Zobrazeno 1 - 10
of 160
pro vyhledávání: '"William T Hu"'
Autor:
Caitlin D French, Rodney E Willoughby, Amy Pan, Susan J Wong, John F Foley, L Joseph Wheat, Josefina Fernandez, Rafael Encarnacion, Joanne M Ondrush, Naaz Fatteh, Andres Paez, Dan David, Waleed Javaid, Ioana G Amzuta, Anne M Neilan, Gregory K Robbins, Andrew M Brunner, William T Hu, Darya O Mishchuk, Carolyn M Slupsky
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0007045 (2018)
BACKGROUND:Myriad infectious and noninfectious causes of encephalomyelitis (EM) have similar clinical manifestations, presenting serious challenges to diagnosis and treatment. Metabolomics of cerebrospinal fluid (CSF) was explored as a method of diff
Externí odkaz:
https://doaj.org/article/3aa1082067824612992ccdc101c68946
Autor:
William T Hu, Matthew Shelnutt, Ashley Wilson, Nicole Yarab, Crystal Kelly, Murray Grossman, David J Libon, Jaffar Khan, James J Lah, Allan I Levey, Jonathan Glass
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57584 (2013)
It is difficult to longitudinally characterize cognitive impairment in amyotrophic lateral sclerosis (ALS) due to motor deficits, and existing instruments aren't comparable with assessments in other dementias.The ALS Brief Cognitive Assessment (ALS-B
Externí odkaz:
https://doaj.org/article/c9245e48d11f430abc56eeb9c2728539
Autor:
Karthik J Kota, Alice Dawson, Julia Papas, Victor Sotelo, Guibin Su, Mei‐Ling Li, Woowon Lee, Jaunis Estervil, Melissa Marquez, Shromona Sarkar, Lisa Lanza Lopez, William T. Hu
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION South Asian (SA) and East Asian (EA) older adults represent the fastest‐growing racial/ethnic groups of Americans at risk for dementia. While recruiting older SA adults into a brain health study, we encountered unexpected hesi
Externí odkaz:
https://doaj.org/article/8ee03af7f9e347b8afefc89fb7c69875
Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease
Autor:
William T. Hu, Tugba Ozturk, Alexander Kollhoff, Whitney Wharton, J. Christina Howell, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Neuroinflammation is observed in Alzheimer’s disease. Here the authors show that 15 proteins related to inflammation found in CSF can potentially be used as a prognostic biomarker.
Externí odkaz:
https://doaj.org/article/2a5992a3df1849a68aa9346666827c8c
Autor:
Anthony W.S. Chan, In Ki Cho, Chun-Xia Li, Xiaodong Zhang, Sudeep Patel, Rebecca Rusnak, Jessica Raper, Jocelyne Bachevalier, Sean P. Moran, Tim Chi, Katherine H. Cannon, Carissa E. Hunter, Ryan C. Martin, Hailian Xiao, Shang-Hsun Yang, Sanjeev Gumber, James G. Herndon, Rebecca F. Rosen, William T. Hu, James J. Lah, Allan I. Levey, Yoland Smith, Lary C. Walker
Publikováno v:
Aging Brain, Vol 2, Iss , Pp 100044- (2022)
With the ultimate goal of developing a more representative animal model of Alzheimer's disease (AD), two female amyloid-β-(Aβ) precursor protein-transgenic (APPtg) rhesus monkeys were generated by lentiviral transduction of the APP gene into rhesus
Externí odkaz:
https://doaj.org/article/e37b891206f5479e91e23e9f894ea295
Autor:
Marta del Campo, Carel F. W. Peeters, Erik C. B. Johnson, Lisa Vermunt, Yanaika S. Hok-A-Hin, Mirrelijn van Nee, Alice Chen-Plotkin, David J. Irwin, William T. Hu, James J. Lah, Nicholas T. Seyfried, Eric B. Dammer, Gonzalo Herradon, Lieke H. Meeter, John van Swieten, Daniel Alcolea, Alberto Lleó, Allan I. Levey, Afina W. Lemstra, Yolande A. L. Pijnenburg, Pieter J. Visser, Betty M. Tijms, Wiesje M. van der Flier, Charlotte E. Teunissen
Publikováno v:
Nature aging, 2(11), 1040-+. Nature Publishing Group
del Campo, M, Peeters, C F W, Johnson, E C B, Vermunt, L, Hok-A-Hin, Y S, van Nee, M, Chen-Plotkin, A, Irwin, D J, Hu, W T, Lah, J J, Seyfried, N T, Dammer, E B, Herradon, G, Meeter, L H, van Swieten, J, Alcolea, D, Lleó, A, Levey, A I, Lemstra, A W, Pijnenburg, Y A L, Visser, P J, Tijms, B M, van der Flier, W M & Teunissen, C E 2022, ' CSF proteome profiling across the Alzheimer’s disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels ', Nature Aging, vol. 2, no. 11, pp. 1040-1053 . https://doi.org/10.1038/s43587-022-00300-1
Nature Aging, 2(11), 1040-1053
Nature Aging, 2(11), 1040-1053. Springer
Nature Aging 2 (2022) 11
del Campo, M, Peeters, C F W, Johnson, E C B, Vermunt, L, Hok-A-Hin, Y S, van Nee, M, Chen-Plotkin, A, Irwin, D J, Hu, W T, Lah, J J, Seyfried, N T, Dammer, E B, Herradon, G, Meeter, L H, van Swieten, J, Alcolea, D, Lleó, A, Levey, A I, Lemstra, A W, Pijnenburg, Y A L, Visser, P J, Tijms, B M, van der Flier, W M & Teunissen, C E 2022, ' CSF proteome profiling across the Alzheimer’s disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels ', Nature Aging, vol. 2, no. 11, pp. 1040-1053 . https://doi.org/10.1038/s43587-022-00300-1
Nature Aging, 2(11), 1040-1053
Nature Aging, 2(11), 1040-1053. Springer
Nature Aging 2 (2022) 11
Development of disease-modifying therapies against Alzheimer's disease (AD) requires biomarkers reflecting the diverse pathological pathways specific for AD. We measured 665 proteins in 797 cerebrospinal fluid (CSF) samples from patients with mild co
Autor:
Umesh Gangishetti, J. Christina Howell, Richard J. Perrin, Natalia Louneva, Kelly D. Watts, Alexander Kollhoff, Murray Grossman, David A. Wolk, Leslie M. Shaw, John C. Morris, John Q. Trojanowski, Anne M. Fagan, Steven E. Arnold, William T. Hu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by neuropathologic changes involving beta-amyloid (Aβ), tau, neuronal loss, and other associated biological events. While levels of cerebrospinal fl
Externí odkaz:
https://doaj.org/article/8a4b4784e2dd4852bbf5da6fc02770db
Autor:
Jennifer C. Howell, Kelly D. Watts, Monica W. Parker, Junjie Wu, Alexander Kollhoff, Thomas S. Wingo, Cornelya D. Dorbin, Deqiang Qiu, William T. Hu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-10 (2017)
Abstract Background African Americans have been reported to have a higher prevalence of Alzheimer’s disease (AD) than Caucasians, but etiology-specific AD biomarkers have not been systematically analyzed in older African Americans. Coexisting cereb
Externí odkaz:
https://doaj.org/article/4cc6710c2b3e4de289fd47f8d9a2fd33
Autor:
Courtney M. Kloske, Christopher J. Barnum, Andre F. Batista, Elizabeth M. Bradshaw, Adam M. Brickman, Guojun Bu, Jessica Dennison, Mary D. Gearon, Alison M. Goate, Christian Haass, Michael T. Heneka, William T. Hu, Lenique K. L. Huggins, Nahdia S. Jones, Radosveta Koldamova, Cynthia A. Lemere, Shane A. Liddelow, Edoardo Marcora, Samuel E. Marsh, Henrietta M. Nielsen, Kellen K. Petersen, Melissa Petersen, Stefanie D. Piña‐Escudero, Wei Qiao Qiu, Yakeel T. Quiroz, Eric Reiman, Claire Sexton, Malú Gámez Tansey, Julia TCW, Charlotte E. Teunissen, Betty M. Tijms, Rik van der Kant, Rebecca Wallings, Stacie C. Weninger, Whitney Wharton, Donna M. Wilcock, Tyler James Wishard, Susan L Worley, Henrik Zetterberg, Maria C. Carrillo
Publikováno v:
Kloske, C M, Barnum, C J, Batista, A F, Bradshaw, E M, Brickman, A M, Bu, G, Dennison, J, Gearon, M D, Goate, A M, Haass, C, Heneka, M T, Hu, W T, Huggins, L K L, Jones, N S, Koldamova, R, Lemere, C A, Liddelow, S A, Marcora, E, Marsh, S E, Nielsen, H M, Petersen, K K, Petersen, M, Piña-Escudero, S D, Qiu, W Q, Quiroz, Y T, Reiman, E, Sexton, C, Tansey, M G M, Tcw, J, Teunissen, C E, Tijms, B M, van der Kant, R, Wallings, R, Weninger, S C, Wharton, W, Wilcock, D M, Wishard, T J, Worley, S L, Zetterberg, H & Carrillo, M C 2023, ' APOE and immunity : Research highlights ', Alzheimer's and Dementia, vol. 19, no. 6, pp. 2677-2696 . https://doi.org/10.1002/alz.13020
Alzheimer's and dementia 19(6), 2677-2696 (2023). doi:10.1002/alz.13020
Kloske, C M, Barnum, C J, Batista, A F, Bradshaw, E M, Brickman, A M, Bu, G, Dennison, J, Gearon, M D, Goate, A M, Haass, C, Heneka, M T, Hu, W T, Huggins, L K L, Jones, N S, Koldamova, R, Lemere, C A, Liddelow, S A, Marcora, E, Marsh, S E, Nielsen, H M, Petersen, K K, Petersen, M, Piña-Escudero, S D, Qiu, W Q, Quiroz, Y T, Reiman, E, Sexton, C, Tansey, M G, Tcw, J, Teunissen, C E, Tijms, B M, van der Kant, R, Wallings, R, Weninger, S C, Wharton, W, Wilcock, D M, Wishard, T J, Worley, S L, Zetterberg, H & Carrillo, M C 2023, ' APOE and immunity: Research highlights ', Alzheimer's and Dementia, vol. 19, no. 6, pp. 2677-2696 . https://doi.org/10.1002/alz.13020
Alzheimer's and dementia 19(6), 2677-2696 (2023). doi:10.1002/alz.13020
Kloske, C M, Barnum, C J, Batista, A F, Bradshaw, E M, Brickman, A M, Bu, G, Dennison, J, Gearon, M D, Goate, A M, Haass, C, Heneka, M T, Hu, W T, Huggins, L K L, Jones, N S, Koldamova, R, Lemere, C A, Liddelow, S A, Marcora, E, Marsh, S E, Nielsen, H M, Petersen, K K, Petersen, M, Piña-Escudero, S D, Qiu, W Q, Quiroz, Y T, Reiman, E, Sexton, C, Tansey, M G, Tcw, J, Teunissen, C E, Tijms, B M, van der Kant, R, Wallings, R, Weninger, S C, Wharton, W, Wilcock, D M, Wishard, T J, Worley, S L, Zetterberg, H & Carrillo, M C 2023, ' APOE and immunity: Research highlights ', Alzheimer's and Dementia, vol. 19, no. 6, pp. 2677-2696 . https://doi.org/10.1002/alz.13020
INTRODUCTION: At the Alzheimer's Association's APOE and Immunity virtual conference, held in October 2021, leading neuroscience experts shared recent research advances on and inspiring insights into the various roles that both the apolipoprotein E ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d9ff92093ab0b6d772041ff569c18f
https://research.vumc.nl/en/publications/823b40ac-c075-4456-8a2d-bdf139906d29
https://research.vumc.nl/en/publications/823b40ac-c075-4456-8a2d-bdf139906d29
Autor:
Karthik Kota, Alice Dawson, Julia Papas, Victor Sotelo, Guibin Su, Mei-Ling Li, Woowon Lee, Jaunis Estervil, Melissa Marquez, Shromona Sarkar, Lisa Lanza Lopez, William T. Hu
Publikováno v:
medRxiv
INTRODUCTIONSouth Asian (SA) and East Asian (EA) older adults represent the fastest growing group of Americans at risk for dementia, but their participation in aging and dementia research has been limited. While recruiting healthy SA older adults int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488f95dc19cdf23135429c81efcfef70
https://doi.org/10.1101/2023.04.17.23288629
https://doi.org/10.1101/2023.04.17.23288629