Zobrazeno 1 - 10
of 12
pro vyhledávání: '"William T. Choi"'
Autor:
Prasanna Kandel, Tipwarin Phongmekhin, Lyra Chang, Nick Matinyan, Fatih Semerci, Austin C. Cao, Eva Estébanez-Perpiñá, Mirjana Maletic-Savatic, Damian W. Young, Aleksandar Bajić, Kevin Chen, Idris O. Raji, Pablo Fuentes-Prior, David D. Moore, Caroline L. Benn, Lihua Ma, Alba Jiménez-Panizo, Koen J. T. Venken, Kevin R. MacKenzie, William T. Choi, Dodge L. Baluya, Srinivas Chamakuri
Adult hippocampal neurogenesis underpins learning, memory, and mood, but diminishes with age and illness. The orphan nuclear receptor TLX/NR2E1 is known to regulate neural stem and progenitor cell self-renewal and proliferation, but the precise mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a53a65999341b9231564b1ae4d58864e
https://doi.org/10.1101/2020.10.28.359810
https://doi.org/10.1101/2020.10.28.359810
Autor:
Mehmet Tosun, Zhandong Liu, Cemal Karakas, Mirjana Maletic-Savatic, Hyun-Hwan Jeong, Fatih Semerci, William T. Choi
Publikováno v:
BMC Systems Biology
BMC Systems Biology, Vol 12, Iss S8, Pp 77-88 (2018)
BMC Systems Biology, Vol 12, Iss S8, Pp 77-88 (2018)
Background The mammalian brain is organized into regions with specific biological functions and properties. These regions have distinct transcriptomes, but little is known whether they may also differ in their metabolome. The metabolome, a collection
Autor:
Christine, Tang, Kevin, Chen, Aleksandar, Bajic, William T, Choi, Dodge L, Baluya, Mirjana, Maletic-Savatic
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1842
Over the past decade, advances in systems biology or 'omics techniques have enabled unprecedented insights into the biological processes that occur in cells, tissues, and on the organism level. One of these technologies is the metabolomics, which exa
Autor:
Kevin Chen, Aleksandar Bajić, Christine Tang, Dodge L. Baluya, William T. Choi, Mirjana Maletic-Savatic
Publikováno v:
Somatic Stem Cells ISBN: 9781493986965
Over the past decade, advances in systems biology or 'omics techniques have enabled unprecedented insights into the biological processes that occur in cells, tissues, and on the organism level. One of these technologies is the metabolomics, which exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73d3041424e8bd8f5f39959f52a7cd27
https://doi.org/10.1007/978-1-4939-8697-2_20
https://doi.org/10.1007/978-1-4939-8697-2_20
Publikováno v:
Frontiers in Biology. 10:141-153
Owing to their capacity for self-renewal and pluripotency, stem cells possess untold potential for revolutionizing the field of regenerative medicine through the development of novel therapeutic strategies for treating cancer, diabetes, cardiovascula
Autor:
Frederic Depreux, Andrew K. Groves, Aarohi Thakkar, William T. Choi, Aleksandar Bajić, Neil Segil, Mirjana Maletic-Savatic, Fatih Semerci, Juan Manuel Encinas
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Hippocampal neural stem cells (NSCs) integrate inputs from multiple sources to balance quiescence and activation. Notch signaling plays a key role during this process. Here, we report that Lunatic fringe (Lfng), a key modifier of the Notch receptor,
Autor:
Mirjana Maletic-Savatic, Andrew K. Groves, William T. Choi, Aarohi Thakkar, Aleksandar Bajić, Neil Segil, Juan Manuel Encinas, Fatih Semerci, Frederic Depreux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b7c0449beffe02c03b4c1c1c47fc20
https://doi.org/10.7554/elife.24660.016
https://doi.org/10.7554/elife.24660.016
Autor:
Marina Vannucci, Mirjana Maletic-Savatic, Christine B. Peterson, Lihua Ma, Cemal Karakas, William T. Choi
Publikováno v:
Statistics and Its Interface. 6:547-558
Metabolic processes are essential for cellular function and survival. We are interested in inferring a metabolic network in activated microglia, a major neuroimmune cell in the brain responsible for the neuroinflammation associated with neurological
Autor:
Matthew R. Folsom, Rizwan C. Naeem, Mohammed F. Azim, Rolf Marschalek, William T. Choi, Dean A. Lee, Nikolai A. Timchenko, Claus Meyer, Eric Kowarz
Publikováno v:
Cancer Genetics and Cytogenetics. 177:108-114
Translocations involving the mixed-lineage leukemia gene (MLL) confer a poor prognosis in acute leukemias. In t(1;11)(q21;q23), MLL is fused reciprocally with AF1q. Here we describe a t(1;11)(q21;q23) with a secondary event involving insertion of the
Autor:
Dhruv Pant, Jingchun Sun, Ying Wooi Wan, Lawrence A. Donehower, Zhandong Liu, Kaifang Pang, William T. Choi
Publikováno v:
Bioinformatics (Oxford, England). 30(10)
Motivation: Combinatorial therapies play increasingly important roles in combating complex diseases. Owing to the huge cost associated with experimental methods in identifying optimal drug combinations, computational approaches can provide a guide to