Zobrazeno 1 - 10
of 328
pro vyhledávání: '"William Tyler"'
Autor:
Colton Ladbury, Claire Hao, William Tyler Watkins, Sagus Sampath, Jeffrey Wong, Arya Amini, Karen Sokolov, Jekwon Yeh, Karine A. Al Feghali, Dorine de Jong, Arjun Maniyedath, Shervin Shirvani, Liana Nikolaenko, Matthew Mei, Alex Herrera, Leslie Popplewell, Lihua Elizabeth Budde, Savita Dandapani
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Purpose/objective(s)Bridging radiation therapy (bRT) is increasingly being utilized prior to chimeric antigen receptor (CAR) T-cell therapy for large B-cell lymphoma (LBCL). It is unknown how the extent of cytoreduction during bRT impacts outcomes.Ma
Externí odkaz:
https://doaj.org/article/502c60fc675a43be8a7a55a5466af5ee
Autor:
William Tyler Frantz, Sharanya Iyengar, James Neiswender, Alyssa Cousineau, René Maehr, Craig J Ceol
Publikováno v:
eLife, Vol 12 (2023)
Tissue-resident stem and progenitor cells are present in many adult organs, where they are important for organ homeostasis and repair in response to injury. However, the signals that activate these cells and the mechanisms governing how these cells r
Externí odkaz:
https://doaj.org/article/609c615bf2e64daebd889405e7b64582
Autor:
Stanley I. Gutiontov, William Tyler Turchan, Liam F. Spurr, Sherin J. Rouhani, Carolina Soto Chervin, George Steinhardt, Angela M. Lager, Pankhuri Wanjari, Renuka Malik, Philip P. Connell, Steven J. Chmura, Aditya Juloori, Philip C. Hoffman, Mark K. Ferguson, Jessica S. Donington, Jyoti D. Patel, Everett E. Vokes, Ralph R. Weichselbaum, Christine M. Bestvina, Jeremy P. Segal, Sean P. Pitroda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Immune checkpoint blockade (ICB) improves outcomes in non-small cell lung cancer (NSCLC) though most patients progress. There are limited data regarding molecular predictors of progression. In particular, there is controversy regarding the r
Externí odkaz:
https://doaj.org/article/82195ffa5c7b45b097938796d4698839
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeTo evaluate the accuracy and efficiency of Artificial-Intelligence (AI) segmentation in Total Marrow Irradiation (TMI) including contours throughout the head and neck (H&N), thorax, abdomen, and pelvis.MethodsAn AI segmentation software was cl
Externí odkaz:
https://doaj.org/article/a0dea122029e4049a5ec1a9cdd9cf985
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 27, Iss , Pp 100782- (2022)
The utility of radiotherapy as a means of palliating symptoms due to metastatic cancer is well-accepted. A growing body of literature suggests that radiotherapy may play a role beyond palliation in some patients with low-burden metastatic disease. Re
Externí odkaz:
https://doaj.org/article/b583aa6d0f184b8eb2fe1d389dc5838d
Publikováno v:
Advances in Radiation Oncology, Vol 5, Iss 2, Pp 279-288 (2020)
Purpose: To introduce multiobjective, multidelivery optimization (MODO), which generates alternative patient-specific plans emphasizing dosimetric trade-offs and conformance to quasi-constrained (QC) conditions for multiple delivery techniques. Metho
Externí odkaz:
https://doaj.org/article/90f1c7140fde4d8e872ea216f0f08f17
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9573 (2021)
Radiotherapy and immunotherapy are most effective as cancer therapies in the setting of low-volume disease. Although initial studies of radio-immunotherapy in patients with metastatic cancer have not confirmed the efficacy of this approach, the role
Externí odkaz:
https://doaj.org/article/6b36214f74154375a8c07aed3430e08e
Autor:
Deepa Sharma, Anoja Giles, Amr Hashim, Jodi Yip, Yipeng Ji, Natalie Ngoc Anh Do, Juliana Sebastiani, William Tyler Tran, Golnaz Farhat, Michael Oelze, Gregory J Czarnota
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226475 (2019)
It is now well established that for tumour growth and survival, tumour vasculature is an important element. Studies have demonstrated that ultrasound-stimulated microbubble (USMB) treatment causes extensive endothelial cell death leading to tumour va
Externí odkaz:
https://doaj.org/article/5ef39ea9a7ff4ced8e124461bc1d25cf
Autor:
William Tyler Frantz, Craig J Ceol
Publikováno v:
Cells, Vol 9, Iss 5, p 1289 (2020)
Melanoma is the deadliest form of skin cancer and one of few cancers with a growing incidence. A thorough understanding of its pathogenesis is fundamental to developing new strategies to combat mortality and morbidity. Zebrafish—due in large part t
Externí odkaz:
https://doaj.org/article/0590edd066bc41f38812168aee2b59e6
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 3, Pp 363-372 (2014)
Tumor radiation resistance poses a major obstacle in achieving an optimal outcome in radiation therapy. In the current study, we characterize a novel therapeutic approach that combines ultrasound-driven microbubbles with radiation to increase treatme
Externí odkaz:
https://doaj.org/article/1d6b75946af44096a95930b7912549e1