Zobrazeno 1 - 10
of 179
pro vyhledávání: '"William Stone"'
Publikováno v:
Oxygen, Vol 4, Iss 3, Pp 351-362 (2024)
Evidence suggests that COVID-19 infection increases the risk of type 1 (T1D) and type 2 diabetes (T2D). Diabetes, in turn, increases COVID-19 susceptibility and contributes to increased COVID-19 morbidity and mortality. Oxidative stress has emerged a
Externí odkaz:
https://doaj.org/article/29807caeee74496bb1d469c603b0859a
Autor:
Matthew Higgins, Mojca Kristan, Emma L. Collins, Louisa A. Messenger, Jamille G. Dombrowski, Leen N. Vanheer, Debbie Nolder, Christopher J. Drakeley, William Stone, Almahamoudou Mahamar, Teun Bousema, Michael Delves, Janvier Bandibabone, Sévérin N’Do, Chimanuka Bantuzeko, Bertin Zawadi, Thomas Walker, Colin J. Sutherland, Claudio R. F. Marinho, Mary M. Cameron, Taane G. Clark, Susana Campino
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Robust diagnostic tools and surveillance are crucial for malaria control and elimination efforts. Malaria caused by neglected Plasmodium parasites is often underestimated due to the lack of rapid diagnostic tools that can accurately detect t
Externí odkaz:
https://doaj.org/article/a62e65a32f43462287335f4c454f7c0a
Autor:
Leen N. Vanheer, Almahamoudou Mahamar, Emilia Manko, Sidi M. Niambele, Koualy Sanogo, Ahamadou Youssouf, Adama Dembele, Makonon Diallo, Seydina O. Maguiraga, Jody Phelan, Ashley Osborne, Anton Spadar, Merel J. Smit, Teun Bousema, Chris Drakeley, Taane G. Clark, William Stone, Alassane Dicko, Susana Campino
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Sequence analysis of Plasmodium falciparum parasites is informative in ensuring sustained success of malaria control programmes. Whole-genome sequencing technologies provide insights into the epidemiology and genome-wide variation of P. falc
Externí odkaz:
https://doaj.org/article/1b0a0aff8b5f4741830b1dd2c4d9313e
Autor:
William Stone, Chloe Strege, William Miller, Aron M Geurts, Michael Grzybowski, Megan Riddle, Christopher Lees, Cindy Eide, Douglas R Keene, Sara F Tufa, Davis Seelig, John McGrath, Jakub Tolar
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0302991 (2024)
Recessive dystrophic epidermolysis bullosa is a rare genodermatosis caused by a mutation of the Col7a1 gene. The Col7a1 gene codes for collagen type VII protein, a major component of anchoring fibrils. Mutations of the Col7a1 gene can cause aberrant
Externí odkaz:
https://doaj.org/article/26c85a29463242dcad126e3a75402d50
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 184 (2024)
Type 2 diabetes (T2D) is a major worldwide health crisis affecting about 6.2% of the world’s population. Alarmingly, about one in five children in the USA have prediabetes. Glutathione (GSH) and its precursors play a promising role in the preventio
Externí odkaz:
https://doaj.org/article/589c3b9ce8e044008e1849d3d1edd922
Autor:
María Florencia Pavan, Marina Bok, Rafael Betanzos San Juan, Juan Pablo Malito, Gisela Ariana Marcoppido, Diego Rafael Franco, Daniela Ayelen Militelo, Juan Manuel Schammas, Sara Elizabeth Bari, William Stone, Krisangel López, Danielle LaBrie Porier, John Anthony Muller, Albert Jonathan Auguste, Lijuan Yuan, Andrés Wigdorovitz, Viviana Gladys Parreño, Lorena Itat Ibañez
Publikováno v:
Viruses, Vol 16, Iss 2, p 185 (2024)
Since the beginning of the COVID-19 pandemic, there has been a significant need to develop antivirals and vaccines to combat the disease. In this work, we developed llama-derived nanobodies (Nbs) directed against the receptor binding domain (RBD) and
Externí odkaz:
https://doaj.org/article/5eba587ec99b43638a5876bf15935f93
Autor:
Carolyn M. Amir, Simon Kapler, Gil D. Hoftman, Leila Kushan, Jamie Zinberg, Kristin S. Cadenhead, Leda Kennedy, Barbara A. Cornblatt, Matcheri Keshavan, Daniel H. Mathalon, Diana O. Perkins, William Stone, Ming T. Tsuang, Elaine F. Walker, Scott W. Woods, Tyrone D. Cannon, Jean Addington, Carrie E. Bearden
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundElevated rates of alcohol, tobacco, and cannabis use are observed in both patients with psychotic disorders and individuals at clinical high risk for psychosis (CHR-P), and strong genetic associations exist between substance use disorders a
Externí odkaz:
https://doaj.org/article/8a9a5d57faa949ce9a94dd9e1750b6d4
Autor:
Abraham Nunes, William Stone, Raffaella Ardau, Anne Berghöfer, Alberto Bocchetta, Caterina Chillotti, Valeria Deiana, Franziska Degenhardt, Andreas J. Forstner, Julie S. Garnham, Eva Grof, Tomas Hajek, Mirko Manchia, Manuel Mattheisen, Francis McMahon, Bruno Müller-Oerlinghausen, Markus M. Nöthen, Marco Pinna, Claudia Pisanu, Claire O’Donovan, Marcella D. C. Rietschel, Guy Rouleau, Thomas Schulze, Giovanni Severino, Claire M. Slaney, Alessio Squassina, Aleksandra Suwalska, Gustavo Turecki, Rudolf Uher, Petr Zvolsky, Pablo Cervantes, Maria del Zompo, Paul Grof, Janusz Rybakowski, Leonardo Tondo, Thomas Trappenberg, Martin Alda
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Predicting lithium response (LiR) in bipolar disorder (BD) may inform treatment planning, but phenotypic heterogeneity complicates discovery of genomic markers. We hypothesized that patients with “exemplary phenotypes”—those whose clin
Externí odkaz:
https://doaj.org/article/148507cd1abd48b0b4092cfa43da61f1
Autor:
William Stone, Abraham Nunes, Kazufumi Akiyama, Nirmala Akula, Raffaella Ardau, Jean-Michel Aubry, Lena Backlund, Michael Bauer, Frank Bellivier, Pablo Cervantes, Hsi-Chung Chen, Caterina Chillotti, Cristiana Cruceanu, Alexandre Dayer, Franziska Degenhardt, Maria Del Zompo, Andreas J. Forstner, Mark Frye, Janice M. Fullerton, Maria Grigoroiu-Serbanescu, Paul Grof, Ryota Hashimoto, Liping Hou, Esther Jiménez, Tadafumi Kato, John Kelsoe, Sarah Kittel-Schneider, Po-Hsiu Kuo, Ichiro Kusumi, Catharina Lavebratt, Mirko Manchia, Lina Martinsson, Manuel Mattheisen, Francis J. McMahon, Vincent Millischer, Philip B. Mitchell, Markus M. Nöthen, Claire O’Donovan, Norio Ozaki, Claudia Pisanu, Andreas Reif, Marcella Rietschel, Guy Rouleau, Janusz Rybakowski, Martin Schalling, Peter R. Schofield, Thomas G. Schulze, Giovanni Severino, Alessio Squassina, Julia Veeh, Eduard Vieta, Thomas Trappenberg, Martin Alda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Predicting lithium response prior to treatment could both expedite therapy and avoid exposure to side effects. Since lithium responsiveness may be heritable, its predictability based on genomic data is of interest. We thus evaluate the degre
Externí odkaz:
https://doaj.org/article/3122c8062c9b4f39a9a4aa0e6220ae8c
Autor:
Christine Moore, Victoria E. Palau, Rashid Mahboob, Janet Lightner, William Stone, Koyamangalath Krishnan
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background α-tocopherol (AT) and γ-tocotrienol (GT3) are vitamin E isoforms considered to have potential chemopreventive properties. AT has been widely studied in vitro and in clinical trials with mixed results. The latest clinical study (
Externí odkaz:
https://doaj.org/article/e2ccc89cb6144ce2b0a56d2f501ff1cb