. Gern, Gordon R. Bloomberg, Tressa Pappas, Robert A. Wood, Robert F. Lemanske
Publikováno v:
The Journal of Infectious Diseases
Background. The risk of developing childhood asthma has been linked to the severity and etiology of viral respiratory illnesses in early childhood. Since inner-city infants have unique environmental exposures, we hypothesized that patterns of respira
Autor:
Begoña Ruiz-Perez, Marina Tuzova, Paul K. Wallace, Howard M. Lederman, Ngoc P. Ly, Rachel M. McLoughlin, Gordon R. Bloomberg, Agustin Calatroni, Diane R. Gold, James E. Gern, Cynthia M. Visness, William W. Cruikshank, Meyer Kattan
Publikováno v:
Clinical & Experimental Allergy. 42:392-404
SummaryBackground Immunomodulatory T cells are thought to influence development of allergy and asthma, but early life longitudinal data on their phenotype and function are lacking. Objectives As part of the Urban Environment and Childhood Asthma (URE