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pro vyhledávání: '"William T. Budd"'
Dual Action of miR-125b As a Tumor Suppressor and OncomiR-22 Promotes Prostate Cancer Tumorigenesis.
Autor:
William T Budd, Sarah J Seashols-Williams, Gene C Clark, Danielle Weaver, Valerie Calvert, Emanuel Petricoin, Ema A Dragoescu, Katherine O'Hanlon, Zendra E Zehner
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142373 (2015)
MicroRNAs (miRs) are a novel class of small RNA molecules, the dysregulation of which can contribute to cancer. A combinatorial approach was used to identify miRs that promote prostate cancer progression in a unique set of prostate cancer cell lines,
Externí odkaz:
https://doaj.org/article/93ff8048340f42859bb0c4201302ee38
Publikováno v:
Journal of Medical Microbiology. 65:377-386
Clinical management of bacterial vaginosis (BV) is difficult owing to inaccurate diagnostic tests, limited drug choices, and a high rate of recurrence. To our knowledge, there has not been a previous study of antimicrobial resistance (AMR) genes in c
Publikováno v:
Journal of Women's Health Care. 5
There is an unacceptably high recurrence rate for bacterial vaginosis and vaginitis owing to multiple causes, including misdiagnosis and empirical under-treatment and over-treatment. A diagnostic test that provided complete knowledge of the vaginal m
Publikováno v:
MOJ Cell Science & Report. 2
Molecular-based Phylogenetic analyses, including the newly-completed Human Microbiomes Project and other next-generation sequencing (NGS) studies have revealed the complexity of the vaginal micro biome in health and disease. The healthy vagina tends
Autor:
Katherine O’Hanlon, Zendra E. Zehner, Gene C. Clark, Valerie S. Calvert, William T. Budd, Danielle E. Weaver, Ema Dragoescu, Emanuel F. Petricoin, Sarah J. Seashols-Williams
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142373 (2015)
PLoS ONE
PLoS ONE
MicroRNAs (miRs) are a novel class of small RNA molecules, the dysregulation of which can contribute to cancer. A combinatorial approach was used to identify miRs that promote prostate cancer progression in a unique set of prostate cancer cell lines,
Autor:
William T. Budd, Zendra E. Zehner, Gene C. Clark, R Daniel, Sarah J. Seashols-Williams, Qianni Wu, Ema Dragoescu
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159601 (2016)
PLoS ONE
PLoS ONE
Identification of dysregulated microRNAs (miRNAs) in prostate cancer is critical not only for diagnosis, but also differentiation between the aggressive and indolent forms of the disease. miR-9 was identified as an oncomiR through both miRNA panel RT
Autor:
William T. Budd, Greg Meyers, Jeri R. Dilts, Katherine O', N.A. Hanlon, John R. Woody, David G. Bostwick, John R. Drury, Thomas Reynolds
Publikováno v:
International Journal of Computational Biology and Drug Design. 9:54
85% of medications prescribed are metabolised by a CYP450 superfamily member. This family contains SNPs linked to medication response. 30,000 participants were evaluated to determine potential differences in ethnic distributions of nucleotide polymor
Publikováno v:
Clinicalexperimental metastasis. 26(8)
MicroRNAs (miRs) are a novel class of RNAs with important roles in regulating gene expression. To identify miRs controlling prostate tumor progression, we utilized unique human prostate sublines derived from the parental P69 cell line, which differ i
Publikováno v:
BMC Systems Biology
Background Despite the lack of agreement on their exact roles, it is known that miRNAs contribute to cancer progression. Many studies utilize methods to detect differential regulation of miRNA expression. It is prohibitively expensive to examine all
Autor:
Emanuel F. Petricoin, Valerie Calvert, Danielle E. Weaver, Zendra E. Zehner, William T. Budd, Joy L. Ware
Publikováno v:
Cancer Research. 72:B54-B54
MicroRNAs (miRs) are small molecules that post-transcriptionally regulate expression of target mRNAs and are thought to play a major role in prostate cancer (CaP) tumorigenesis. We compared miR expression in a progressive prostate cancer cell model c