Zobrazeno 1 - 10
of 10
pro vyhledávání: '"William Swaney"'
Autor:
Sant P. Chawla, Steven Wong, Doris Quon, Ania Moradkhani, Victoria S. Chua, Don A. Brigham, Rebecca A Reed, William Swaney, Frederick L. Hall, Erlinda M. Gordon
Publikováno v:
Frontiers in Molecular Medicine, Vol 2 (2022)
Background: Innovative treatments are urgently needed for metastatic cancer. DeltaRex-G, a tumor-targeted retrovector encoding a dominant-negative/cytocidal cyclin G1 (CCNG1 gene) inhibitor construct—has been tested in over 280 cancer patients worl
Externí odkaz:
https://doaj.org/article/ec84daaadc184d128fc1926eced547a0
Autor:
William Swaney, Michael Green
Publikováno v:
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution.
The environment plays an important role in an individual's development during early life, however, parents may also influence offspring development through so called "parental effects." We examined the effects of environmental enrichment in zebrafish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a39a9f430e821970fb53ec57c036da
https://doi.org/10.1002/jez.b.23184
https://doi.org/10.1002/jez.b.23184
Autor:
Kristen Herzegh, William Swaney, H. Trent Spencer, Eric Day, Anindya Dasgupta, Christopher B. Doering
Publikováno v:
Current Stem Cell Reports
Purpose of review The promise of cell and gene therapy (CGT) products for a multitude of diseases has revitalized investigators to advance novel CGT product candidates to first-in-human trials by pursuing the investigational new drug (IND) mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d6d391e1b9197bb58ecbba27a60d7a
https://pubmed.ncbi.nlm.nih.gov/34608428
https://pubmed.ncbi.nlm.nih.gov/34608428
Autor:
Erlinda Maria Gordon, Victoria S. Chua-Alcala, Simranjit Sekhon, Noufil Adnan, Steve Wong, Doris V. Quon, Ania Moradkhani, Noah Federman, Don Arlen Brigham, Rebecca Reed, William Swaney, Frederick L. Hall, Sant P. Chawla
Publikováno v:
Journal of Clinical Oncology. 40:e15048-e15048
e15048 Background: Defects in cell cycle control are fundamental oncogenic drivers and targeting deregulated cell cycling is under intensive study. Cell cycle cyclin G1 (CCNG1) inhibitor therapy, exemplified by DeltaRex-G, a tumor-targeted retro vect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a05666880aff80379b86bd713442889
https://doi.org/10.1200/jco.2022.40.16_suppl.e15048
https://doi.org/10.1200/jco.2022.40.16_suppl.e15048
Autor:
Anindya, Dasgupta, Stuart, Tinch, Kathleen, Szczur, Rebecca, Ernst, Nathaniel, Shryock, Courtney, Kaylor, Kendall, Lewis, Eric, Day, Timmy, Truong, William, Swaney
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2086
In clinical gene transfer applications, lentiviral vectors (LV) have rapidly become the primary means to achieve permanent and stable expression of a gene of interest or alteration of gene expression in target cells. This status can be attributed pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47b25798a49027f8b192f01446c19656
https://pubmed.ncbi.nlm.nih.gov/31707666
https://pubmed.ncbi.nlm.nih.gov/31707666
Autor:
Kendall Lewis, William Swaney, Nathaniel Shryock, Stuart Tinch, Anindya Dasgupta, Rebecca Ernst, Timmy Truong, Courtney Kaylor, Kathleen Szczur, Eric Day
Publikováno v:
Methods in Molecular Biology ISBN: 9781071601457
In clinical gene transfer applications, lentiviral vectors (LV) have rapidly become the primary means to achieve permanent and stable expression of a gene of interest or alteration of gene expression in target cells. This status can be attributed pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8fdf03f034e2aa5114d04a71718a218
https://doi.org/10.1007/978-1-0716-0146-4_3
https://doi.org/10.1007/978-1-0716-0146-4_3
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1937
Lentiviral vectors have rapidly become a favorite tool for research and clinical gene transfer applications which seek to permanently introduce alterations in the genome. This status can be attributed primarily to their ability to transduce dividing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8cd07a4cc4091e252650fba11a9002b5
https://pubmed.ncbi.nlm.nih.gov/30706394
https://pubmed.ncbi.nlm.nih.gov/30706394
Publikováno v:
Methods in Molecular Biology ISBN: 9781493990641
Lentiviral vectors have rapidly become a favorite tool for research and clinical gene transfer applications which seek to permanently introduce alterations in the genome. This status can be attributed primarily to their ability to transduce dividing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af0eb9098c01765fc75e7fdd0eb21aa8
https://doi.org/10.1007/978-1-4939-9065-8_8
https://doi.org/10.1007/978-1-4939-9065-8_8
Autor:
Lilith Reeves, Jordan E Shields, Gabriela Denning, Christopher B. Doering, William Swaney, H. Trent Spencer, Punam Malik
Publikováno v:
Blood. 126:4421-4421
Hemophilia A is a monogenic bleeding disorder currently treated by lifelong infusions of factor VIII (fVIII). The development of gene-based treatments for hemophilia A has been hampered by several biological hurdles including the low level expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cfcf0ff29bf6707fa440bd4860387fa
https://doi.org/10.1182/blood.v126.23.4421.4421
https://doi.org/10.1182/blood.v126.23.4421.4421
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 449
We have developed protocols whereby a total of 30-90 x 10(6) hMSCs with an average viability greater than 90% can be produced in a single multilevel Cell Factory from a relatively small (1-3 mL) bone marrow aspirate in 14-20 d. It is possible to gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6aab2161b180c5b8a890c3d1f4a0d06
https://pubmed.ncbi.nlm.nih.gov/18370080
https://pubmed.ncbi.nlm.nih.gov/18370080