Zobrazeno 1 - 10
of 12
pro vyhledávání: '"William T Ireland"'
Autor:
William T Ireland, Suzannah M Beeler, Emanuel Flores-Bautista, Nicholas S McCarty, Tom Röschinger, Nathan M Belliveau, Michael J Sweredoski, Annie Moradian, Justin B Kinney, Rob Phillips
Publikováno v:
eLife, Vol 9 (2020)
Advances in DNA sequencing have revolutionized our ability to read genomes. However, even in the most well-studied of organisms, the bacterium Escherichia coli, for ≈65% of promoters we remain ignorant of their regulation. Until we crack this regul
Externí odkaz:
https://doaj.org/article/a102a55ccecf4145acbb0d068fc98190
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 2, p e1006226 (2019)
Despite the central importance of transcriptional regulation in biology, it has proven difficult to determine the regulatory mechanisms of individual genes, let alone entire gene networks. It is particularly difficult to decipher the biophysical mech
Externí odkaz:
https://doaj.org/article/e8e83fd9d62641d9bc9b9856d5a71195
Autor:
Ammar Tareen, Mahdi Kooshkbaghi, Anna Posfai, William T. Ireland, David M. McCandlish, Justin B. Kinney
Publikováno v:
Genome Biology. 23
Multiplex assays of variant effect (MAVEs), which include massively parallel reporter assays (MPRAs) and deep mutational scanning (DMS) experiments, are being rapidly adopted in many areas of biology. However, inferring quantitative models of genotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a92ae08aa3dc19f6dc158c7b2db7f6
https://doi.org/10.1186/s13059-022-02661-7
https://doi.org/10.1186/s13059-022-02661-7
Autor:
Nicholas S. McCarty, Emanuel Flores-Bautista, Justin B. Kinney, Tom Röschinger, Suzannah M. Beeler, William T. Ireland, Nathan M. Belliveau, Annie Moradian, Rob Phillips, Michael J. Sweredoski
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Advances in DNA sequencing have revolutionized our ability to read genomes. However, even in the most well-studied of organisms, the bacteriumEscherichia coli, for ≈65% of promoters we remain ignorant of their regulation. Until we crack this regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c073c294343ac9f5a3f69c97732ce4
http://europepmc.org/articles/PMC7567609
http://europepmc.org/articles/PMC7567609
Autor:
William T Ireland, Suzannah M Beeler, Emanuel Flores-Bautista, Nicholas S McCarty, Tom Röschinger, Nathan M Belliveau, Michael J Sweredoski, Annie Moradian, Justin B Kinney, Rob Phillips
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c32baa6bf429e153560e881aa890639
https://doi.org/10.7554/elife.55308.sa2
https://doi.org/10.7554/elife.55308.sa2
Autor:
Ammar Tareen, Bruce Stillman, Huilin Li, Christian Speck, William T. Ireland, Yi-Jun Sheu, Yixin Hu, Leemor Joshua-Tor, Justin B. Kinney
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
DNA replication in eukaryotic cells initiates from replication origins that bind the Origin Recognition Complex (ORC). Origin establishment requires well-defined DNA sequence motifs in Saccharomyces cerevisiae and some other budding yeasts, but most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a93f3394324e2d60f66a92c50013ed5
https://pubmed.ncbi.nlm.nih.gov/33056978
https://pubmed.ncbi.nlm.nih.gov/33056978
Autor:
Annie Moradian, William T. Ireland, Rob Phillips, Michael J. Sweredoski, Justin B. Kinney, Suzannah M. Beeler, Emanuel Flores-Bautista, Nathan M. Belliveau
Advances in DNA sequencing have revolutionized our ability to read genomes. However, even in the most well-studied of organisms, the bacteriumEscherichia coli, for ≈ 65% of the promoters we remain completely ignorant of their regulation. Until we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a77755b8600ec7dac235f06e8ba0fb6
https://doi.org/10.1101/2020.01.18.910323
https://doi.org/10.1101/2020.01.18.910323
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 15, Iss 2, p e1006226 (2019)
PLoS Computational Biology, Vol 15, Iss 2, p e1006226 (2019)
Despite the central importance of transcriptional regulation in biology, it has proven difficult to determine the regulatory mechanisms of individual genes, let alone entire gene networks. It is particularly difficult to decipher the biophysical mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051c26401f9348dcc5dd8e7a5449e4c6
https://pubmed.ncbi.nlm.nih.gov/30716072
https://pubmed.ncbi.nlm.nih.gov/30716072
Autor:
Rob Phillips, Michael J. Sweredoski, William T. Ireland, Sonja Hess, Justin B. Kinney, Daniel Jones, Nathan M. Belliveau, Annie Moradian, Stephanie L. Barnes
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(21)
Gene regulation is one of the most ubiquitous processes in biology. However, while the catalog of bacterial genomes continues to expand rapidly, we remain ignorant about how almost all of the genes in these genomes are regulated. At present, characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1e9f2422c06973ddfaa6bb4cb9df4b
https://pubmed.ncbi.nlm.nih.gov/29728462
https://pubmed.ncbi.nlm.nih.gov/29728462
Autor:
Sonja Hess, Stephanie L. Barnes, Nathan M. Belliveau, Rob Phillips, Annie Moradian, Justin B. Kinney, Michael J. Sweredoski, Daniel Jones, William T. Ireland
Gene regulation is one of the most ubiquitous processes in biology. But while the catalog of bacterial genomes continues to expand rapidly, we remain ignorant about how almost all of the genes in these genomes are regulated. At present, characterizin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2684eb8c6d75feb8df00af8ca32848
https://doi.org/10.1101/239335
https://doi.org/10.1101/239335