Zobrazeno 1 - 8
of 8
pro vyhledávání: '"William T Wickner"'
Autor:
Hongki Song, William T Wickner
Publikováno v:
eLife, Vol 10 (2021)
Yeast vacuolar membrane fusion has been reconstituted with R, Qa, Qb, and Qc-family SNAREs, Sec17/αSNAP, Sec18/NSF, and the hexameric HOPS complex. HOPS tethers membranes and catalyzes SNARE assembly into RQaQbQc trans-complexes which zipper through
Externí odkaz:
https://doaj.org/article/76c2c7b3397643d08d5dc1cdb337dee3
Publikováno v:
eLife, Vol 10 (2021)
Membrane fusion requires R-, Qa-, Qb-, and Qc-family SNAREs that zipper into RQaQbQc coiled coils, driven by the sequestration of apolar amino acids. Zippering has been thought to provide all the force driving fusion. Sec17/αSNAP can form an oligome
Externí odkaz:
https://doaj.org/article/9fa38d72a36e451c9a5603e6f551242c
Publikováno v:
eLife, Vol 9 (2020)
Yeast vacuole fusion requires R-SNARE, Q-SNAREs, and HOPS. A HOPS SM-family subunit binds the R- and Qa-SNAREs. We now report that HOPS binds each of the four SNAREs. HOPS catalyzes fusion when the Q-SNAREs are not pre-assembled, ushering them into a
Externí odkaz:
https://doaj.org/article/96ca243ac1224bc9b3276c51a02beeec
Publikováno v:
eLife, Vol 4 (2015)
Externí odkaz:
https://doaj.org/article/23cf9930ac914536b1dc17719f692ca2
Autor:
Michael Zick, William T Wickner
Publikováno v:
eLife, Vol 3 (2014)
Past experiments with reconstituted proteoliposomes, employing assays that infer membrane fusion from fluorescent lipid dequenching, have suggested that vacuolar SNAREs alone suffice to catalyze membrane fusion in vitro. While we could replicate thes
Externí odkaz:
https://doaj.org/article/c647d09b6c2b414798d5ab87bf987221
Publikováno v:
eLife, Vol 3 (2014)
Like other intracellular fusion events, the homotypic fusion of yeast vacuoles requires a Rab GTPase, a large Rab effector complex, SNARE proteins which can form a 4-helical bundle, and the SNARE disassembly chaperones Sec17p and Sec18p. In addition
Externí odkaz:
https://doaj.org/article/5b216bf6b34f472fbd5bd1d01bf42885
Publikováno v:
eLife
Yeast vacuole fusion requires R-SNARE, Q-SNAREs, and HOPS. A HOPS SM-family subunit binds the R- and Qa-SNAREs. We now report that HOPS binds each of the four SNAREs. HOPS catalyzes fusion when the Q-SNAREs are not pre-assembled, ushering them into a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69f938f69c58559496b0a7436ed6c3e5
https://pubmed.ncbi.nlm.nih.gov/31961324
https://pubmed.ncbi.nlm.nih.gov/31961324
