Zobrazeno 1 - 10
of 17
pro vyhledávání: '"William T Horne"'
Autor:
Miguel Pinilla-Vera, Zeyu Xiong, Yutong Zhao, Jing Zhao, Michael P Donahoe, Suchitra Barge, William T Horne, Jay K Kolls, Bryan J McVerry, Anastasiya Birukova, Robert M Tighe, W Michael Foster, John Hollingsworth, Anuradha Ray, Rama Mallampalli, Prabir Ray, Janet S Lee
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159329 (2016)
Despite recent advances in understanding macrophage activation, little is known regarding how human alveolar macrophages in health calibrate its transcriptional response to canonical TLR4 activation. In this study, we examined the full spectrum of LP
Externí odkaz:
https://doaj.org/article/ef02527a842b489e8b337410d2604e08
Autor:
Josep Bassaganya-Riera, Maria Gloria Dominguez-Bello, Barbara Kronsteiner, Adria Carbo, Pinyi Lu, Monica Viladomiu, Mireia Pedragosa, Xiaoying Zhang, Bruno W Sobral, Shrinivasrao P Mane, Saroj K Mohapatra, William T Horne, Amir J Guri, Michael Groeschl, Gabriela Lopez-Velasco, Raquel Hontecillas
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50069 (2012)
There is an inverse secular trend between the incidence of obesity and gastric colonization with Helicobacter pylori, a bacterium that can affect the secretion of gastric hormones that relate to energy homeostasis. H. pylori strains that carry the ca
Externí odkaz:
https://doaj.org/article/50f9baf8dd0c4e83a2bf6026b3bd8b53
Autor:
Pinyi Lu, Raquel Hontecillas, William T Horne, Adria Carbo, Monica Viladomiu, Mireia Pedragosa, David R Bevan, Stephanie N Lewis, Josep Bassaganya-Riera
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34643 (2012)
Lanthionine synthetase component C-like protein 2 (LANCL2) is a member of the eukaryotic lanthionine synthetase component C-Like protein family involved in signal transduction and insulin sensitization. Recently, LANCL2 is a target for the binding an
Externí odkaz:
https://doaj.org/article/2a26908d01ad48eb952877298a784aa9
Autor:
Saroj K Mohapatra, Amir J Guri, Montse Climent, Cristina Vives, Adria Carbo, William T Horne, Raquel Hontecillas, Josep Bassaganya-Riera
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10215 (2010)
BACKGROUND: Peroxisome proliferator-activated receptors are nuclear receptors highly expressed in intestinal epithelial cells (IEC) and immune cells within the gut mucosa and are implicated in modulating inflammation and immune responses. The objecti
Externí odkaz:
https://doaj.org/article/3484562b134e4114b166de3da3c2df3d
Autor:
John F. Alcorn, Raghunandan Avula, Anish B. Chakka, William E. Schwarzmann, Mary Patricia Nowalk, Chyongchiou Jeng Lin, Marianna A. Ortiz, William T. Horne, Uma R. Chandran, Jennifer P. Nagg, Richard K. Zimmerman, Kelly S. Cole, Krissy K. Moehling, Judith M. Martin
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 8, Pp 1782-1790 (2020)
The human immune response to inactivated influenza vaccine is dynamic and impacted by age and preexisting immunity. Our goal was to identify postvaccination transcriptomic changes in peripheral blood mononuclear cells from children. Blood samples wer
Externí odkaz:
https://doaj.org/article/79583ce0bc624b1bbc86e1fbb43f56cc
Autor:
Taylor Eddens, Waleed Elsegeiny, David Ricks, Meagan Goodwin, William T. Horne, Mingquan Zheng, Jay K. Kolls
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
ABSTRACT Pneumocystis pneumonia is the most common serious opportunistic infection in patients with HIV/AIDS. Furthermore, Pneumocystis pneumonia is a feared complication of the immunosuppressive drug regimens used to treat autoimmunity, malignancy,
Externí odkaz:
https://doaj.org/article/7875506580b74fc792633149e3c8237d
Autor:
Josep Bassaganya-Riera, William T. Horne, Raquel Hontecillas, Adria Carbo, M H Koch, William E. Barbeau
Publikováno v:
Clinical and Experimental Immunology. 175:167-171
Summary Some type 1 diabetes (T1D) patients have been reported to exhibit T cell reactivity to wheat gluten. We tested the hypothesis that this T cell reactivity could be abolished by using prolyl-endopeptidase (PEP), an enzyme that cleaves peptide b
Autor:
William T. Horne, Sandra Genis, Binu Velayudhan, Raquel Hontecillas, Josep Bassaganya-Riera, Paul C. Roberts, Adria Carbo, Cristina Vives
Publikováno v:
The Journal of Nutritional Biochemistry. 24:1019-1027
The anti-inflammatory phytohormone abscisic acid (ABA) modulates immune and inflammatory responses in mouse models of colitis and obesity. ABA has been identified as a ligand of lanthionine synthetase C-like 2, a novel therapeutic target upstream of
Autor:
Raquel Hontecillas, William T. Horne, Josep Bassaganya-Riera, Mikki Sandridge, Hans H Herfarth, Richard S. Bloomfeld, Kim L. Isaacs
Publikováno v:
Clinical Nutrition. 31:721-727
summary Background & aims: Conjugated linoleic acid (CLA) has demonstrated efficacy as an immune modulator and anti-inflammatory compound in mouse and pig models of colitis. We investigated the immunoregulatory efficacy of CLA in patients with mild t
Autor:
William T. Horne, Thomas J. Inzana, Frank St. Michael, Lisa M. Willis, Josep Bassaganya-Riera, Michael D. Howard, Andrew D. Cox, Raquel Hontecillas, Warren W. Wakarchuk, Eva Lorenz
Publikováno v:
Veterinary Microbiology. 153:163-172
Histophilus somni is an etiologic agent of bovine respiratory and systemic diseases. Most pathogenic strains of H. somni that have been tested (36 of 42) are able to utilize N -acetyl-5-neuraminic acid (Neu5Ac) to sialylate their lipooligosaccharide