Zobrazeno 1 - 10
of 18
pro vyhledávání: '"William Schachterle"'
Autor:
William Schachterle, Chaitanya R. Badwe, Brisa Palikuqi, Balvir Kunar, Michael Ginsberg, Raphael Lis, Masataka Yokoyama, Olivier Elemento, Joseph M. Scandura, Shahin Rafii
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Endothelial cells (ECs) are promising strategies to treat vasculopathies but little is known about the factors that sustain EC identity and govern functional integration into vasculature after transplantation. Here the authors show that Ets factors a
Externí odkaz:
https://doaj.org/article/11bf9229b67e48d3aa00b6943deb460c
Autor:
Michael G. Poulos, Michael J.P. Crowley, Michael C. Gutkin, Pradeep Ramalingam, William Schachterle, Jean-Leon Thomas, Olivier Elemento, Jason M. Butler
Publikováno v:
Stem Cell Reports, Vol 5, Iss 5, Pp 881-894 (2015)
Hematopoietic stem cells (HSCs) inhabit distinct microenvironments within the adult bone marrow (BM), which govern the delicate balance between HSC quiescence, self-renewal, and differentiation. Previous reports have proposed that HSCs localize to th
Externí odkaz:
https://doaj.org/article/06c03862ec6a47019427c26a553e3d6c
Autor:
Joseph M. Scandura, Chaitanya R. Badwe, Balvir Kunar, Masataka Yokoyama, Michael Ginsberg, Brisa Palikuqi, Olivier Elemento, William Schachterle, Raphael Lis, Shahin Rafii
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
Transplanting vascular endothelial cells (ECs) to support metabolism and express regenerative paracrine factors is a strategy to treat vasculopathies and to promote tissue regeneration. However, transplantation strategies have been challenging to dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a21182cc8a0b518712105598dc2598
https://doaj.org/article/11bf9229b67e48d3aa00b6943deb460c
https://doaj.org/article/11bf9229b67e48d3aa00b6943deb460c
Publikováno v:
Nature Protocols. 10:1975-1985
Endothelial cells (ECs) have essential roles in organ development and regeneration, and therefore they could be used for regenerative therapies. However, generation of abundant functional endothelium from pluripotent stem cells has been difficult bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5743e1372fa1667dcd1843802a6d75e
https://doi.org/10.1038/nprot.2015.126
https://doi.org/10.1038/nprot.2015.126
Autor:
Jason M. Butler, Michael J. Crowley, William Schachterle, Michael C. Gutkin, Michael G. Poulos, Pradeep Ramalingam, Olivier Elemento, Jean-Leon Thomas
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Elsevier, 2015, 5 (5), pp.881-894. ⟨10.1016/j.stemcr.2015.08.018⟩
Stem Cell Reports, Vol 5, Iss 5, Pp 881-894 (2015)
Stem Cell Reports, 2015, 5 (5), pp.881-894. ⟨10.1016/j.stemcr.2015.08.018⟩
Stem Cell Reports, Elsevier, 2015, 5 (5), pp.881-894. ⟨10.1016/j.stemcr.2015.08.018⟩
Stem Cell Reports, Vol 5, Iss 5, Pp 881-894 (2015)
Stem Cell Reports, 2015, 5 (5), pp.881-894. ⟨10.1016/j.stemcr.2015.08.018⟩
Summary Hematopoietic stem cells (HSCs) inhabit distinct microenvironments within the adult bone marrow (BM), which govern the delicate balance between HSC quiescence, self-renewal, and differentiation. Previous reports have proposed that HSCs locali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfb2d977318da30e7ed664987607f3f
http://europepmc.org/articles/PMC4649106
http://europepmc.org/articles/PMC4649106
Autor:
Jenny Xiang, Olivier Elemento, Chaitanya R. Badwe, Jason M. Butler, Zev Rosenwaks, Charles C. Karrasch, Nancy A. Speck, Koji Shido, William Schachterle, Michael Ginsberg, Michael G. Poulos, Balvir Kunar, Raphael Lis, Arash Rafii Tabrizi, David Redmond, Joseph M. Scandura, José Gabriel Barcia Durán, Shahin Rafii
Developmental pathways that orchestrate the fleeting transition of endothelial cells into haematopoietic stem cells remain undefined. Here we demonstrate a tractable approach for fully reprogramming adult mouse endothelial cells to haematopoietic ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d662f8ea5f8d2727bb517ee1f680122d
https://europepmc.org/articles/PMC5794215/
https://europepmc.org/articles/PMC5794215/
Autor:
Brian L. Black, Anabel Rojas, Ian S. Harris, David J. McCulley, William Schachterle, Russell A. Norris, Kimberly Sauls, Tanvi Sinha, Eric J. Jaehnig, Ralston M. Barnes
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
Barnes, Ralston M. et al.
Congenital heart defects are the most common birth defects in humans, and those that affect the proper alignment of the outflow tracts and septation of the ventricles are a highly significant cause of morbidity and mort
Congenital heart defects are the most common birth defects in humans, and those that affect the proper alignment of the outflow tracts and septation of the ventricles are a highly significant cause of morbidity and mort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09d63dcba16c53213645ab4778e6904
https://europepmc.org/articles/PMC4813332/
https://europepmc.org/articles/PMC4813332/
Autor:
Jenny Xiang, Jason M. Butler, Olivier Elemento, Fuqiang Geng, Shahin Rafii, Susan Mathew, Sina Y. Rabbany, Daniel J. Nolan, Daylon James, Zev Rosenwaks, Stephen T. Chasen, Venkat R. Pulijaal, Michael Ginsberg, Bi-Sen Ding, Koji Shido, William Schachterle
Publikováno v:
Cell. 151(3):559-575
Summary ETS transcription factors ETV2 , FLI1 , and ERG1 specify pluripotent stem cells into induced vascular endothelial cells (iVECs). However, iVECs are unstable and drift toward nonvascular cells. We show that human midgestation c-Kit − lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb35809b6f8a7717a14b5ef80b90fd5
Publikováno v:
Developmental Biology. 361:439-449
The developing heart contains an inner tube of specialized endothelium known as endocardium, which performs multiple essential functions. In spite of the essential role of the endocardium in heart development and function, the transcriptional pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f471be59782dd06d972f04d5af955927
https://doi.org/10.1016/j.ydbio.2011.10.023
https://doi.org/10.1016/j.ydbio.2011.10.023
Autor:
William Schachterle, Shahin Rafii, Raphael Lis, José Gabriel Barcia Durán, Michael G. Poulos, Koji Shido, Arash Rafii Tabrizi, Jason M. Butler, Charles C. Karrasch, Nancy A. Speck, Joseph M. Scandura, Michael Ginsberg
Publikováno v:
Experimental Hematology. 44:S48-S49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::532c8b7aa81463c16a72cee3f39f7fd6
https://doi.org/10.1016/j.exphem.2016.06.065
https://doi.org/10.1016/j.exphem.2016.06.065