Zobrazeno 1 - 10
of 151
pro vyhledávání: '"William W, Fisher"'
Autor:
Justin A. Bosch, Nathan Keith, Felipe Escobedo, William W. Fisher, James Thai LaGraff, Jorden Rabasco, Kenneth H. Wan, Richard Weiszmann, Yulun Wu, Yanhui Hu, Shu Kondo, James B. Brown, Norbert Perrimon, Susan E. Celniker
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113737- (2024)
Externí odkaz:
https://doaj.org/article/9482914255e4447581d2f70f57d2085e
Autor:
Justin A. Bosch, Nathan Keith, Felipe Escobedo, William W. Fisher, James Thai LaGraff, Jorden Rabasco, Kenneth H. Wan, Richard Weiszmann, Yanhui Hu, Shu Kondo, James B. Brown, Norbert Perrimon, Susan E. Celniker
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113311- (2023)
Summary: Short polypeptides encoded by small open reading frames (smORFs) are ubiquitously found in eukaryotic genomes and are important regulators of physiology, development, and mitochondrial processes. Here, we focus on a subset of 298 smORFs that
Externí odkaz:
https://doaj.org/article/4b08ef18ffc94b6b89b291356102f40d
Autor:
James B. Brown, Sasha A. Langley, Antoine M. Snijders, Kenneth H. Wan, Siti Nur Sarah Morris, Benjamin W. Booth, William W. Fisher, Ann S. Hammonds, Soo Park, Richard Weiszmann, Charles Yu, Jennifer A. Kirwan, Ralf J. M. Weber, Mark R. Viant, Jian-Hua Mao, Susan E. Celniker
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Brown et al. apply integrated omics and phenotypic screening to assess the role of the gut microbiome in modulating host resilience in Drosophila melanogaster. They find that Acetobacter tropicalis in gnotobiotic animals, is sufficient to rescue incr
Externí odkaz:
https://doaj.org/article/c3ab3d12ed36490693a2a628de744736
Autor:
Benjamin W. Booth, Charles McParland, Keith Beattie, William W. Fisher, Ann S. Hammonds, Susan E. Celniker, Erwin Frise
Publikováno v:
iScience, Vol 2, Iss , Pp 136-140 (2018)
Summary: High-content image acquisition is generally limited to cells grown in culture, requiring complex hardware and preset imaging modalities. Here we report an open source software package, OpenHiCAMM (Open Hi Content Acquisition for μManager),
Externí odkaz:
https://doaj.org/article/941e1a2272bc4dd9a0848d5053697ec6
Autor:
Jian-Hua Mao, Siti Nur Sarah Morris, Susan E. Celniker, James B. Brown, William W. Fisher, Kenneth H. Wan, Richard Weiszmann, Mark R. Viant, Benjamin W. Booth, Charles Yu, Soo Park, Ann S. Hammonds, Jennifer A. Kirwan, Sasha A. Langley, Antoine M. Snijders, Ralf J. M. Weber
Publikováno v:
Communications biology, vol 4, iss 1
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
The gut microbiome produces vitamins, nutrients, and neurotransmitters, and helps to modulate the host immune system—and also plays a major role in the metabolism of many exogenous compounds, including drugs and chemical toxicants. However, the ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1ffdcd0acbb5a2b1dcf15bed1102fc
https://escholarship.org/uc/item/15g832nr
https://escholarship.org/uc/item/15g832nr
Autor:
William W. Fisher, Benjamin W. Booth, Susan E. Celniker, Keith Beattie, Ann S. Hammonds, Erwin Frise, C. P. McParland
Publikováno v:
iScience, Vol 2, Iss, Pp 136-140 (2018)
iScience
Booth, BW; McParland, C; Beattie, K; Fisher, WW; Hammonds, AS; Celniker, SE; et al.(2018). OpenHiCAMM: High-Content Screening Software for Complex Microscope Imaging Workflows.. iScience, 2, 136-140. doi: 10.1016/j.isci.2018.03.017. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/6c90r2zx
iScience
Booth, BW; McParland, C; Beattie, K; Fisher, WW; Hammonds, AS; Celniker, SE; et al.(2018). OpenHiCAMM: High-Content Screening Software for Complex Microscope Imaging Workflows.. iScience, 2, 136-140. doi: 10.1016/j.isci.2018.03.017. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/6c90r2zx
SUMMARY High-content image acquisition is generally limited to cells grown in culture, requiring complex hardware and preset imaging modalities. Here we report an open source software package, OpenHiCAMM (Open Hi Content Acquisition for μManager), t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0eb1c47bb0b7df56805ef41514ed037
https://doi.org/10.1016/j.isci.2018.03.017
https://doi.org/10.1016/j.isci.2018.03.017
Autor:
LaDeana W. Hillier, Mitch Corson, Martha Wall, D. Vafeados, Alec Victorsen, Robert H. Waterston, Robert Terrell, William W. Fisher, Susan E. Celniker, David Steffen, Matt Kirkey, Ann S. Hammonds, Koon-Kiu Yan, Mark Gerstein, Haneen N. Ammouri, Swapna Samanta, Samantha Seabrook-Sturgis, Madhura Kadaba, Lijia Ma, Soo Park, Jeffery Gersch, Matt Szynkarek, Michelle M. Kudron, Mei Han, Valerie Reinke, Kevin P. White, Jennifer L. Moran, Timothy Durham, Louis Gevirtzman, Jinrui Xu, Jaeda Patton, Nader Jameel
Publikováno v:
Genetics. 208:937-949
The model organism Encylopedia of Regulatory Elements (modERN) project was designed to generate genome-wide binding profiles for the majority of transcription... To develop a catalog of regulatory sites in two major model organisms, Drosophila melano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b85e8febc2794113aef533cfcd00cd9a
https://doi.org/10.1534/genetics.117.300657
https://doi.org/10.1534/genetics.117.300657
Autor:
Margaret C W Ho, Holly Johnsen, Sara E Goetz, Benjamin J Schiller, Esther Bae, Diana A Tran, Andrey S Shur, John M Allen, Christoph Rau, Welcome Bender, William W Fisher, Susan E Celniker, Robert A Drewell
Publikováno v:
PLoS Genetics, Vol 5, Iss 11, p e1000709 (2009)
It is a long-held belief in evolutionary biology that the rate of molecular evolution for a given DNA sequence is inversely related to the level of functional constraint. This belief holds true for the protein-coding homeotic (Hox) genes originally d
Externí odkaz:
https://doaj.org/article/54818f7f8677431098ff351f308d7890
Autor:
Clara Henriquez, Hamutal Arbel, Mark D. Biggin, Susan E. Celniker, Kenneth H. Wan, James B. Brown, Sumanta Basu, Soo Park, Peter J. Bickel, Richard Weiszmann, Benjamin W. Booth, Ann S. Hammonds, Omid Shams Solari, William W. Fisher, Soile V.E. Keranen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 3
Proceedings of the National Academy of Sciences of the United States of America
Arbel, H; Basu, S; Fisher, WW; Hammonds, AS; Wan, KH; Park, S; et al.(2019). Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy. Proceedings of the National Academy of Sciences of the United States of America, 116(3), 900-908. doi: 10.1073/pnas.1808833115. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/6jt200hj
Proceedings of the National Academy of Sciences of the United States of America
Arbel, H; Basu, S; Fisher, WW; Hammonds, AS; Wan, KH; Park, S; et al.(2019). Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy. Proceedings of the National Academy of Sciences of the United States of America, 116(3), 900-908. doi: 10.1073/pnas.1808833115. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/6jt200hj
Significance We demonstrate a high-accuracy method for predicting enhancers genome-wide with >85% precision as validated by transgenic reporter assays in Drosophila embryos. This accuracy in a metazoan system enables us to predict with high confidenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a35a0f230f22332bdb66c91afb2e914
https://escholarship.org/uc/item/6jt200hj
https://escholarship.org/uc/item/6jt200hj
Autor:
Richard Weiszmann, Soo Park, Clara Henriquez, Hamutal Arbel, Peter J. Bickel, Omid Shams Solari, Susan E. Celniker, Kenneth H. Wan, Mark D. Biggin, James B. Brown, Soile V.E. Keranen, William W. Fisher, Ann S. Hammonds
Identifying functional enhancers elements in metazoan systems is a major challenge. For example, large-scale validation of enhancers predicted by ENCODE reveal false positive rates of at least 70%. Here we use the pregrastrula patterning network ofDr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e815b9560030612aff673afc2fac389d