Zobrazeno 1 - 10
of 14
pro vyhledávání: '"William W. Branford"'
Autor:
H. Joseph Yost, Deborah W. Neklason, I-Chun Tsai, Randall W. Burt, David M. Virshup, Margaret F. Woolf, William W. Branford
Publikováno v:
International Journal of Cancer. 120:1005-1012
The Wnt signaling pathway is critical for embryonic development and is dysregulated in multiple cancers. Two closely related isoforms of casein kinase I (CKIdelta and epsilon) are positive regulators of this pathway. We speculated that mutations in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8a11c9d0e9bd179572b45776943f9e
https://doi.org/10.1002/ijc.22368
https://doi.org/10.1002/ijc.22368
Autor:
William W. Branford, H. Joseph Yost
Publikováno v:
Current Biology. 12:2136-2141
During gastrulation, diffusible "organizer" signals, including members of the TGFβ Nodal subfamily [1], pattern dorsal mesoderm and the embryonic axes. Simultaneously, negative regulators of these signals, including the Nodal inhibitor Lefty, an aty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d38013c98fe8b085eed74e3fe4c949
https://doi.org/10.1016/s0960-9822(02)01360-x
https://doi.org/10.1016/s0960-9822(02)01360-x
Publikováno v:
Developmental Biology. 224:373-387
Hox genes show related sequences and overlapping expression domains that often reflect functional redundancy as well as a common evolutionary origin. To accurately define their functions, it has become necessary to compare phenotypes of mice with sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee19098a6ecf41e986e68f8fb2dce54
https://doi.org/10.1006/dbio.2000.9809
https://doi.org/10.1006/dbio.2000.9809
Publikováno v:
Developmental Biology. 223:291-306
The Lefty subfamily of TGFbeta signaling molecules has been implicated in early development in mouse, zebrafish, and chick. Here, we show that Xenopus lefty (Xlefty) is expressed both bilaterally in symmetric midline domains and unilaterally in left
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3043ed5b3fdb1e9a21ed464325bb7c
https://doi.org/10.1006/dbio.2000.9739
https://doi.org/10.1006/dbio.2000.9739
Publikováno v:
Development. 127:1081-1093
The pitx2 gene is a member of the bicoid-homeodomain class of transcription factors that has been implicated in the control of left-right asymmetry during organogenesis. Here we demonstrate that in zebrafish there are two pitx2 isoforms, pitx2a and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51b275c1ccc1d4ed3142b8c93efeb4d
https://doi.org/10.1242/dev.127.5.1081
https://doi.org/10.1242/dev.127.5.1081
Autor:
S. Steven Potter, William W. Branford
Publikováno v:
Mammalian Genome. 9:799-806
We previously described the existence of abundant, processed, polyadenylated murine Hoxa 11 antisense transcripts. Of particular interest, in the developing limbs the antisense transcripts were observed to be present in a pattern complementary to tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea492549b68733fe639bb42d49100c2
https://doi.org/10.1007/s003359900870
https://doi.org/10.1007/s003359900870
Autor:
M Weinstein, M T Valerius, S. Steven Potter, G Q Zhao, E H Birkenmeier, L B Rowe, William W. Branford
Publikováno v:
Mechanisms of Development. 65(1-2):87-98
Spx1, a novel mouse homeobox gene, encodes a homeodomain characteristic of the paired-like class of homeobox genes and has been mapped to the distal end of the X chromosome. Northern blot hybridization of adult tissues detected high levels of a singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cffd34f80971e7528eb68aefe7a9935
Publikováno v:
Developmental Biology. 176(2):284-299
We report the cloning, characterization, and targeting of an Sp1-related zinc finger transcription factor gene from the distal arm of mouse chromosome 12. This gene, previously identified in rats and humans and designated sp4, is homologous to the Dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c5f92bf351f681317d9a6f10f218ed
Autor:
H. Joseph Yost, William W. Branford
Publikováno v:
Current Biology. 14:R341-R343
The secreted TGFβ factor Lefty antagonizes Nodal signaling during vertebrate embryogenesis, but how it does so has been a mystery. Recent analyses have elucidated the molecular mechanisms underlying this function of Lefty.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd28615e7908165162908d2e792fca2
https://doi.org/10.1016/j.cub.2004.04.020
https://doi.org/10.1016/j.cub.2004.04.020
Publikováno v:
Mechanisms of Development. 52:291-303
To begin to define the genetic network involved in cardiogenesis, we generated mice bearing the alpha-myosin heavy chain (MHC)-Hoxb-7 transgene. We hypothesized that using the cardiac-specific alpha-MHC promoter, we can direct ectopic expression of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91ada80e5498d197f0e80adad5b646d
https://doi.org/10.1016/0925-4773(95)98114-p
https://doi.org/10.1016/0925-4773(95)98114-p